Derek MacFadden

Adjunct Scientist (Full Status) ICES uOttawa Populations & Public Health Research Program

PhD, Epidemiology, Harvard Chan School of Public Health
FRCPC, Infectious Diseases, University of Toronto
FRCPC, Internal Medicine, University of Toronto
MD, University of Toronto

Infectious diseases
Health services research

Clinician Scientist, The Ottawa Hospital Research Institute

ICES Grants

Grant

2024 - 2027

A province-wide assessment of outcomes in patients with lower extremity osteomyelitis to quantify burden and estimate feasibility for a randomized trial of oral beta-lactam versus non-beta-lactam antibiotics (OSTEO)

Granting Agency: University of Ottawa, Department of Medicine
Principal Investigators: MacFadden D
Co-Investigators: Nott C
Grant Type: Feasibility Grant
Grant Amount: $60,000

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Journal Articles

Journal Article

20/01/2026

Completeness of initial laboratory evaluation impacts chronic Hepatitis B outcomes

Imsirovic H, Hung J-H, Dumicho AY, Manuel D, MacFadden DR, Cooper CL. Livers. 2026; 6(1): 5.

Journal Article

13/05/2025

The burden of antimicrobial resistant bacteremia in Ontario: a population-wide analysis of attributable mortality from 110 pathogen-antibiotic combinations

Brown KA, Fridman DJ, Garber GE, Johnstone J, Langford BJ, Leung V, MacFadden D, Patel SN, Schwartz KL, Sander B, Daneman N. Clin Infect Dis. 2025; ciaf213 Epub 2025 May 13.

Journal Article

28/02/2025

Patterns of outpatient antibiotic prescribing in older adults by social determinants of healthcare access: a population-based retrospective cohort study

Sapin ME, Maxwell CJ, Clarke AE, Cooper C, So M, Schwartz KL, Daneman N, Mishra S, MacFadden D. Clin Microbiol Infect. 2025; S1198-743X(25)00086-2.

Journal Article

03/12/2024

Prevalence and predictors of concomitant bacterial infections in patients with respiratory viruses in Ontario: a cohort study

Wang Y, Swayze S, Brown KA, MacFadden DR, Lee SM, Schwartz KL, Daneman N, Langford BJ. Open Forum Infect Dis. 2024; 11(12):ofae701.

Journal Article

02/12/2024

Long-term risk of infection among patients colonized with antimicrobial-resistant pathogens: a population-wide cohort study

Blagojevic C, Brown KA, Diong C, Fridman DJ, Johnstone J, Langford BJ, Lee SM, MacFadden DR, Schwartz KL, Daneman N. Open Forum Infect Dis. 2024 Dec 2; 11(12):ofae712.

Journal Article

03/07/2024

Epidemiology and clinical relevance of persistent bacteraemia in patients with Gram-negative bloodstream infection: a retrospective cohort study

Ong SWX, Luo J, Fridman DJ, Lee SM, Johnstone J, Schwartz KL, Diong C, Patel SN, Macfadden DR, Langford BJ, Tong SYC, Brown KA, Daneman N. J Antimicrob Chemother. 2024; Jul 3 [Epub ahead of print].

Journal Article

17/05/2024

Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

Ong SWX, Luo J, Fridman DJ, Lee SM, Johnstone J, Schwartz KL, Diong C, Patel SN, MacFadden DR, Langford BJ, Tong SYC, Brown KA, Daneman N. Clin Infect Dis. 2024; May 17 [Epub ahead of print].

Journal Article

03/05/2024

The effect of COVID-19 vaccination on outpatient antibiotic prescribing in older adults: a self-controlled risk-interval study

Jorgensen SCJ, Brown K, Clarke AE, Schwartz KL, Maxwell C, Daneman N, Kwong JC, MacFadden DR. Clin Infect Dis. 2024; May 3 [Epub ahead of print].

Journal Article

27/03/2024

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

Ong SWX, Luo J, Fridman DJ, Lee SM, Johnstone J, Schwartz KL, Diong C, Patel SN, MacFadden D, Langford B, Tong SYC, Brown KA, Daneman N. Clin Microbiol Infect. 2024; Mar 27 [Epub ahead of print].

Journal Article

17/11/2023

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Driedger M, Daneman N, Brown K, Gold WL, Jorgensen SCJ, Maxwell C, Schwartz KL, Morris AM, Thiruchelvam D, Langford B, Leung E, MacFadden D. Microbiol Spectr. 2023; Nov 17 [Epub ahead of print].

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Contact Details

Get in touch with
Derek MacFadden

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Derek MacFadden

Education

Research Focus

Other Affiliations

ICES Grants

A province-wide assessment of outcomes in patients with lower extremity osteomyelitis to quantify burden and estimate feasibility for a randomized trial of oral beta-lactam versus non-beta-lactam antibiotics (OSTEO)

Journal Articles

Completeness of initial laboratory evaluation impacts chronic Hepatitis B outcomes

The burden of antimicrobial resistant bacteremia in Ontario: a population-wide analysis of attributable mortality from 110 pathogen-antibiotic combinations

Patterns of outpatient antibiotic prescribing in older adults by social determinants of healthcare access: a population-based retrospective cohort study

Prevalence and predictors of concomitant bacterial infections in patients with respiratory viruses in Ontario: a cohort study

Long-term risk of infection among patients colonized with antimicrobial-resistant pathogens: a population-wide cohort study

Epidemiology and clinical relevance of persistent bacteraemia in patients with Gram-negative bloodstream infection: a retrospective cohort study

Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The effect of COVID-19 vaccination on outpatient antibiotic prescribing in older adults: a self-controlled risk-interval study

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Get in touch with
Derek MacFadden

Derek MacFadden

Education

Research Focus

Other Affiliations

ICES Grants

A province-wide assessment of outcomes in patients with lower extremity osteomyelitis to quantify burden and estimate feasibility for a randomized trial of oral beta-lactam versus non-beta-lactam antibiotics (OSTEO)

Journal Articles

Completeness of initial laboratory evaluation impacts chronic Hepatitis B outcomes

The burden of antimicrobial resistant bacteremia in Ontario: a population-wide analysis of attributable mortality from 110 pathogen-antibiotic combinations

Patterns of outpatient antibiotic prescribing in older adults by social determinants of healthcare access: a population-based retrospective cohort study

Prevalence and predictors of concomitant bacterial infections in patients with respiratory viruses in Ontario: a cohort study

Long-term risk of infection among patients colonized with antimicrobial-resistant pathogens: a population-wide cohort study

Epidemiology and clinical relevance of persistent bacteraemia in patients with Gram-negative bloodstream infection: a retrospective cohort study

Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The effect of COVID-19 vaccination on outpatient antibiotic prescribing in older adults: a self-controlled risk-interval study

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Get in touch with Derek MacFadden

Get in touch with
Derek MacFadden