Pregnancy complications and new-onset maternal autoimmune disease
Scime NV, Grandi SM, Ray JG, Dennis CL, De Vera MA, Banack HR, Vigod SN, Boblitz A, Brown HK. Int J Epidemiol. 2024; 53(5):dyae115.
Objectives — To examine whether son-biased male to female (M:F) ratios at birth among linguistically different subgroups of Indian immigrants vary according to duration of residence in Canada.
Methods — We analyzed a retrospective cohort of 46 834 live births to Indian-born mothers who gave birth in Canada between 1993 and 2014. The M:F ratio at birth was calculated according to the sex of previous live births and stratified by (1) time since immigration to Canada (<10 and ≥10 years) and (2) mother tongue (Punjabi, Gujarati, Hindi, and other). We estimated adjusted odds ratios (aORs) using multivariate logistic regression to assess the probability of having a male newborn with 5-year increases in duration of residence in Canada for each language group. ORs were adjusted for married status, knowledge of English/French, maternal education at arrival and age and neighborhood income at delivery.
Results — Among all Indian immigrant women with two previous daughters, M:F ratios were higher than expected (1.92, 95% CI 1.73 to 2.12), particularly among those whose mother tongue was Punjabi (n = 25 287) (2.40, 95% CI 2.11 to 2.72) and Hindi (n = 7752) (1.63, 95% CI 1.05 to 2.52). M:F ratios did not diminish with longer duration in Canada (Punjabi 5-year aOR 1.03, 95% CI 0.81 to 1.31; Hindi 5-year aOR 0.94, 95% CI 0.42 to 2.17).
Conclusion — Among the Punjabi and Hindi women with two previous daughters, longer duration of residence did not attenuate son-biased M:F ratios at the third birth. Gender equity promotion may focus on Punjabi- and Hindi-speaking Indian immigrant women regardless of how long they have lived in Canada.
Brar A, Wanigaratne S, Pulver A, Ray JG, Urquia ML. J Obstet Gynaecol Can. 2017; 39(6):459-64.e.2. Epub 2017 Apr 23.
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