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Risk of subsequent thromboembolism for patients with pre-eclampsia

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Inherited thrombophilias affect over 16% of people and predispose them to venous thromboembolism. Pre-eclampsia is associated with occlusion of the placental spiral arteries. Thrombophilias may cause thrombosis of placental vessels, thereby explaining the link between thrombophilia and pre-eclampsia. We tested the hypothesis that women with pre-eclampsia have a higher risk of subsequent venous thromboembolism.

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van Walraven C, Mamdani M, Cohn A, Katib Y, Walker M, Rodger MA. BMJ. 2003; 326(7393):791-2.

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Contributing ICES Scientists