Machine learning identifies clusters of multimorbidity among decedents with inflammatory bowel disease
Postill G, Harish V, Itanyi IU, Tang F, Buajitti E, Kuenzig ME, Rosella LC, Benchimol EI. Commun Med (Lond). 2025; 5(1):476.
Purpose — Unplanned rehospitalization at a hospital other than the initial hospital may contribute to poor outcomes. We examined the location of rehospitalizations and assessed outcomes following critical illness in a single-payer healthcare system.
Materials and Methods — Population-based retrospective cohort study using linked datasets (2012–2017) from Ontario, Canada including adults (≥18 years) with an unplanned rehospitalization within 30-days after an index hospitalization that included an ICU stay with mechanical ventilation. Outcomes were the percentage of 30-day rehospitalizations at non-index hospitals, mortality and costs. We employed logistic regression and generalized linear models to assess associations.
Results — There were 14,997 (16.4%) 30-day rehospitalizations. Of these 2765 (18.4%) occurred in a non-index hospital. Distance of home residence from the index hospital was the strongest predictor of a non-index rehospitalization (adjusted odds ratio (aOR) 8.40, 95%CI 7.05–10.01, highest vs. lowest distance quintile). Within 30-days of rehospitalization, deaths (aOR 0.91, 95%CI (0.80–1.04)) and total healthcare costs (adjusted relative risk 1.03 (1.00–1.06)), were similar for patients readmitted to the index or a non-index hospital.
Conclusion — Non-index rehospitalization within 30-days of initial discharge is common following critical illness. These rehospitalizations were not significantly associated with an increased risk of harm or higher costs in a single-payer healthcare system.
Hill AD, Scales DC, Fowler RA, Fu L, Hua M, Wunsch H. J Crit Care. 2022; Jun 29 [Epub ahead of print].
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