Dr. Ko is a senior scientist at ICES, an interventional cardiologist at the Schulich Heart Centre of Sunnybrook Health Sciences Centre, and a professor of medicine at the University of Toronto. Despite the dramatic advances in cardiovascular medicine in the last several decades, there remains uncertainty about the application of these advances, particularly in many subgroups of patients that are not generally enrolled in clinical trials. Dr. Ko's research has focused on determining optimal clinical strategies and identifying opportunities for improvement in the prevention, treatment and outcome of cardiovascular disease. These research efforts are intended to provide critical information to improve the quality of healthcare, monitor changes over time, and guide decisions about the allocation of scarce healthcare resources.