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Outcomes of Cataract Surgery in Individuals Receiving Intravitreal Anti-vascular Endothelial Growth Factor Agents: A Matched Retrospective Population-based Analysis

Project ID: 2022-939 / TRIM 2023 0970 041 001

Principle Investigators: Yaping Jin/Marko Popovic

Description: The literature conflicts on whether the risk of cataract surgery complications is higher in patients who received anti-vascular endothelial growth factor (VEGF) therapy, likely due to selection bias or small sample sizes in previous clinic-based studies. Prior studies investigated only a limited number of surgical complications and provide an incomplete picture. Surgeons need high-quality evidence to better plan cataract surgery in retinal patients who received anti-VEGF treatment. The objective of this project is to determine whether the incidence of cataract surgery complications in patients with retinal disease who received intravitreal anti- VEGF treatment is higher than those with retinal disease who did not receive anti- VEGF treatment.

PIA Approved: October 5, 2022