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Burden of illness of transfusion-dependent beta thalassemia and sickle cell disease in Canada

Client: IQVIA Solutions Canada Inc.

Project ID: P2022-122 / 2023 0970 328 000

Research Question/Objectives: The client seeks to conduct a feasibility study.

Phase One

Identify sample sizes:

  • of SCD and B-thalassemia cohorts.
  • of SCD patients with recurrent VOCs sub-group, and B-thalassemia patients with transfusion-dependent thalassemia (TDT) subgroups.

Phase Two


  • baseline characteristics of cohorts and sub-groups
  • acute and chronic complications of cohorts and sub-groups.
  • treatment patterns of cohorts and sub-groups.


In progress