Low-dose methotrexate and serious adverse events among older adults with chronic kidney disease
Muanda FT, Blake PG, Weir MA, Ahmadi F, McArthur E, Sontrop JM, Urquhart BL, Kim RB, Garg AX. JAMA Netw Open. 2023; 6(11):e2345132. Epub 2023 Nov 27.
Despite the temporal trend toward decreasing length of hospital stay for all medical conditions in North America, the effect of different lengths of hospitalization on short-term outcomes such as readmission or mortality has not been well studied. However, there is growing concern that very short stays in hospital may result in premature discharges, which may lead to worse outcomes for patients. This population-based study of elderly patients with obstructive airway disease in Ontario, Canada tests the hypothesis that very short initial hospital stays increase the short-term risk for readmission and mortality. Using a cohort of 32,384 elderly patients 65 years of age or older, 15-day rates of readmission and mortality were compared among patients with different lengths of stay. Although patients with hospital stays of less than 4 days were younger and had fewer comorbidities, they were 39% more likely to be readmitted and 45% more likely to die within 15 days of postdischarge compared with those who stayed 4 to 6 days. The risk was highest among patients whose stay was less than or equal to 1 hospital day; they had a 69% excess risk of readmission and a 2.08-fold increase in mortality compared with those who stayed in hospital for 2 days. This suggests that some elderly patients with obstructive airway disease may be prematurely discharged.
The ICES website uses cookies. If that’s okay with you, keep on browsing, or learn more about our Privacy Policy.