Pregnancy outcomes after living kidney donation
Wang C, Naylor KL, McArthur E, King JA, Sontrop JM, Beyene J, Connaughton D, Hendren E, Hladunewich M, Lam NN, Lentine KL, Lyons R, McDonald SD, Roshanov PS, Youngson E, Garg AX. JAMA. 2026; E1-10.
Background — Patients with diabetes receiving chronic in-centre hemodialysis face healthcare challenges. We examined the prevalence of gaps in their diabetes care, explored regional differences, and determined predictors of care gaps.
Methods — We conducted a population-based retrospective study between January 1 2016 and January 1 2018 in Ontario Canada. We included adults with prevalent diabetes mellitus receiving in-centre hemodialysis as of January 1 2018 and examined the proportion with 1) insufficient or excessive glycemic monitoring, 2) suboptimal screening for diabetes-related complications (retinopathy and cardiovascular screening), 3) hospital encounters for hypo- or hyperglycemia, and 4) hospital encounters for hypertension in the 2 years prior (January 1 2016-January 1 2018). We then identified patient, provider and health system factors associated with >1 care gap and used multivariable logistic regression to determine predictors. Further, we used Geographic Information Systems to explore spatial variation in gaps.
Results — There were 4,173 patients with diabetes receiving in-centre hemodialysis. Mean age was 67 years, 39% were women and the majority were of lower socioeconomic status. Approximately 42% of patients had >1 diabetes care gap, the most common being suboptimal retinopathy screening (53%). Significant predictors of more than one gap included younger age, female sex, shorter duration of diabetes, dementia, fewer specialist visits and not seeing a physician for diabetes. There was evidence of spatial variation in care gaps across our region.
Conclusions — There are opportunities to improve diabetes care in patients receiving in-centre hemodialysis, particularly screening for retinopathy. Focused efforts to bring diabetes support to high-risk individuals might improve their care and outcomes.
Clemens KK, Ouédraogo AM, Garg AX, Silver SA, Nash DM. Kidney360. 2021; 2(4):653-65. Epub 2021 Feb 25.
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