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Non-ABO red cell antibodies and risk of COVID-19


It is not known whether non-ABO antibodies confers any protective effect against SARS-CoV-2 infection or COVID-19 severe illness, alone, or in conjunction with O blood group. This cohort study included 413,576 persons in Ontario, Canada with known ABO blood group and non-ABO antibody screen status, and who subsequently underwent SARS-CoV-2 viral RNA PCR testing between January and November 2020. The risk of SARS-CoV-2 infection or COVID-19 severe illness was not associated with the presence of non-ABO antibodies, even among persons with O blood group.



Ray JG, Colacci M, Schull MJ, Vermeulen MJ, Park AL. Int J Infect Dis. 2021; 108:179-82. Epub 2021 May 19.

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