The performance of marginal structural models for estimating risk differences and relative risks using weighted univariate generalized linear models
Austin PC. Stat Methods Med Res. 2024; Apr 24 [Epub ahead of print].
Knowledge of the acute cardiovascular effects of cannabis consumption remains largely unknown, and is important given the changing landscape of legalization of recreational cannabis use. “4/20” is an annual event where many individuals gather to consume cannabis. An increased risk of adverse health events such as motor vehicle accidents have previously been reported to occur on “4/20”. In this study, population-based administrative databases in Ontario, Canada were used to evaluate the association between “4/20” and cardiovascular events. An increased risk of cardiovascular events on a population-level was not observed on “4/20”. Additional research into the changes in prevalence of use of cannabis with recreational legalization and acute and chronic risk with cannabis use is suggested.
Singh SM, Koh M, Fang J, Ko DT. Can J Cardiol. 2019; 35(11):1589-91. Epub 2019 May 22.
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