We found that risk of SARS-CoV-2 breakthrough infection did not meaningfully differ between a population-based cohort of vaccinated people with HIV and a matched cohort of people without HIV after accounting for sociodemographic factors, previous SARS-CoV-2 infection, SARS-CoV-2 testing patterns and COVID-19 vaccine doses (14 December 2020 to 5 May 2024). However, rates of breakthrough infection were higher among men with HIV compared to without HIV during the pre-Omicron era.
Freitas C, Cooper CL, Kroch AE, Buchan SA, Moineddin R, Arbess G, Benoit AC, Chambers C, Habanyama M, Kendall CE, Kwong JC, Mbuagbaw L, McCullagh J, Moqueet N, Nambiar D, Tran V, Walmsley S, Burchell AN; CHESS Study Team; Langlois MA, Rueda S, Yeung A, Mah A, Lee S, Patrikar A, Taylor D. AIDS. 2026; 40(1): 119-122.
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