Paul Nathan

Senior Adjunct Scientist (Full Status) ICES Central Cancer Research Program

Biography

Dr. Paul Nathan is a pediatric hematologist/oncologist and Clinician Investigator at the Hospital for Sick Children in Toronto where he directs the Cancer Survivor Program. His research program focuses on long-term outcomes in survivors of childhood, adolescent and young adult cancer. This includes a studies investigating specific long-term toxicities of cancer therapy such as heart disease, second cancers and mental health disorders, as well on the utilization of healthcare resources by adults survivors of childhood and adolescent/young adult cancers. He is a member of the steering committees of several North American research groups focused on cancer outcomes. His research is funded by CIHR, the Canadian Cancer Society, OICR and the Pediatric Oncology Group of Ontario.

MSc, Clinical Health Sciences, McMaster University
MD, University of Toronto

Pediatric health
Outcomes research

Staff Oncologist, The Hospital for Sick Children
Director, Aftercare Program, Hospital for Sick Children
Senior Associate Scientist, SickKids Research Institute
Head, Solid Tumour Section, The Hospital for Sick Children
Professor, Department of Pediatrics and Institute of Health Policy, Management and Evaluation, University of Toronto
Member, Institute of Medical Science, University of Toronto

ICES Grants

Grant

2021 - 2026

Improving outcomes across the cancer journey for adolescents and young adult with central nervous system tumours: the IMPACT-CNS cohort

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Bartels U, Das S, Gupta S
Co-Investigators: Baxter NN, Hawkins CE, Hodgson DC, Lim-Fat MJ, Nathan PC, Pole JD, Purzner T, Sutradhar R, Tsang D
Grant Type: Project Grant
Grant Amount: $948,600

Grant

2021 - 2024

Physical, psychological, and functional late effects and healthcare use in survivors of adolescent and young adult cancer: a population-based study

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Gupta S
Co-Investigators: Baxter NN, Nathan PC, Pole JD, Srikanthan A, Sutradhar R, Yuan Y
Grant Type: Project Grant
Grant Amount: $484,245

Grant

2019 - 2020

The risk of late effects among childhood cancer survivors with Down Syndrome: a population-based study using health services data

Granting Agency: Sick Kids Garron Family Cancer Centre
Principal Investigators: Gupta S
Co-Investigators: Nathan P, Pole J, Sutradhar R
Grant Type: Pitblado Clinical Grant
Grant Amount: $59,804

Grant

2018 - 2025

Optimizing outcomes in survivors of childhood, adolescent and young adult cancer

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Nathan P
Co-Investigators: Baxter N, Grimshaw J, Gupta S, Ivers N, Pole J, Sutradhar R
Grant Type: Foundation Scheme Grant
Grant Amount: $2,729,448

Grant

2016 - 2019

Risk of mental health sequelae among childhood cancer survivors, mothers and siblings: a population-based study using health services data

Granting Agency: Canadian Cancer Society Research Institute
Principal Investigators: Gupta S
Co-Investigators: Kurdyak P, Nathan P, Pole J, Sutradhar R
Grant Type: Quality of Life Research Grant
Grant Amount: $241,017

Grant

2016 - 2018

The impact of the model of long-term follow-up care on adherence to surveillance for late effects among survivors of adolescents and young adult cancers

Granting Agency: Canadian Cancer Society Research Institute
Principal Investigators: Baxter N, Nathan P
Co-Investigators: Pole J, Sutradhar R
Grant Type: Quality of Life Research Grant
Grant Amount: $192,790

Grant

2015 - 2017

Predictors of admission to long-term care facilities in the population

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Manuel D
Co-Investigators: Tanuseputro P, Bronskill S, Gruneir A, Patrick J, Costa A, Welch V
Grant Type: Operating Grant
Grant Amount: $347,283

Grant

2015 - 2017

A population-based study of long-term outcomes in survivors of allogeneic hematopoietic stem cell transplantation during childhood, adolescence or young adulthood

Granting Agency: C17 (Children's Cancer and Blood Disorders) Research Network
Principal Investigators: Schechter T
Co-Investigators: Nathan P, Pole J
Grant Type: Research Grant
Grant Amount: $107,125

Grant

2015 - 2017

The effect of locus of care upon adolescent and young adult cancer outcomes: an IMPACT cohort study

Granting Agency: Alex's Lemonade Stand Foundation
Principal Investigators: Gupta S
Co-Investigators: Nathan P
Grant Type: Young Investigator Program
Grant Amount: $99,988

Grant

2014 - 2019

Initiative to maximize progress in adolescent and young adult (AYA) cancer therapy (IMPACT)

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Baxter N, Nathan P
Co-Investigators: Barr R, Grenberg M, Gupta A, Gupta S, Pole J, Rapoport A, Sawka A, Sussman J, Sutradhar R, Wasserman J
Grant Type: Operating Grant
Grant Amount: $913,872

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Awards & Recognition

01/06/2010

Early Researcher Award

2010-2013: $100,000 awarded to Dr. Paul Nathan by the Ministry of Research and Innovation.

Awards & Recognition

10/01/2010

American Society of Clinical Oncology (ASCO) Award

2010: Study by Dr. Paul Nathan on "Cancer screening in adult survivors of childhood cancer” selected as one of the “Major research advances in cancer treatment, prevention and screening” by ASCO.

Awards & Recognition

10/01/2010

American Society of Clinical Oncology (ASCO) Award

2008: Study by Dr. Paul Nathan on "Risk based care in survivors of childhood cancer" selected as one of the “Major research advances in cancer treatment, prevention and screening” by ASCO.

Awards & Recognition

10/01/2010

American Society of Clinical Oncology (ASCO) Merit Award

2003: Presented to Dr. Paul Nathan by ASCO.

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Journal Articles

Journal Article

11/03/2024

Longitudinal adherence to surveillance for late effects of cancer treatment: a population-based study of adult survivors of childhood cancer

Shuldiner J, Sutradhar R, Lau C, Shah N, Lam E, Ivers N, Nathan PC. CMAJ. 2024; 196(9):E282-294. Epub 2024 Mar 11.

Journal Article

20/10/2023

Specialty palliative care and symptom severity and control in adolescents and young adults with cancer

Gupta S, Li Q, Kassam A, Rapoport A, Widger K, Chalifour K, Baxter NN, Nathan PC, Coburn NG, Sutradhar R. JAMA Netw Open. 2023; 6(10):e2338699. Epub 2023 Oct 20.

Journal Article

03/08/2023

Rates and predictors of visits to primary care physicians during and after treatment of childhood acute lymphoblastic leukemia: a population-based cohort study

Breakey VR, Sutradhar R, Nathan PC, Patel S, Wheaton L, Li Q, Bassal M, Gibson P, Pole JD, Athale U, Gupta S. Pediatr Blood Cancer. 2023; Aug 3 [Epub ahead of print].

Journal Article

04/04/2023

Treatment patterns and outcomes in adolescents and young adults with nodular lymphocyte-predominant Hodgkin lymphoma: an IMPACT cohort study

Punnett A, Baxter NN, Hodgson D, Sutradhar R, Pole JD, Lau C, Nathan PC, Gupta S. Br J Haematol. 2023; Apr 4 [Epub ahead of print].

Journal Article

27/03/2023

Prevalence, severity, and predictors of symptom burden among adolescents and young adults with cancer

Gupta S, Li Q, Nathan PC, D’Agostino N, Baxter NN, Fox C, Chalifour K, Coburn N, Sutradhar R. Cancer Med. 2023; 12(10):11773-85. Epub 2023 Mar 7.

Journal Article

25/01/2023

The burden of surviving childhood medulloblastoma: a population-based, matched cohort study in Ontario, Canada

Coltin H, Pequeno P, Liu N, Tsang DS, Gupta S, Taylor MD, Bouffet E, Nathan PC, Ramaswamy V. J Clin Oncol. 2023; 41(13):2372-81. Epub 2023 Jan 25.

Journal Article

18/07/2022

Incidence of cardiovascular disease and mortality in childhood solid organ transplant recipients: a population-based study

Brar S, Dixon SN, Paterson JM, Dirk J, Hahn E, Kim SJ, Ng V, Solomon M, Vasilevska-Ristovska J, Banh T, Nathan PC, Parekh RS, Chanchlani R. Pediatr Nephrol. 2022; Jul 18 [Epub ahead of print].

Journal Article

28/02/2022

Risk of COVID-19 infections and of severe complications among survivors of childhood, adolescent, and young adult cancer: a population-based study in Ontario, Canada

Gupta S, Sutradhar R, Alexander S, Science M, Lau C, Nagamuthu C, Agha M, Nathan PC, Hodgson D. J Clin Oncol. 2022; 40(12):1281-90. Epub 2022 Feb 28.

Journal Article

19/01/2022

Obstetrical and perinatal outcomes in female survivors of childhood and adolescent cancer: a population-based cohort study

Zgardau A, Ray JG, Baxter NN, Nagamuthu C, Park AL, Gupta S, Nathan PC. J Natl Cancer Inst. 2022; 114(4):553-64. Epub 2022 Jan 19.

Journal Article

14/01/2022

Impact of locus of care on outcomes in adolescents and young adults with osteosarcoma and Ewing sarcoma treated at pediatric versus adult cancer centers: An IMPACT cohort study

Mortazavi M, Baxter NN, Gupta S, Gupta AA, Lau C, Nagamuthu C, Nathan PC. Pediatr Blood Cancer. 2022; 69(4):e29458. Epub 2022 Jan 14.

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News Coverage

News Release

22/02/2018

Childhood cancer survivors at higher risk of mental health events

News Release

25/09/2015

Adult survivors of childhood cancer benefit from specialized survivor clinic attendance: study

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Contact Details

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Paul Nathan

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Paul Nathan

Biography

Education

Research Focus

Other Affiliations

ICES Grants

Improving outcomes across the cancer journey for adolescents and young adult with central nervous system tumours: the IMPACT-CNS cohort

Physical, psychological, and functional late effects and healthcare use in survivors of adolescent and young adult cancer: a population-based study

The risk of late effects among childhood cancer survivors with Down Syndrome: a population-based study using health services data

Optimizing outcomes in survivors of childhood, adolescent and young adult cancer

Risk of mental health sequelae among childhood cancer survivors, mothers and siblings: a population-based study using health services data

The impact of the model of long-term follow-up care on adherence to surveillance for late effects among survivors of adolescents and young adult cancers

Predictors of admission to long-term care facilities in the population

A population-based study of long-term outcomes in survivors of allogeneic hematopoietic stem cell transplantation during childhood, adolescence or young adulthood

The effect of locus of care upon adolescent and young adult cancer outcomes: an IMPACT cohort study

Initiative to maximize progress in adolescent and young adult (AYA) cancer therapy (IMPACT)

Awards & Recognition

Early Researcher Award

American Society of Clinical Oncology (ASCO) Award

American Society of Clinical Oncology (ASCO) Award

American Society of Clinical Oncology (ASCO) Merit Award

Journal Articles

Longitudinal adherence to surveillance for late effects of cancer treatment: a population-based study of adult survivors of childhood cancer

Specialty palliative care and symptom severity and control in adolescents and young adults with cancer

Rates and predictors of visits to primary care physicians during and after treatment of childhood acute lymphoblastic leukemia: a population-based cohort study

Treatment patterns and outcomes in adolescents and young adults with nodular lymphocyte-predominant Hodgkin lymphoma: an IMPACT cohort study

Prevalence, severity, and predictors of symptom burden among adolescents and young adults with cancer

The burden of surviving childhood medulloblastoma: a population-based, matched cohort study in Ontario, Canada

Incidence of cardiovascular disease and mortality in childhood solid organ transplant recipients: a population-based study

Risk of COVID-19 infections and of severe complications among survivors of childhood, adolescent, and young adult cancer: a population-based study in Ontario, Canada

Obstetrical and perinatal outcomes in female survivors of childhood and adolescent cancer: a population-based cohort study

Impact of locus of care on outcomes in adolescents and young adults with osteosarcoma and Ewing sarcoma treated at pediatric versus adult cancer centers: An IMPACT cohort study

News Coverage

Childhood cancer survivors at higher risk of mental health events

Adult survivors of childhood cancer benefit from specialized survivor clinic attendance: study

Get in touch with
Paul Nathan

Paul Nathan

Biography

Education

Research Focus

Other Affiliations

ICES Grants

Improving outcomes across the cancer journey for adolescents and young adult with central nervous system tumours: the IMPACT-CNS cohort

Physical, psychological, and functional late effects and healthcare use in survivors of adolescent and young adult cancer: a population-based study

The risk of late effects among childhood cancer survivors with Down Syndrome: a population-based study using health services data

Optimizing outcomes in survivors of childhood, adolescent and young adult cancer

Risk of mental health sequelae among childhood cancer survivors, mothers and siblings: a population-based study using health services data

The impact of the model of long-term follow-up care on adherence to surveillance for late effects among survivors of adolescents and young adult cancers

Predictors of admission to long-term care facilities in the population

A population-based study of long-term outcomes in survivors of allogeneic hematopoietic stem cell transplantation during childhood, adolescence or young adulthood

The effect of locus of care upon adolescent and young adult cancer outcomes: an IMPACT cohort study

Initiative to maximize progress in adolescent and young adult (AYA) cancer therapy (IMPACT)

Awards & Recognition

Early Researcher Award

American Society of Clinical Oncology (ASCO) Award

American Society of Clinical Oncology (ASCO) Award

American Society of Clinical Oncology (ASCO) Merit Award

Journal Articles

Longitudinal adherence to surveillance for late effects of cancer treatment: a population-based study of adult survivors of childhood cancer

Specialty palliative care and symptom severity and control in adolescents and young adults with cancer

Rates and predictors of visits to primary care physicians during and after treatment of childhood acute lymphoblastic leukemia: a population-based cohort study

Treatment patterns and outcomes in adolescents and young adults with nodular lymphocyte-predominant Hodgkin lymphoma: an IMPACT cohort study

Prevalence, severity, and predictors of symptom burden among adolescents and young adults with cancer

The burden of surviving childhood medulloblastoma: a population-based, matched cohort study in Ontario, Canada

Incidence of cardiovascular disease and mortality in childhood solid organ transplant recipients: a population-based study

Risk of COVID-19 infections and of severe complications among survivors of childhood, adolescent, and young adult cancer: a population-based study in Ontario, Canada

Obstetrical and perinatal outcomes in female survivors of childhood and adolescent cancer: a population-based cohort study

Impact of locus of care on outcomes in adolescents and young adults with osteosarcoma and Ewing sarcoma treated at pediatric versus adult cancer centers: An IMPACT cohort study

News Coverage

Childhood cancer survivors at higher risk of mental health events

Adult survivors of childhood cancer benefit from specialized survivor clinic attendance: study

Get in touch with Paul Nathan

Get in touch with
Paul Nathan