{"id":20584,"date":"2024-10-28T14:17:17","date_gmt":"2024-10-28T18:17:17","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=private_project&p=20584"},"modified":"2025-08-15T13:38:10","modified_gmt":"2025-08-15T17:38:10","slug":"burden-of-illness-of-transfusion-dependent-beta-thalassemia-disease-in-canada","status":"publish","type":"private_project","link":"https:\/\/www.ices.on.ca\/fr\/services-for-researchers\/all-projects\/private-sector-projects\/burden-of-illness-of-transfusion-dependent-beta-thalassemia-disease-in-canada\/","title":{"rendered":"Burden of illness of transfusion-dependent beta thalassemia disease in Canada"},"content":{"rendered":"

Client:<\/strong>\u00a0IQVIA Solutions Canada Inc.<\/p>\n

Project ID:\u00a0<\/strong>P2022-122B \/ 2024 0970 328 001<\/p>\n

Research Question\/Objectives:\u00a0<\/strong>Hemoglobinopathies represent a group of lifelong, autosomal recessive genetic disorders that affect the structure or production of hemoglobin (Hb) molecule. \u03b2-thalassemia is caused by a mutation that impacts \u03b2-globulin chains. Patients with \u03b2-thalassemia do not produce hemoglobin endogenously and therefore must receive red blood cell transfusions. Severe forms of thalassemia that require regular blood transfusions are known as transfusion-dependent thalassemia (TDT).<\/p>\n

Objectives:<\/strong><\/p>\n

    \n
  1. Describe baseline characteristics of cohorts<\/li>\n
  2. Describe acute and chronic complications of cohorts<\/li>\n
  3. Describe treatment patterns of cohorts<\/li>\n
  4. Describe the all-cause healthcare resource utilization (HCRU).<\/li>\n<\/ol>\n

    Status:\u00a0<\/strong>Completed<\/p>\n

    Results:<\/strong> February 2026<\/p>\n","protected":false},"excerpt":{"rendered":"

    Client:\u00a0IQVIA Solutions Canada Inc. Project ID:\u00a0P2022-122B \/ 2024 0970 328 001 Research Question\/Objectives:\u00a0Hemoglobinopathies represent a group of lifelong, autosomal recessive genetic disorders that affect the structure or production of hemoglobin (Hb) molecule. \u03b2-thalassemia is caused by a mutation that impacts \u03b2-globulin chains. Patients with \u03b2-thalassemia do not produce hemoglobin endogenously and therefore must receive red […]<\/p>\n","protected":false},"template":"","organization_type":[],"project_status":[105],"response_type":[],"class_list":["post-20584","private_project","type-private_project","status-publish","hentry","project_status-completed"],"acf":{"project_id":"P2022-122B \/ 2024 0970 328 001","project_id_year":2024,"ices_scientist":"","principal_investigators":null,"knowledge_user":"","client":"","objectives":"","results":"","availability_of_results":"","pia_approved":null,"infographic":"","sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":""},"yoast_head":"\nBurden of illness of transfusion-dependent beta thalassemia disease in Canada | ICES<\/title>\n<meta name=\"description\" content=\"Client:\u00a0IQVIA Solutions Canada Inc. 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