{"id":7568,"date":"2017-02-20T00:00:00","date_gmt":"2017-02-20T05:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/news-releases\/young-children-of-mothers-prescribed-opioids-at-increased-risk-of-overdose\/"},"modified":"2023-06-14T18:14:28","modified_gmt":"2023-06-14T22:14:28","slug":"young-children-of-mothers-prescribed-opioids-at-increased-risk-of-overdose","status":"publish","type":"news_release","link":"https:\/\/www.ices.on.ca\/fr\/news-releases\/young-children-of-mothers-prescribed-opioids-at-increased-risk-of-overdose\/","title":{"rendered":"Young children of mothers prescribed opioids at increased risk of overdose"},"content":{"rendered":"<p>Children of women prescribed an opioid painkiller face a nearly 2.5-fold higher risk of being hospitalized for opioid overdose than children whose mothers don&#x2019;t receive these drugs, according to a new study from the <span class=\"bold\">Institute for Clinical Evaluative Sciences (ICES)<\/span> and The Hospital for Sick Children (SickKids).<\/p>\n<p>The dramatic increase in the prescribing of opioids such as codeine and oxycodone over the past two decades in North America has been associated with a marked increase in fatal overdoses. New research shows that young children of women prescribed these painkillers are also at risk of opioid overdose.<\/p>\n<p>&#x201c;With the increase in opioid prescribing and availability of these drugs in North American homes, &#xa0;it&apos;s critical to understand how this may impact children,&#x201d; says Dr. Yaron Finkelstein, lead author of the study, staff physician in Paediatric Emergency Medicine, and Clinical Pharmacology and Toxicology, associate scientist at SickKids. &#x201c;Prescribers, pharmacists and parents should be cognizant of this risk and take measures to prevent overdoses, such as dispensing smaller opioid quantities, considering alternatives to opioids for pain relief, and emphasizing the importance of secure storage and disposal of unused opioids.&#x201d;<\/p>\n<div>\n<div class=\"download-section alignwide infographic-download\" id=\"block_9d5ca291ba0debc02fb02f8352ef13af\" data-style=\"deep-blue\">\n\t<div class=\"download-section-content\">\n\t\t\t\t<h2>\n\t\t\tInfographic\t\t<\/h2>\n\t\t\n\t\t\t<\/div>\n\t<div class=\"download-section-buttons\">\n\t\t\t\t\t\t<a class=\"download-section-buttons-primary\" href=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/03\/FinkelsteinPediatricOverdoseFIN.jpg\" target=\"_blank\"\n\t\t\tdownload\t\t\taria-label=\"Download Infographic (opens in a new tab)\"\t\t>\n\t\t\tDownload Infographic\t\t\t<svg width=\"19\" height=\"19\" viewBox=\"0 0 19 19\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"presentation\">\n<path d=\"M2.78003 18.8301C2.14282 18.8301 1.59713 18.603 1.14297 18.1488C0.688813 17.6947 0.46212 17.1494 0.462893 16.5129V13.0372H2.78003V16.5129H16.6829V13.0372H19V16.5129C19 17.1502 18.7729 17.6958 18.3188 18.15C17.8646 18.6042 17.3193 18.8308 16.6829 18.8301H2.78003ZM9.73145 14.1958L3.9386 8.40295L5.5606 6.72303L8.57288 9.73531V0.292969H10.89V9.73531L13.9023 6.72303L15.5243 8.40295L9.73145 14.1958Z\" fill=\"#151D5D\"\/>\n<\/svg>\n\t\t<\/a>\n\t\t\n\t\t\t\t\t\t\t\t\t\t<button type=\"button\" class=\"download-section-buttons-secondary\" data-infographic-popup-open=\"block_9d5ca291ba0debc02fb02f8352ef13af-infographic-popup\" aria-haspopup=\"dialog\">\n\t\t\t\tClick to View\t\t\t<\/button>\n\t\t\t\t\t\t<\/div>\n\n\t\t<div class=\"infographic-popup\" id=\"block_9d5ca291ba0debc02fb02f8352ef13af-infographic-popup\" role=\"dialog\" aria-modal=\"true\" aria-label=\"Infographic\" hidden>\n\t\t<div class=\"infographic-popup-overlay\" data-infographic-popup-close><\/div>\n\t\t<div class=\"infographic-popup-container\">\n\t\t\t<button type=\"button\" class=\"infographic-popup-close\" data-infographic-popup-close aria-label=\"Close infographic\">&times;<\/button>\n\t\t\t<img decoding=\"async\" class=\"infographic-popup-image\" src=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/03\/FinkelsteinPediatricOverdoseFIN.jpg\" alt=\"Infographic\">\n\t\t<\/div>\n\t<\/div>\n\t<\/div>\n<\/div>\n<p>In the study, published today in <i>Pediatrics<\/i>, the researchers looked at children under age 10 whose mothers&#x2019; prescriptions were covered under Ontario&#x2019;s publicly-funded provincial drug plan and who were treated in the emergency department, hospitalized or died of opioid overdose between 2002 and 2015.&#xa0;They found that young children are at a nearly 2.5-fold risk of severe overdose, often resulting in hospital stays, if their mothers were prescribed opioid medications, compared with those whose mothers were prescribed non-opioid medications for pain.&#xa0; Information about opioid prescription to fathers was not available and could not be included in the study.<\/p>\n<p>The researchers identified 103 children who were 10-years-old or younger with an opioid overdose and 412 children with no opioid overdose, and compared the likelihood that their mothers received an opioid or a non-steroidal anti-inflammatory drug such as ibuprofen before the overdose episode. Half of the children who presented to hospital with an opioid overdose were two-years-old or younger, and one in 10 of the overdoses involved infants younger than 12 months. Nearly 40 per cent of the children were admitted to hospital, including 13 who were treated in critical care units.<\/p>\n<p>&#x201c;For some opioids, a single tablet is enough to kill a child,&#x201d; says <a href=\"\/ices-scientists\/david-juurlink\/\">Dr. David Juurlink<\/a>, study author and senior scientist at ICES. &#x201c;It&#x2019;s important that parents and grandparents understand the importance of keeping these drugs out of the hands of young children.&#x201d;<\/p>\n<p>&#x201c;Overdose risk in young children of women prescribed opioids,&#x201d; was published today in <i>Pediatrics.<\/i><\/p>\n<p><i>Author block: <\/i><i>Yaron Finkelstein, Erin M. Macdonald, Alejandro Gonzalez, Marco LA Sivilotti, Muhammad M. Mamdani, and David N. Juurlink, for the Canadian Drug Safety and Effectiveness Research Network (CDSERN).<\/i><\/p>\n<p>This project is an example of how SickKids and ICES are contributing to making Ontario Healthier, Wealthier and Smarter <a href=\"http:\/\/www.healthierwealthiersmarter.ca\" title=\"External link opens in new window\" target=\"_blank\" rel=\"noopener\">www.healthierwealthiersmarter.ca.<\/a><\/p>\n<p><em><span style=\"color: #002060;\"><span class=\"bold\">The Institute for Clinical Evaluative Sciences (ICES)<\/span> is an independent, non-profit organization that uses population-based health information to produce knowledge on a broad range of healthcare issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting healthcare needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad, and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on Twitter: <a href=\"http:\/\/www.twitter.com\/icesontario\" title=\"Twitter link opens in new window\" target=\"_blank\" rel=\"noopener\">@ICESOntario<\/a><\/span><\/em><\/p>\n<p><b>The Hospital for Sick Children (SickKids)<\/b> is recognized as one of the world&#x2019;s foremost paediatric health-care institutions and is Canada&#x2019;s leading centre dedicated to advancing children&#x2019;s health through the integration of patient care, research and education. Founded in 1875 and affiliated with the University of Toronto, SickKids is one of Canada&#x2019;s most research-intensive hospitals and has generated discoveries that have helped children globally. Its mission is to provide the best in complex and specialized child and family-centred care; pioneer scientific and clinical advancements; share expertise; foster an academic environment that nurtures health-care professionals; and champion an accessible, comprehensive and sustainable child health system. SickKids is proud of its vision for <i>Healthier Children. A Better World<\/i>. For more information, please visit <a href=\"http:\/\/www.sickkids.ca\/\" title=\"External link opens in new window\" target=\"_blank\" rel=\"noopener\">www.sickkids.ca<\/a>. Follow us on Twitter <a href=\"https:\/\/twitter.com\/SickKidsNews\" title=\"Link opens in new window\" target=\"_blank\" rel=\"noopener\">(@SickKidsNews<\/a>) and Instagram (<a href=\"https:\/\/www.instagram.com\/sickkidstoronto\" title=\"Link opens in new window\" target=\"_blank\" rel=\"noopener\">@SickKidsToronto<\/a>).<\/p>\n<h2>FOR FURTHER INFORMATION PLEASE CONTACT:<i><\/i><\/h2>\n<p>Deborah Creatura<br \/>\nMedia Advisor, ICES<br \/>\n<a href=\"mailto:deborah.creatura@ices.on.ca\">deborah.creatura@ices.on.ca<\/a><br \/>\n(o) 416-480-4780 or (c) 647-406-5996<\/p>\n<p>Suzanne Gold<br \/>\nThe Hospital for Sick Children (SickKids)<br \/>\n<a href=\"mailto:suzanne.gold@sickkids.ca\">suzanne.gold@sickkids.ca<\/a><br \/>\n416-813-7654, ext. 202059<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Children of women prescribed an opioid painkiller face a nearly 2.5-fold higher risk of being hospitalized for opioid overdose than children whose mothers don&#x2019;t receive these drugs, according to a new study from the Institute for Clinical Evaluative Sciences (ICES) and The Hospital for Sick Children (SickKids). The dramatic increase in the prescribing of opioids [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[16,57,53,26,56,31,21],"class_list":["post-7568","news_release","type-news_release","status-publish","hentry","topic-children-and-young-people","topic-diet-and-nutrition","topic-environmental-health","topic-maternity-and-neonatal-care","topic-pharmacoepidemiology-and-drug-safety","topic-pharmacy","topic-women-or-gender-based-research"],"acf":{"infographic":[9406],"journal_article":[3610],"research_report":[],"atlas":[],"research_program":[6746],"site":[6733],"ices_scientist":[1282],"announce_or_event":[],"video":[],"iitn_type":false,"iitn_title":"Children at higher risk of overdose if mom is prescribed opioids: study","iitn_short_title":"","iitn_source_link_url":"http:\/\/www.theglobeandmail.com\/news\/national\/children-at-higher-risk-of-overdose-if-mom-is-prescribed-opioids-study\/article34088113\/","iitn_source_link_text":"The Globe and Mail","sitecore_item_id":"13222F5C-82FA-4B11-8DF4-3CCAF5234ED6","sitecore_item_name":"Young-children-of-mothers-prescribed-opioids-at-increased-risk-of-overdose","sitecore_field_values":"{\n  \"Content\": \"<p>Children of women prescribed an opioid painkiller face a nearly 2.5-fold higher risk of being hospitalized for opioid overdose than children whose mothers don&rsquo;t receive these drugs, according to a new study from the <span class=\"bold\">Institute for Clinical Evaluative Sciences (ICES)<\/span> and The Hospital for Sick Children (SickKids).<\/p>rn<p>The dramatic increase in the prescribing of opioids such as codeine and oxycodone over the past two decades in North America has been associated with a marked increase in fatal overdoses. New research shows that young children of women prescribed these painkillers are also at risk of opioid overdose.<\/p>rn<p>&ldquo;With the increase in opioid prescribing and availability of these drugs in North American homes, &nbsp;it's critical to understand how this may impact children,&rdquo; says Dr. Yaron Finkelstein, lead author of the study, staff physician in Paediatric Emergency Medicine, and Clinical Pharmacology and Toxicology, associate scientist at SickKids. &ldquo;Prescribers, pharmacists and parents should be cognizant of this risk and take measures to prevent overdoses, such as dispensing smaller opioid quantities, considering alternatives to opioids for pain relief, and emphasizing the importance of secure storage and disposal of unused opioids.&rdquo;<\/p>rn<p><a href=\"~\/media\/8D7BD53BF99A4C70B8602B266F933BE1.ashx\" onclick=\"_gaq.push(['_trackEvent','Download','PediatricOverdoseFinkelsteinInfographicFeb2017',this.href]);\" target=\"_blank\"><img width=\"350\" height=\"231\" alt=\"Household opioid prescriptions increase overdose risk for young children\" src=\"~\/media\/9585626F3B1A477FA1AA8ECAAE2C4C57.ashx\" width=\"350\" height=\"231\" \/><\/a><span class=\"grey\" style=\"font-size: 12px; font-weight: bold; color: #5b5656; display: block;\">Click image to enlarge<\/span><\/p>rn<p>In the study, published today in <i>Pediatrics<\/i>, the researchers looked at children under age 10 whose mothers&rsquo; prescriptions were covered under Ontario&rsquo;s publicly-funded provincial drug plan and who were treated in the emergency department, hospitalized or died of opioid overdose between 2002 and 2015.&nbsp;They found that young children are at a nearly 2.5-fold risk of severe overdose, often resulting in hospital stays, if their mothers were prescribed opioid medications, compared with those whose mothers were prescribed non-opioid medications for pain.&nbsp; Information about opioid prescription to fathers was not available and could not be included in the study.<\/p>rn<p>The researchers identified 103 children who were 10-years-old or younger with an opioid overdose and 412 children with no opioid overdose, and compared the likelihood that their mothers received an opioid or a non-steroidal anti-inflammatory drug such as ibuprofen before the overdose episode. Half of the children who presented to hospital with an opioid overdose were two-years-old or younger, and one in 10 of the overdoses involved infants younger than 12 months. Nearly 40 per cent of the children were admitted to hospital, including 13 who were treated in critical care units.<\/p>rn<p>&ldquo;For some opioids, a single tablet is enough to kill a child,&rdquo; says <a href=\"~\/link.aspx?_id=5268F1B0EB3E457793DF3C70C9399847&amp;_z=z\">Dr. David Juurlink<\/a>, study author and senior scientist at ICES. &ldquo;It&rsquo;s important that parents and grandparents understand the importance of keeping these drugs out of the hands of young children.&rdquo;<\/p>rn<p>&ldquo;Overdose risk in young children of women prescribed opioids,&rdquo; was published today in <i>Pediatrics.<\/i><\/p>rn<p><i>Author block: <\/i><i>Yaron Finkelstein, Erin M. Macdonald, Alejandro Gonzalez, Marco LA Sivilotti, Muhammad M. Mamdani, and David N. Juurlink, for the Canadian Drug Safety and Effectiveness Research Network (CDSERN).<\/i><\/p>rn<p>This project is an example of how SickKids and ICES are contributing to making Ontario Healthier, Wealthier and Smarter <a href=\"http:\/\/www.healthierwealthiersmarter.ca\" title=\"External link opens in new window\" target=\"_blank\">www.healthierwealthiersmarter.ca.<\/a><\/p>rn<p><em><span style=\"color: #002060;\"><span class=\"bold\">The Institute for Clinical Evaluative Sciences (ICES)<\/span> is an independent, non-profit organization that uses population-based health information to produce knowledge on a broad range of healthcare issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting healthcare needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad, and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on Twitter: <a href=\"http:\/\/www.twitter.com\/icesontario\" title=\"Twitter link opens in new window\" target=\"_blank\">@ICESOntario<\/a><\/span><\/em><\/p>rn<p><b>The Hospital for Sick Children (SickKids)<\/b> is recognized as one of the world&rsquo;s foremost paediatric health-care institutions and is Canada&rsquo;s leading centre dedicated to advancing children&rsquo;s health through the integration of patient care, research and education. Founded in 1875 and affiliated with the University of Toronto, SickKids is one of Canada&rsquo;s most research-intensive hospitals and has generated discoveries that have helped children globally. Its mission is to provide the best in complex and specialized child and family-centred care; pioneer scientific and clinical advancements; share expertise; foster an academic environment that nurtures health-care professionals; and champion an accessible, comprehensive and sustainable child health system. SickKids is proud of its vision for <i>Healthier Children. A Better World<\/i>. For more information, please visit <a href=\"http:\/\/www.sickkids.ca\/\" title=\"External link opens in new window\" target=\"_blank\">www.sickkids.ca<\/a>. Follow us on Twitter <a href=\"https:\/\/twitter.com\/SickKidsNews\" title=\"Link opens in new window\" target=\"_blank\">(@SickKidsNews<\/a>) and Instagram (<a href=\"https:\/\/www.instagram.com\/sickkidstoronto\" title=\"Link opens in new window\" target=\"_blank\">@SickKidsToronto<\/a>).<\/p>rn<h2>FOR FURTHER INFORMATION PLEASE CONTACT:<i><\/i><\/h2>rn<p>Deborah Creatura<br \/>rnMedia Advisor, ICES<br \/>rn<a href=\"mailto:deborah.creatura@ices.on.ca\">deborah.creatura@ices.on.ca<\/a><br \/>rn(o) 416-480-4780 or (c) 647-406-5996<\/p>rn<p>Suzanne Gold<br \/>rnThe Hospital for Sick Children (SickKids)<br \/>rn<a href=\"mailto:suzanne.gold@sickkids.ca\">suzanne.gold@sickkids.ca<\/a><br \/>rn416-813-7654, ext. 202059<\/p>\",\n  \"Title\": \"Young children of mothers prescribed opioids at increased risk of overdose\",\n  \"Short title\": \"Young children of mothers prescribed\",\n  \"Teaser image\": \"<image mediaid=\"{A322F4BD-074D-4BD9-A21A-A9A358DE2CFF}\" mediapath=\"\/Images\/ovoid-shape\/ovoid-2\" src=\"~\/media\/A322F4BD074D4BD9A21AA9A358DE2CFF.ashx\" alt=\"publications\" height=\"\" width=\"\" hspace=\"\" vspace=\"\" \/>\",\n  \"Summary\": \"Children of women prescribed an opioid painkiller face a nearly 2.5-fold higher risk of being hospitalized for opioid overdose than children whose mothers don\u2019t receive these drugs.\",\n  \"Location\": \"Toronto\",\n  \"In The News\": \"{D63D0062-3442-46FC-98A1-9B2EA986C4C6}\",\n  \"ICES Scientists\": \"{5268F1B0-EB3E-4577-93DF-3C70C9399847}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"Research Programs\": \"{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}\",\n  \"Related Products\": null,\n  \"Posted Date\": \"20170220T000000\",\n  \"Publication Link\": \"<link text=\"Abstract\" linktype=\"internal\" url=\"\/ICES\/Home\/Publications\/Journal-Articles\/2017\/February\/Overdose-risk-in-young-children-of-women-prescribed-opioids\" querystring=\"\" target=\"\" id=\"{8C5660B5-7E67-406C-9461-8F8D4F66157D}\" \/>\",\n  \"Related Link\": \"<link text=\"ICES in the News | Globe and Mail\" linktype=\"external\" url=\"http:\/\/www.theglobeandmail.com\/news\/national\/children-at-higher-risk-of-overdose-if-mom-is-prescribed-opioids-study\/article34088113\/ \" anchor=\"\" title=\"External link opens in new window\" target=\"_blank\" \/>\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Newsroom\/News-Releases\/2017\/Young-children-of-mothers-prescribed-opioids-at-increased-risk-of-overdose"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Young children of mothers prescribed opioids at increased risk of overdose<\/title>\n<meta name=\"description\" content=\"Children of women prescribed an opioid painkiller face a nearly 2.5-fold higher risk of being hospitalized for opioid overdose than children whose mothers\" \/>\n<meta name=\"robots\" content=\"index, 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