{"id":7601,"date":"2017-07-25T00:00:00","date_gmt":"2017-07-25T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/news-releases\/people-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease\/"},"modified":"2023-06-14T18:15:12","modified_gmt":"2023-06-14T22:15:12","slug":"people-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease","status":"publish","type":"news_release","link":"https:\/\/www.ices.on.ca\/fr\/news-releases\/people-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease\/","title":{"rendered":"People living in rural households have lower risk of developing inflammatory bowel disease"},"content":{"rendered":"<p>Living in rural households decreases a person&#x2019;s risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at the<span class=\"bold\">Institute for Clinical Evaluative Sciences (ICES)<\/span>, Children&apos;s Hospital of Eastern Ontario (CHEO) Research Institute and the Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC).<\/p>\n<div>\n<div class=\"download-section alignwide infographic-download\" id=\"block_60fdeb3528793bfc79a6aedb44b89d6f\" data-style=\"deep-blue\">\n\t<div class=\"download-section-content\">\n\t\t\t\t<h2>\n\t\t\tInfographic\t\t<\/h2>\n\t\t\n\t\t\t<\/div>\n\t<div class=\"download-section-buttons\">\n\t\t\t\t\t\t<a class=\"download-section-buttons-primary\" href=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/03\/BenchimolRuralIBDFIN.jpg\" target=\"_blank\"\n\t\t\tdownload\t\t\taria-label=\"Download Infographic (opens in a new tab)\"\t\t>\n\t\t\tDownload Infographic\t\t\t<svg width=\"19\" height=\"19\" viewBox=\"0 0 19 19\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"presentation\">\n<path d=\"M2.78003 18.8301C2.14282 18.8301 1.59713 18.603 1.14297 18.1488C0.688813 17.6947 0.46212 17.1494 0.462893 16.5129V13.0372H2.78003V16.5129H16.6829V13.0372H19V16.5129C19 17.1502 18.7729 17.6958 18.3188 18.15C17.8646 18.6042 17.3193 18.8308 16.6829 18.8301H2.78003ZM9.73145 14.1958L3.9386 8.40295L5.5606 6.72303L8.57288 9.73531V0.292969H10.89V9.73531L13.9023 6.72303L15.5243 8.40295L9.73145 14.1958Z\" fill=\"#151D5D\"\/>\n<\/svg>\n\t\t<\/a>\n\t\t\n\t\t\t\t\t\t\t\t\t\t<button type=\"button\" class=\"download-section-buttons-secondary\" data-infographic-popup-open=\"block_60fdeb3528793bfc79a6aedb44b89d6f-infographic-popup\" aria-haspopup=\"dialog\">\n\t\t\t\tClick to View\t\t\t<\/button>\n\t\t\t\t\t\t<\/div>\n\n\t\t<div class=\"infographic-popup\" id=\"block_60fdeb3528793bfc79a6aedb44b89d6f-infographic-popup\" role=\"dialog\" aria-modal=\"true\" aria-label=\"Infographic\" hidden>\n\t\t<div class=\"infographic-popup-overlay\" data-infographic-popup-close><\/div>\n\t\t<div class=\"infographic-popup-container\">\n\t\t\t<button type=\"button\" class=\"infographic-popup-close\" data-infographic-popup-close aria-label=\"Close infographic\">&times;<\/button>\n\t\t\t<img decoding=\"async\" class=\"infographic-popup-image\" src=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/03\/BenchimolRuralIBDFIN.jpg\" alt=\"Infographic\">\n\t\t<\/div>\n\t<\/div>\n\t<\/div>\n<\/div>\n<p>&#x201c;Our findings show that children, particularly those under the age of 10, experience a protective effect against IBD if they live in a rural household. This effect is particularly strong in children who are raised in a rural household in the first five years of life. These are important findings since our <a href=\"\/publications\/journal-articles\/trends-in-epidemiology-of-pediatric-inflammatory-bowel-disease-in-canada-distributed-network-analysis-of-multiple-population-based-provincial-health-administrative-databases\/\">previous work<\/a> shows that the number of very young children being diagnosed with IBD has jumped in the past 20 years,&#x201d; says <a href=\"\/ices-scientists\/eric-benchimol\/\">Dr. Eric Benchimol<\/a>, lead author of the study, scientist at ICES and a pediatric gastroenterologist at the Children&apos;s Hospital of Eastern Ontario Inflammatory Bowel Disease Centre, in Ottawa. &#x201c;The findings also strengthen our understanding that environmental risk factors that predispose people to IBD may have a stronger effect in children than adults.&#x201d;<\/p>\n<p>IBD primarily includes Crohn&#x2019;s disease and ulcerative colitis, which are lifelong conditions that cause inflammation in the digestive tract, leading to chronic diarrhea, blood in the stool, abdominal pains and weight loss.<\/p>\n<p>The study published today in the <em>American Journal of Gastroenterology<\/em>, identified a total of 45,567 patients diagnosed with IBD; 6,662 of those patients diagnosed with IBD were living in rural residences and 38,905 were living in urban residences from 1999 to 2010 in four Canadian provinces (Alberta, Manitoba, Nova Scotia and Ontario). The overall incidence of IBD was 30.72 per 100,000 person-years in the rural population compared with 33.16 per 100,000 in the urban population.<\/p>\n<p>&#x201c;We&#x2019;ve known that in addition to genetic risk factors, environmental factors have been associated with the risk of developing IBD. But this new study demonstrates the importance of early life exposure in altering the risk of IBD, and that needs further study,&#x201d; says Benchimol.<\/p>\n<p>There are approximately 233,000 people living with IBD in Canada, which has one of the highest rates of these immune-mediated diseases in the world. Rates are rising in Canada, particularly in very young children. The reason is not certain, but increased urbanization may play a role. The researchers suggest that living in a rural or urban environment may change the intestinal microbiome, due to different exposures early in life, resulting in decreased or increased risk<\/p>\n<p>&#x201c;Canada has one of the highest rates of IBD in the world, with most cases diagnosed in individuals between the ages of 15 and 30, and an increasing incidence seen in children under the age of 10 &#x201d; said Mina Mawani, president and CEO of Crohn&#x2019;s and Colitis Canada. &#x201c;We are happy to partner and collaborate with CanGIEC in the effort to better understand these diseases. The results of this study provide additional knowledge of the risk factors associated with a diagnosis of Crohn&apos;s disease or ulcerative colitis.&quot;<\/p>\n<p>&#x201c;Rural and urban residence during early life is associated with a lower risk of inflammatory bowel disease: a population-based inception and birth cohort study,&#x201d; was published today in the <em>American Journal of Gastorenterology.<\/em><\/p>\n<p><em>Author block: Benchimol EI, Kaplan GG, Otley AR, Nguyen GC, Underwood FE, Guttmann A, Jones JL, Potter BK, Catley CA, Nugent Z, Cui Y, Tanyingoh D, Mojaverian N, Bitton A, Carroll MW, deBruyn J, Dummer TJB, El-Matary W, Griffiths AM, Jacobson K, Kuenzig ME, Leddin D, Lix LM, Mack DR, Murthy S, S&#xe1;nchez JNP, Singh H, Targownik L, Vutcovici M, Bernstein CN.<\/em><\/p>\n<p><em><span style=\"color: #002060;\"><span class=\"bold\">The Institute for Clinical Evaluative Sciences (ICES)<\/span> is an independent, non-profit organization that uses population-based health information to produce knowledge on a broad range of healthcare issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting healthcare needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad, and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on Twitter: <a href=\"http:\/\/www.twitter.com\/icesontario\" title=\"Twitter link \">@ICESOntario<\/a><\/span><\/em><\/p>\n<p>The CHEO Research Institute coordinates the research activities of the Children&#x2019;s Hospital of Eastern Ontario (CHEO) and is affiliated with the University of Ottawa. Its three programs of research include molecular biomedicine, health information technology, and evidence to practice research; key research themes include cancer, diabetes, obesity, mental health, emergency medicine, musculoskeletal health, electronic health information and privacy, and genetics of rare disease. The CHEO Research Institute makes discoveries today for healthier kids tomorrow. For more information, visit <a href=\"http:\/\/www.cheori.org\/\">www.cheori.org<\/a>. For the latest CHEO news, our Twitter handle is <a href=\"https:\/\/www.instagram.com\/cheohospital\/\" title=\"Opens external link\">@CHEOhospital<\/a><\/p>\n<p>The Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC) is a pan-Canadian network of clinicians, researchers and methodologists that work together to provide the evidence required to improve outcomes and healthcare services for Canadians with inflammatory bowel disease (IBD) using population-level data. For more information, visit www.cangiec.ca.<\/p>\n<h2>FOR FURTHER INFORMATION PLEASE CONTACT:<\/h2>\n<p>Deborah Creatura<br \/>\nMedia Advisor, ICES<strong><\/strong><br \/>\n<a href=\"mailto:deborah.creatura@ices.on.ca\">deborah.creatura@ices.on.ca<\/a><br \/>\n(o) 416-480-4780 or (c) 647-406-5996<\/p>\n<p>Adrienne Vienneau <br \/>\nCommunications, CHEO Research Institute<br \/>\n<a href=\"mailto:avienneau@cheo.on.ca\">avienneau@cheo.on.ca<\/a><br \/>\n(o) 613-737-7600 x4144 or (c) 613-513-8437 <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Living in rural households decreases a person&#x2019;s risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at theInstitute for Clinical Evaluative Sciences (ICES), Children&apos;s Hospital of Eastern Ontario (CHEO) Research Institute and the Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC). &#x201c;Our findings show that children, particularly [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[16,53,48],"class_list":["post-7601","news_release","type-news_release","status-publish","hentry","topic-children-and-young-people","topic-environmental-health","topic-gastroenterology"],"acf":{"infographic":[9429],"journal_article":[3775],"research_report":[],"atlas":[],"research_program":[6740],"site":[6734],"ices_scientist":[1174],"announce_or_event":[],"video":[],"iitn_type":false,"iitn_title":"Rural residents at lower risk of inflammatory bowel disease","iitn_short_title":"","iitn_source_link_url":"http:\/\/www.cbc.ca\/news\/canada\/ottawa\/rural-residents-inflammatory-bowel-disease-study-1.4220907","iitn_source_link_text":"CBC","sitecore_item_id":"6D1EDB95-D7BD-4684-AD7C-554BBC344068","sitecore_item_name":"People-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease-study","sitecore_field_values":"{\n  \"Content\": \"<p>Living in rural households decreases a person&rsquo;s risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at the<span class=\"bold\">Institute for Clinical Evaluative Sciences (ICES)<\/span>, Children's Hospital of Eastern Ontario (CHEO) Research Institute and the Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC).<\/p>n<p><a href=\"~\/media\/5D3D240902EE43CBA98DD6A0A304F7A5.ashx\" onclick=\"_gaq.push(['_trackEvent','Download', 'BenchimolIBDInfographicJuly2017',this.href]);\"><img height=\"203\" alt=\"Rural-dwelling Canadians have lower rates of inflammatory bowel disease\" width=\"350\" src=\"~\/media\/35C0D0504CC948F8B509249C37EE78E4.ashx\" \/><\/a><span class=\"grey\" style=\"font-size: 12px; font-weight: bold; display: block; color: #5b5656;\">Click image to enlarge<\/span><\/p>n<p>&ldquo;Our findings show that children, particularly those under the age of 10, experience a protective effect against IBD if they live in a rural household. This effect is particularly strong in children who are raised in a rural household in the first five years of life. These are important findings since our <a href=\"~\/link.aspx?_id=3C3BFB0D388A46A4BDB068B6A7400C5C&amp;_z=z\">previous work<\/a> shows that the number of very young children being diagnosed with IBD has jumped in the past 20 years,&rdquo; says <a href=\"~\/link.aspx?_id=85C78233ED4742C4BF65524CF15A8219&amp;_z=z\">Dr. Eric Benchimol<\/a>, lead author of the study, scientist at ICES and a pediatric gastroenterologist at the Children's Hospital of Eastern Ontario Inflammatory Bowel Disease Centre, in Ottawa. &ldquo;The findings also strengthen our understanding that environmental risk factors that predispose people to IBD may have a stronger effect in children than adults.&rdquo;<\/p>n<p>IBD primarily includes Crohn&rsquo;s disease and ulcerative colitis, which are lifelong conditions that cause inflammation in the digestive tract, leading to chronic diarrhea, blood in the stool, abdominal pains and weight loss.<\/p>n<p>The study published today in the <em>American Journal of Gastroenterology<\/em>, identified a total of 45,567 patients diagnosed with IBD; 6,662 of those patients diagnosed with IBD were living in rural residences and 38,905 were living in urban residences from 1999 to 2010 in four Canadian provinces (Alberta, Manitoba, Nova Scotia and Ontario). The overall incidence of IBD was 30.72 per 100,000 person-years in the rural population compared with 33.16 per 100,000 in the urban population.<\/p>n<p>&ldquo;We&rsquo;ve known that in addition to genetic risk factors, environmental factors have been associated with the risk of developing IBD. But this new study demonstrates the importance of early life exposure in altering the risk of IBD, and that needs further study,&rdquo; says Benchimol.<\/p>n<p>There are approximately 233,000 people living with IBD in Canada, which has one of the highest rates of these immune-mediated diseases in the world. Rates are rising in Canada, particularly in very young children. The reason is not certain, but increased urbanization may play a role. The researchers suggest that living in a rural or urban environment may change the intestinal microbiome, due to different exposures early in life, resulting in decreased or increased risk<\/p>n<p>&ldquo;Canada has one of the highest rates of IBD in the world, with most cases diagnosed in individuals between the ages of 15 and 30, and an increasing incidence seen in children under the age of 10 &rdquo; said Mina Mawani, president and CEO of Crohn&rsquo;s and Colitis Canada. &ldquo;We are happy to partner and collaborate with CanGIEC in the effort to better understand these diseases. The results of this study provide additional knowledge of the risk factors associated with a diagnosis of Crohn's disease or ulcerative colitis.\"<\/p>n<p>&ldquo;Rural and urban residence during early life is associated with a lower risk of inflammatory bowel disease: a population-based inception and birth cohort study,&rdquo; was published today in the <em>American Journal of Gastorenterology.<\/em><\/p>n<p><em>Author block: Benchimol EI, Kaplan GG, Otley AR, Nguyen GC, Underwood FE, Guttmann A, Jones JL, Potter BK, Catley CA, Nugent Z, Cui Y, Tanyingoh D, Mojaverian N, Bitton A, Carroll MW, deBruyn J, Dummer TJB, El-Matary W, Griffiths AM, Jacobson K, Kuenzig ME, Leddin D, Lix LM, Mack DR, Murthy S, S&aacute;nchez JNP, Singh H, Targownik L, Vutcovici M, Bernstein CN.<\/em><\/p>n<p><em><span style=\"color: #002060;\"><span class=\"bold\">The Institute for Clinical Evaluative Sciences (ICES)<\/span> is an independent, non-profit organization that uses population-based health information to produce knowledge on a broad range of healthcare issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting healthcare needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad, and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on Twitter: <a href=\"http:\/\/www.twitter.com\/icesontario\" title=\"Twitter link \">@ICESOntario<\/a><\/span><\/em><\/p>n<p>The CHEO Research Institute coordinates the research activities of the Children&rsquo;s Hospital of Eastern Ontario (CHEO) and is affiliated with the University of Ottawa. Its three programs of research include molecular biomedicine, health information technology, and evidence to practice research; key research themes include cancer, diabetes, obesity, mental health, emergency medicine, musculoskeletal health, electronic health information and privacy, and genetics of rare disease. The CHEO Research Institute makes discoveries today for healthier kids tomorrow. For more information, visit <a href=\"http:\/\/www.cheori.org\/\">www.cheori.org<\/a>. For the latest CHEO news, our Twitter handle is <a href=\"https:\/\/www.instagram.com\/cheohospital\/\" title=\"Opens external link\">@CHEOhospital<\/a><\/p>n<p>The Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC) is a pan-Canadian network of clinicians, researchers and methodologists that work together to provide the evidence required to improve outcomes and healthcare services for Canadians with inflammatory bowel disease (IBD) using population-level data. For more information, visit www.cangiec.ca.<\/p>n<h2>FOR FURTHER INFORMATION PLEASE CONTACT:<\/h2>n<p>Deborah Creatura<br \/>nMedia Advisor, ICES<strong><\/strong><br \/>n<a href=\"mailto:deborah.creatura@ices.on.ca\">deborah.creatura@ices.on.ca<\/a><br \/>n(o) 416-480-4780 or (c) 647-406-5996<\/p>n<p>Adrienne Vienneau <br \/>nCommunications, CHEO Research Institute<br \/>n<a href=\"mailto:avienneau@cheo.on.ca\">avienneau@cheo.on.ca<\/a><br \/>n(o) 613-737-7600 x4144 or (c) 613-513-8437 <\/p>\",\n  \"Title\": \"People living in rural households have lower risk of developing inflammatory bowel disease\",\n  \"Short title\": \"People living in rural households\",\n  \"Teaser image\": \"<image mediaid=\"{A322F4BD-074D-4BD9-A21A-A9A358DE2CFF}\" alt=\"&quot;&quot;\" height=\"\" width=\"\" hspace=\"\" vspace=\"\" \/>\",\n  \"Summary\": \"Living in rural households decreases a person\u2019s risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents.\",\n  \"Location\": \"Toronto\",\n  \"In The News\": \"{B98BACAB-02F8-4228-8011-BA3E639AFE57}\",\n  \"ICES Scientists\": \"{85C78233-ED47-42C4-BF65-524CF15A8219}\",\n  \"ICES Locations\": \"{0AD77E2C-C883-4E93-8B9A-40B82D50E3A5}\",\n  \"Research Programs\": \"{46DF28D2-EDE8-4DF2-8CC0-87CEF464E435}\",\n  \"Posted Date\": \"20170725T080000\",\n  \"Publication Link\": \"<link id=\"{C54FBB9D-422D-40B6-84CE-F4AA429153D0}\" querystring=\"\" text=\"Abstract\" url=\"\/ICES\/Home\/Publications\/Journal-Articles\/2017\/July\/Rural-and-urban-residence-during-early-life-is-associated-with-a-lower-risk-of-inflammatory-bowel\" linktype=\"internal\" target=\"\" \/>\",\n  \"Related Link\": \"<link text=\"ICES in the News | CBC\" linktype=\"external\" url=\"http:\/\/www.cbc.ca\/news\/canada\/ottawa\/rural-residents-inflammatory-bowel-disease-study-1.4220907\" anchor=\"\" title=\"Opens external link\" target=\"\" \/>\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Newsroom\/News-Releases\/2017\/People-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease-study"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | People living in rural households have lower risk of developing inflammatory bowel disease<\/title>\n<meta name=\"description\" content=\"Living in rural households decreases a person&#x2019;s risk of developing inflammatory bowel disease (IBD), particularly for young children and\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/news-releases\/people-living-in-rural-households-have-lower-risk-of-developing-inflammatory-bowel-disease\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" 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