Association between infertility and incident onset of systemic autoimmune rheumatic disease after childbirth: a population-based cohort study
Scime NV, Velez MP, Choi MY, Ray JG, Boblitz A, Brown HK. Hum Reprod. 2024; deae253.
During pregnancy, women with asthma may be at higher risk of exacerbation. The objective of this study was to determine whether women with asthma in Ontario, Canada have increased health services utilization (HSU) during pregnancy.
Rates of asthma-specific, asthma-related and non-pregnancy-related HSU were calculated in a population-based cohort of pregnant women with asthma. Poisson regression with repeated measures was used to determine adjusted rate ratios and 95% confidence intervals of HSU during and one year after pregnancy, compared to the year before pregnancy.
The cohort consisted of 103,976 women. Compared to the year prior to pregnancy, hospitalization rates per 100 person-months during pregnancy increased 30% for asthma (0.016 to 0.020), 24% for asthma-related conditions (0.012 to 0.015) and decreased 37% for non-pregnancy-related conditions (0.24 to 0.15). Emergency department visits for asthma and asthma-related conditions did not significantly increase during pregnancy. During pregnancy, physician office visits decreased 19% for asthma (2.20 to 1.79), 10% for asthma-related conditions (9.44 to 8.47) and increased 77% for non-pregnancy-related conditions (5.64 to 9.82).
Hospitalizations for asthma and asthma-related conditions increased during pregnancy, demonstrating that the overall increase in non-pregnancy-related physician office visits may not meet the primary care needs of pregnant women with asthma.
To T, Feldman LY, Zhu J, Gershon AS. Eur Respir J. 2018; 51(4):1800209. Epub 2018 Mar 8.
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