Intravenous thrombolysis for acute ischemic stroke across kidney function
Bota SE, Dixon S, Kapral MK, Hackam D, Sood MM, Sontrop JM, Garg AX. Nephrol Dial Transplant. 2026; Oct 1 [Epub ahead of print].
Warfarin is commonly prescribed to treat and prevent thrombosis in individuals with atrial fibrillation, central venous catheters, mechanical heart valves, deep vein thrombosis, and pulmonary embolism.1-8 Despite its widespread use, warfarin has a narrow therapeutic index. Many variables may influence its action and increase the risk of hemorrhagic complications, even with stable dosing. Concomitant use of medications, particularly short-term antibiotics,
may be an important source of such an interaction.