Low-dose methotrexate and serious adverse events among older adults with chronic kidney disease
Muanda FT, Blake PG, Weir MA, Ahmadi F, McArthur E, Sontrop JM, Urquhart BL, Kim RB, Garg AX. JAMA Netw Open. 2023; 6(11):e2345132. Epub 2023 Nov 27.
Objectives — To determine whether attending diabetes education is associated with blood glucose self-monitoring among unselected older adults in routine clinical care.
Method — A cross-sectional population-based study was carried out on 15,190 people with diabetes aged 65-79 years. Subjects were identified using a registry of doctor-diagnosed diabetes derived from administrative data, and attendance at diabetes education centres (DECs) was determined from a separate registry of DEC utilization for 2006. Outcomes were derived using administrative data. The primary outcome was prescriptions filled for glucose self-monitoring supplies. The secondary outcomes were prescriptions for antihypertensive drugs, prescriptions for lipid-lowering drugs and eye examinations.
Results — DEC attendance was associated with glucose self-monitoring, after adjusting for baseline differences between attendees and non-attendees (adjusted odds ratio 6.45, 95% confidence interval 5.61 to 7.42). All of the secondary outcomes were also independently associated with DEC attendance.
Conclusions — This study suggests that diabetes education is associated with self-management behaviour in real-world clinical care. These findings support the effectiveness of self-management education programmes to increase self-care behaviours.
Millar A, Cauch-Dudek K, Shah BR. J Eval Clin Pract. 2010; 16(4):790-3. Epub 2010 Jun 14.
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