Pregnancy outcomes after living kidney donation
Wang C, Naylor KL, McArthur E, King JA, Sontrop JM, Beyene J, Connaughton D, Hendren E, Hladunewich M, Lam NN, Lentine KL, Lyons R, McDonald SD, Roshanov PS, Youngson E, Garg AX. JAMA. 2026; E1-10.
Objectives — This study aimed to identify a threshold in annual surgeon volume associated with increased risk of revision (for any cause) and deep infection requiring surgery following primary elective total knee arthroplasty (TKA).
Design — A propensity score matched cohort study.
Setting — Ontario, Canada.
Participants — 169 713 persons who received a primary TKA between 2002 and 2016, with 3-year postoperative follow-up.
Main Outcome Measures — Revision arthroplasty (for any cause), and the occurrence of deep surgical infection requiring surgery.
Results — Based on restricted cubic spline analysis, the threshold for increased probability of revision and deep infection requiring surgery was <70 cases/year. After matching of 51 658 TKA recipients from surgeons performing <70 cases/year to TKA recipients from surgeons with greater than 70 cases/year, patients in the former group had a higher rate of revision (for any cause, 2.23% (95% Confidence Interval (CI) 1.39 to 3.07) vs 1.70% (95% CI 0.85 to 2.55); Hazard Ratio (HR) 1.33, 95% CI 1.21 to 1.47, p<0.0001) and deep infection requiring surgery (1.29% (95% CI 0.44 to 2.14) vs 1.09% (95% CI 0.24 to 1.94); HR 1.33, 95% CI 1.17 to 1.51, p<0.0001).
Conclusions — For primary TKA recipients, cases performed by surgeons who had performed fewer than 70 TKAs in the year prior to the index TKA were at 31% increased relative risk of revision (for any cause), and 18% increased relative risk for deep surgical infection requiring surgery, at 3-year follow-up.
Okoro T, Tomescu S, Paterson JM, Ravi B. BMJ Surg Interv Health Technologies. 2021; 3:e000072. Epub 2021 Apr 2.
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