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Population-based stroke and dementia incidence trends: age and sex variations

Cerasuolo JO, Cipriano LE, Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Hachinski V. Alzheimers Dement. 2017; 13(10):1081-8. Epub 2017 Mar 28.


Background — We discovered a concomitant decline in stroke and dementia incidence rates at a whole population level in Ontario, Canada. This study explores these trends within demographic subgroups.

Methods — We analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013.

Results — For more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, and remained unchanged in those aged 65 to 79 years and decreased by 15.4% in those aged 80+ years.

Discussion — The concomitant decline in stroke and dementia incidence rates may depict how successful stroke prevention has targeted shared risk factors of both conditions, especially at advanced ages where such risk factors are highly prevalent. We lend support for the development of an integrated system of stroke and dementia prevention.

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Keywords: Dementia/Alzheimer disease Stroke

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