Healthcare Resource Utilization and Health Outcomes in Inflammatory Bowel Disease Patients of Biological Therapies: A Retrospective Cohort Study using Ontario Administrative Medical Records

Client: imshealth | brogan

Project ID: P2016-001 / 2018 0970 090 000

Research Question/Objectives: Ulcerative colitis and Crohn’s disease are the most prevalent types of inflammatory bowel diseases (IBD), with etiologies rooted in a complex interplay of genetic, microbial, and environmental factors. The overall objective of this retrospective study is to estimate the healthcare resource utilization and direct medical costs associated with Crohn’s disease and ulcerative colitis patients, when treated with biologic therapies, and compare the difference by type of index biologic used. Specifically, the research objectives of interest are:

• Determine the healthcare resource utilization and direct medical cost of IBD study patient cohort treated with a biologic and retained on it for at least 24 months, compared to a non-IBD cohort.
• Determine the occurrence of disease specific health outcomes for an IBD study patient cohort treated with a biologic and retained on it for at least 24 months, compared to a non-IBD cohort.
• Estimate and describe the proportion of patients that are primary non-responders and primary responders.

Results:

• Data set creation plan — pending
• Final deliverable