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Risk of nontuberculous mycobacterial pulmonary disease with obstructive lung disease


Nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasingly prevalent and especially common in the elderly. It is usually chronic, requiring complex therapy with suboptimal outcomes. Risk factors for NTM-PD may be covert, presumably disordered mucociliary defences, or overt structural lung abnormalities. In one study, 56% of NTM-PD patients had unexplained nontuberculous mycobacteria (NTM) and among the rest with structural lung disease, chronic obstructive pulmonary disease (COPD) was the most common predisposing condition.



Marras TK, Campitelli MA, Kwong JC, Lu H, Brode SK, Marchand-Austin A, Gershon AS, Jamieson FB. Eur Respir J. 2016; 48(3):928-31. Epub 2016 Jun 10.

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