A study of resource use and burden of illness due to COVID-19 among patients who are immunocompromised in Ontario, Canada (ARCTIC)

Client: Broadstreet Health Economics and Outcomes Research

Project ID: P2022-145/2024 0970 344 000

Research Question/Objectives: There is a need to understand the continued burden of COVID-19 in high-risk immunocompromised patients in Canada. Results will contribute to better understanding of the burden in the wider scientific community, and provide inputs to economic analyses considered by decision-makers in Canada.

Primary:
1) To describe the burden of illness (BOI), resource utilization (RU) and healthcare costs among patients who are immunocompromised and non-immunocompromised, hospitalized with COVID-19, by COVID-19 vaccination status and COVID-19 wave.

Secondary:
1) To compare BOI, RU and healthcare costs among immunocompromised vs non-immunocompromised patients hospitalized with COVID-19, by COVID-19 vaccination status and COVID-19 wave.

Exploratory, if feasible:
1) explore size of the population with immunocompromising conditions in Ontario overall and per condition;
2) explore documented attack rate of COVID-19 among immunocompromised patients by COVID-19 vaccination status and COVID-19 wave;
3) explore RU and BOI among patients hospitalized with COVID-19 by IC condition;
4) explore RU and BOI among patients hospitalized with COVID-19 living in long-term care (LTC)

Results: December 2024