Severity of chronic kidney disease and outcomes after admission to the intensive care unit
El Wadia H, Beauregard N, Silver SA, Wald R, Akbari A, Fremont D, Ramsay T, Knoll GA, Clark EG, Hundemer GL. JAMA Netw Open. 2026; 9(6): e2620192.
Objective — To examine from a Canadian population-based perspective the incidence and etiology of long-term hospital utilization among persons living with traumatic brain injury (TBI) by age and sex.
Design — Retrospective cohort study.
Setting — Acute care hospitals in Ontario.
Participants — Index cases of TBI (N=29,269) were identified from the Discharge Abstract Database for fiscal years 2002/03-2009/10 and were followed up to 36 months after injury.
Interventions — Not applicable.
Main Outcome Measures — Re-hospitalizations were defined as an admission to an acute care facility that occurred up to 36 months following index injury. Diagnoses associated with subsequent re-hospitalizations were examined by age and sex.
Results — 35.5% (n=10,390) of patients with TBI were subsequently hospitalized during the 3 year follow-up period. Multivariable logistic regression (controlling for index admission hospital) identified males, older age, mechanism of injury being a fall, greater injury severity, rural residence, greater comorbidity and psychiatric comorbidity to be significant predictors of re-hospitalization in a three year period post injury. The most common causes for re-hospitalization differed by age and sex.
Conclusions — Re-hospitalizations after TBI are common. Factors associated with re-hospitalizations can inform long term post discharge planning. Findings also support examining causes for re-hospitalization by age and sex.
Saverino C, Swaine B, Jaglal S, Lewko J, Vernich L, Voth J, Calzavara A, Colantonio A. Arch Phys Med Rehabil. 2016; 97(2 Suppl):S19-25. Epub 2015 May 2.
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