The impact of semaglutide on peri-operative cardiovascular outcomes in diabetes
Castrillon F, Carter B, McClure A, Welk B, Clemens KK. Diabetes Obes Metab. 2025 Sep 24 [Epub ahead of print].
Aims — To compare the prevalence of diabetes in pregnancy, pregnancy care and adverse pregnancy outcomes in on-reserve First Nations women vs. non-First Nations women in Ontario, Canada.
Methods — A retrospective population-based cohort study was performed. All 487,368 live singleton hospital deliveries between 1 April 2002 and 31 March 2010 were identified. Outcomes were defined by linking mothers and infants to provincial healthcare administrative databases.
Results — Diabetes in pregnancy was more prevalent in First Nations women (10.3 vs. 6.0%). They received less pregnancy care and had higher rates of adverse outcomes than non-First Nations women with diabetes.
Conclusions — First Nations women are at a higher risk of diabetes in pregnancy and adverse outcomes. This highlights the need for increased care for pregnant First Nations women.
Liu SL, Shah BR, Naqshbandi M, Tran V, Harris SB. Diabet Med. 2012; 29(8):e180-3. Epub 2012 Jul 15.
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