Nick Daneman

Senior Adjunct Scientist (Full Status) ICES Central Populations & Public Health Research Program

Biography

Dr. Nick Daneman is a clinician scientist in the Division of Infectious Diseases, in the Department of Medicine, at Sunnybrook Health Sciences Centre, at the University of Toronto, and an adjunct scientist at ICES. He is supported through a CIHR Clinician Scientist Salary Award, and his research program is focused on optimizing the prevention and treatment of healthcare associated infection, with particular interest in Clostridium difficile infections, infections of critical care, surgical site infections, and antibiotic stewardship.

MSc, Clinical Epidemiology, University of Toronto
FRCPC, Infectious Diseases, University of Toronto
FRCPC, Internal Medicine, University of Toronto
MD, University of Toronto
BASc, McMaster University

Infectious diseases
Health services research

Division Head, Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre
Clinician Scientist, Infectious Diseases, University of Toronto
Associate Professor, Faculty of Medicine, University of Toronto

ICES Grants

Grant

2021 - 2022

Teasing apart the differential impact of variants of concern on COVID-19 severity and health inequities: a population-based genomic epidemiological investigation in Ontario and British Columbia

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Hogan C, Irvine MA, Janjua NZ, Kwong JC, Mishra S, Sander BH, Sbihi H
Co-Investigators: Abdia Y, Baral SD, Brown KA, Buchan S, Daneman N, Galanis E, Gubbay JB, Hoang L, Jassem AN, Krajden M, Kustra R, Mubareka S, Murti M, Patel S, Prystajecky NA, Rose CL, Sekirov I, Smolina E, Tyson JR, Vanniyasingam T, Velásquez García HA
Grant Type: Operating Grant
Grant Amount: $451,188

Grant

2021 - 2022

Incidence and risk factors of inappropriate antibiotic prescribing and related adverse health outcomes among Ontario long-term care residents and marginalized older community-dwelling adults with COVID-19 (I-CARE)

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Daneman N, MacFadden DR, Maxwell CJ, Mishra S, Schwartz KL
Co-Investigators: Brooks JI, Bowdish DM, Bronskill SE, Burrows LL, Langford BJ, Leung E, Leung V, Manuel DG, McGeer AJ, Morris AM, Nott C, Raybardhan S, So M, Soucy J
Grant Type: Operating Grant
Grant Amount: $308,904

Grant

2018 - 2021

Comprehensive Ontario Microbiology laBoratory Administrative daTa for AntiMicrobial Resistance (COMBAT-AMR)

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Brown KA, Daneman N
Co-Investigators: Sander B, Schwartz KL, Stukel T
Grant Type: Project Scheme Grant
Grant Amount: $608,176

Grant

2018 - 2021

Burden, cost, and development of asthma related to severe RSV infections

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Buchan S
Co-Investigators: Daneman N, Guttmann A, Kwong J, To T
Grant Type: SickKids-CIHR-IHDCYH New Investigator Grant
Grant Amount: $285,122

Grant

2015 - 2018

Reducing the burden of hospital-associated clostridium difficile infections in Canada through optimal prevention policies: a multidisciplinary individual-based modeling approach

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Brisson M, Sander B
Co-Investigators: Bergeron M, Daneman N, Dendukuri N, Drolet M, Frenette C, Garber G, Garenc C, Gilca R, Longtin Y, Loo V, McGeer A, Nanwa N, Pepin J, Valiquette L
Grant Type: Operating Grant
Grant Amount: $475,367

Grant

2014 - 2016

FRAMING-LTC: frailty and recognizing appropriate medications in geriatrics and long-term care

Granting Agency: Technology Evaluation in the Elderly Network (TVN) - National Centre of Excellence
Principal Investigators: Bell C, Bronskill S, Jeffs L, Maxwell C, Morris A
Co-Investigators: Daneman N
Grant Type: Catalyst Grant
Grant Amount: $265,990

Grant

2013 - 2014

Ethnic disparities in healthcare use for infectious diseases

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Kwong J
Co-Investigators: Chiu M, Daneman N, Rosella L, Smylie J
Grant Type: Operating Grant
Grant Amount: $63,897

See All

Awards & Recognition

01/06/2013

Sunnybrook Health Sciences Centre Department of Medicine Junior Investigator Award

2013: Awarded to Dr. Nick Daneman

See All

Journal Articles

Journal Article

27/03/2024

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

Ong SWX, Luo J, Fridman DJ, Lee SM, Johnstone J, Schwartz KL, Diong C, Patel SN, MacFadden D, Langford B, Tong SYC, Brown KA, Daneman N. Clin Microbiol Infect. 2024; Mar 27 [Epub ahead of print].

Journal Article

17/11/2023

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Driedger M, Daneman N, Brown K, Gold WL, Jorgensen SCJ, Maxwell C, Schwartz KL, Morris AM, Thiruchelvam D, Langford B, Leung E, MacFadden D. Microbiol Spectr. 2023; Nov 17 [Epub ahead of print].

Journal Article

01/08/2023

Antibiotic selection and duration for catheter-associated urinary tract infection in non-hospitalized older adults: a population-based cohort study

Langford BJ, Daneman N, Diong C, Lee SM, Fridman DJ, Johnstone J, MacFadden D, Mponponsuo K, Patel SN, Schwartz KL, Brown KA. Antimicrob Steward Healthc Epidemiol. 2023; 3(1):e132. Epub 2023 Aug 1.

Journal Article

19/06/2023

Estimating the incidence of first RSV hospitalization in children born in Ontario, Canada

Buchan SA, Chung H, To T, Daneman N, Guttmann A, Kwong JC, Murti M, Aryal G, Campigotto A, Chakraborty P, Gubbay J, Karnauchow T, Katz K, McGeer AJ, McNally JD, Mubareka S, Richardson D, Richardson SE, Smieja M, Zahariadis G, Deeks SL. J Pediatric Infect Dis Soc. 2023; Jun 19 [Epub ahead of print].

Journal Article

12/04/2023

Evaluating the impact of a virtual outpatient care program in preventing hospitalizations, emergency department visits and mortality for patients with COVID-19: a matched cohort study

Belzile MN, Lam P, Chan AK, Andany N, Simor A, Estrada-Codecido J, Ga’al A, Kapsack A, Mahmud A, Fridman D, Lee SM, Santoro A, Vandenbergh N, Daneman N. Clin Microbiol Infect. 2023; Apr 12 [Epub ahead of print].

Journal Article

31/03/2023

COVID-19 vaccination is associated with reduced outpatient antibiotic prescribing in older adults with confirmed SARS-CoV-2: a population wide cohort study

MacFadden DR, Maxwell C, Bowdish D, Bronskill S, Brooks J, Brown K, Burrows LL, Clarke A, Langford B, Leung E, Leung V, Manuel D, McGeer A, Nott C, Mishra S, Morris AM, Raybardhan S, Sapin M, Schwartz KL, So M, Soucy JPR, Daneman N. Clin Infect Dis. 2023; 77(3):362-70. Epub 2023 Mar 31.

Journal Article

13/02/2023

Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19

Schwartz KL, Wang J, Tadrous M, Langford BJ, Daneman N, Leung V, Gomes T, Friedman L, Daley P, Brown KA. CMAJ. 2023; 195(6):E220-6. Epub 2023 Feb 13.

Journal Article

26/12/2022

Antimicrobial resistance and mortality following E. coli bacteremia

Daneman N, Fridman D, Johnstone J, Langford BJ, Lee SM, MacFadden DM, Mponponsuo K, Patel SN, Schwartz KL, Brown KA. EClinicalMedicine. 2022; 56:101781. Epub 2022 Dec 26.

Journal Article

06/12/2022

Antibiotic susceptibility of urine culture specimens in Ontario: a population-based cohort study

Marchand-Austin A, Lee SM, Langford BJ, Daneman N, MacFadden DR, Diong C, Schwartz KL, Allen VG, Johnstone J, Patel SN, Garber GE, Brown KA. CMAJ Open. 2022; 10(4):E1044-51.

Journal Article

17/10/2022

Post-acute healthcare burden after SARS-CoV-2 infection: a retrospective cohort study

McNaughton CD, Austin PC, Sivaswamy A, Fang J, Abdel-Qadir H, Daneman N, Udell JA, Wodchis WP, Mostarac I, Lee DS, Atzema CL. CMAJ. 2022; 194:E1368-76. Epub 2022 Oct 17.

See All

News Coverage

News Release

29/06/2015

Get in touch with
Nick Daneman

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Nick Daneman

Biography

Education

Research Focus

Other Affiliations

ICES Grants

Teasing apart the differential impact of variants of concern on COVID-19 severity and health inequities: a population-based genomic epidemiological investigation in Ontario and British Columbia

Incidence and risk factors of inappropriate antibiotic prescribing and related adverse health outcomes among Ontario long-term care residents and marginalized older community-dwelling adults with COVID-19 (I-CARE)

Comprehensive Ontario Microbiology laBoratory Administrative daTa for AntiMicrobial Resistance (COMBAT-AMR)

Burden, cost, and development of asthma related to severe RSV infections

Reducing the burden of hospital-associated clostridium difficile infections in Canada through optimal prevention policies: a multidisciplinary individual-based modeling approach

FRAMING-LTC: frailty and recognizing appropriate medications in geriatrics and long-term care

Ethnic disparities in healthcare use for infectious diseases

Awards & Recognition

Sunnybrook Health Sciences Centre Department of Medicine Junior Investigator Award

Journal Articles

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Antibiotic selection and duration for catheter-associated urinary tract infection in non-hospitalized older adults: a population-based cohort study

Estimating the incidence of first RSV hospitalization in children born in Ontario, Canada

Evaluating the impact of a virtual outpatient care program in preventing hospitalizations, emergency department visits and mortality for patients with COVID-19: a matched cohort study

COVID-19 vaccination is associated with reduced outpatient antibiotic prescribing in older adults with confirmed SARS-CoV-2: a population wide cohort study

Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19

Antimicrobial resistance and mortality following E. coli bacteremia

Antibiotic susceptibility of urine culture specimens in Ontario: a population-based cohort study

Post-acute healthcare burden after SARS-CoV-2 infection: a retrospective cohort study

News Coverage

Residents of nursing homes with high antibiotic use are at higher risk of antibiotic-related adverse events

Length of antibiotic treatment depends more on the prescriber than the patient: ICES study

Nearly 27% reduction of C. difficile after public reporting introduced: study

Get in touch with
Nick Daneman

Nick Daneman

Biography

Education

Research Focus

Other Affiliations

ICES Grants

Teasing apart the differential impact of variants of concern on COVID-19 severity and health inequities: a population-based genomic epidemiological investigation in Ontario and British Columbia

Incidence and risk factors of inappropriate antibiotic prescribing and related adverse health outcomes among Ontario long-term care residents and marginalized older community-dwelling adults with COVID-19 (I-CARE)

Comprehensive Ontario Microbiology laBoratory Administrative daTa for AntiMicrobial Resistance (COMBAT-AMR)

Burden, cost, and development of asthma related to severe RSV infections

Reducing the burden of hospital-associated clostridium difficile infections in Canada through optimal prevention policies: a multidisciplinary individual-based modeling approach

FRAMING-LTC: frailty and recognizing appropriate medications in geriatrics and long-term care

Ethnic disparities in healthcare use for infectious diseases

Awards & Recognition

Sunnybrook Health Sciences Centre Department of Medicine Junior Investigator Award

Journal Articles

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Antibiotic selection and duration for catheter-associated urinary tract infection in non-hospitalized older adults: a population-based cohort study

Estimating the incidence of first RSV hospitalization in children born in Ontario, Canada

Evaluating the impact of a virtual outpatient care program in preventing hospitalizations, emergency department visits and mortality for patients with COVID-19: a matched cohort study

COVID-19 vaccination is associated with reduced outpatient antibiotic prescribing in older adults with confirmed SARS-CoV-2: a population wide cohort study

Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19

Antimicrobial resistance and mortality following E. coli bacteremia

Antibiotic susceptibility of urine culture specimens in Ontario: a population-based cohort study

Post-acute healthcare burden after SARS-CoV-2 infection: a retrospective cohort study

News Coverage

Residents of nursing homes with high antibiotic use are at higher risk of antibiotic-related adverse events

Length of antibiotic treatment depends more on the prescriber than the patient: ICES study

Nearly 27% reduction of C. difficile after public reporting introduced: study

Get in touch with Nick Daneman

Get in touch with
Nick Daneman