Differences in admission to trauma centres by sex among adults with traumatic brain injury: a population-based cohort study
Angeloni N, Veroniki A-A, Angriman F, Scales DC, Adhikari N. CMAJ. 2026; 198(23): E885-93.
Clinical researchers frequently assess the statistical significance of the difference between two means by examining whether the two 95% confidence intervals overlap. The purpose of this brief communication is to illustrate that the 95% confidence intervals for two means can overlap and yet the two means can be statistically significantly different from one another at the alpha = 0.05 level.