{"id":6730,"date":"2016-07-11T00:00:00","date_gmt":"2016-07-11T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/the-temporal-relationship-between-diabetes-and-cancer-a-population-based-study\/"},"modified":"2023-06-14T19:58:31","modified_gmt":"2023-06-14T23:58:31","slug":"the-temporal-relationship-between-diabetes-and-cancer-a-population-based-study","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/the-temporal-relationship-between-diabetes-and-cancer-a-population-based-study\/","title":{"rendered":"The temporal relationship between diabetes and cancer: a population-based study"},"content":{"rendered":"<p><strong>Background<\/strong> &#x2014; Diabetes is associated with an increased risk of several cancers; however, greater detection of cancer around the time of diabetes diagnosis may partly contribute to this relationship. The goal of the current study was to explore the temporal relationship between diabetes and cancer incidence.<\/p>\n<p><strong>Methods<\/strong> &#x2014; The authors conducted a retrospective, population-based cohort study of &gt;1 million adults living in Ontario, Canada to evaluate the association between diabetes diagnosis and the incidence of cancer in 3 time periods: within the 10 years before a diabetes diagnosis, within the first 3 months after a diabetes diagnosis, and from 3 months to 10 years after a diabetes diagnosis.<\/p>\n<p><strong>Results<\/strong> &#x2014; Individuals with diabetes were significantly more likely to have been diagnosed with cancer within the 10 years before a diabetes diagnosis compared with individuals without diabetes (odds ratio, 1.23; 95% confidence interval [95% CI], 1.19-1.27). Cancer incidence also was found to be significantly higher in individuals with diabetes within the 3-month period after a diabetes diagnosis (hazard ratio, 1.62; 95% CI, 1.52-1.74), whereas the risk was not found to be elevated in the later period (hazard ratio, 0.97; 95% CI, 0.95-0.98). Similar trends were noted for individual cancers.<\/p>\n<p><strong>Conclusions<\/strong> &#x2014; The results demonstrated that individuals with diabetes had a significantly higher risk of most cancers, which was limited to the time periods before and immediately after a diabetes diagnosis. The highest risk period was observed within the first 3 months after a diabetes diagnosis, suggesting a partial role of detection bias in the apparent relationship between diabetes and cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background &#x2014; Diabetes is associated with an increased risk of several cancers; however, greater detection of cancer around the time of diabetes diagnosis may partly contribute to this relationship. The goal of the current study was to explore the temporal relationship between diabetes and cancer incidence. Methods &#x2014; The authors conducted a retrospective, population-based cohort [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[38,50],"migration-helper-qa-sample-set":[],"class_list":["post-6730","journal_article","type-journal_article","status-publish","hentry","topic-cancer-and-cancer-screening","topic-endocrinology"],"acf":{"citation":"Lega IC, Wilton AS, Austin PC, Fischer HD, Johnson JA, Lipscombe LL. <em>Cancer<\/em>. 2016; 122(17):2731-8. Epub 2016 Jul 11.","source_url":"","ices_scientist":[1385,1295,1285],"site":[6735,6733],"research_program":[6742,6746],"news_release":[7645],"journal_article":[],"atlas":[],"research_report":[],"infographic":[9301],"video":[],"downloads":null,"links":null,"sitecore_item_id":"8867C4B4-0A9C-4EB8-B964-B6FA990B2FC9","sitecore_item_name":"The-temporal-relationship-between-diabetes-and-cancer-a-population-based-study","sitecore_field_values":"{\n  \"Title\": \"The temporal relationship between diabetes and cancer: a population-based study\",\n  \"Summary\": \"The goal of the study was to explore the temporal relationship between diabetes and cancer incidence.\",\n  \"Citation\": \"<p>Lega IC, Wilton AS, Austin PC, Fischer HD, Johnson JA, Lipscombe LL. <em>Cancer<\/em>. 2016; 122(17):2731-8. Epub 2016 Jul 11.<\/p>\",\n  \"Abstract\": \"<p><strong>Background<\/strong> &mdash; Diabetes is associated with an increased risk of several cancers; however, greater detection of cancer around the time of diabetes diagnosis may partly contribute to this relationship. The goal of the current study was to explore the temporal relationship between diabetes and cancer incidence.<\/p>rn<p><strong>Methods<\/strong> &mdash; The authors conducted a retrospective, population-based cohort study of &gt;1 million adults living in Ontario, Canada to evaluate the association between diabetes diagnosis and the incidence of cancer in 3 time periods: within the 10 years before a diabetes diagnosis, within the first 3 months after a diabetes diagnosis, and from 3 months to 10 years after a diabetes diagnosis.<\/p>rn<p><strong>Results<\/strong> &mdash; Individuals with diabetes were significantly more likely to have been diagnosed with cancer within the 10 years before a diabetes diagnosis compared with individuals without diabetes (odds ratio, 1.23; 95% confidence interval [95% CI], 1.19-1.27). Cancer incidence also was found to be significantly higher in individuals with diabetes within the 3-month period after a diabetes diagnosis (hazard ratio, 1.62; 95% CI, 1.52-1.74), whereas the risk was not found to be elevated in the later period (hazard ratio, 0.97; 95% CI, 0.95-0.98). Similar trends were noted for individual cancers.<\/p>rn<p><strong>Conclusions<\/strong> &mdash; The results demonstrated that individuals with diabetes had a significantly higher risk of most cancers, which was limited to the time periods before and immediately after a diabetes diagnosis. The highest risk period was observed within the first 3 months after a diabetes diagnosis, suggesting a partial role of detection bias in the apparent relationship between diabetes and cancer.<\/p>\",\n  \"Keywords\": \"{EDACCF0C-A0D0-4496-9216-D3055A23BC38}|{4F321D0E-F7F1-4C8D-B2FE-922AD8DE3C78}|{26EB1DB1-6793-4CB3-9CFB-DFF37E09FB5A}\",\n  \"Related Products\": \"<h2>News Release<\/h2>rn<h3><a href=\"~\/link.aspx?_id=FC4D267279734765972790FCFE50B553&amp;_z=z\">Study of one million patients shows link between type 2 diabetes and many types of cancer<\/a><\/h3>rn<h2>Infographic<\/h2>rn<h3><a href=\"~\/link.aspx?_id=C7B5678E0603488DB4B175FC4453731F&amp;_z=z?year=2016&amp;page=1#diabetesandcancer\">Study of one million patients shows link between type 2 diabetes and many types of cancer<\/a><\/h3>rn<h2>ICES IN THE NEWS<\/h2>rn<h3><a href=\"https:\/\/consumer.healthday.com\/cancer-information-5\/mis-cancer-news-102\/cancer-risk-before-and-after-diabetes-diagnosis-712713.html\" title=\"Opens in new window\" target=\"_blank\">Study suggests type 2 diabetes-cancer link<\/a><\/h3>\",\n  \"Research Programs\": \"{BEC72DE0-BA8C-42B8-ACE5-EE29FFB2CB3B}|{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}\",\n  \"ICES Locations\": \"{FBE2D1B1-C0BA-423F-8D16-39466B6C1424}|{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{7D498E8B-5801-4F9E-AC41-11ED50F3C34E}|{DC2C9ADE-ED70-4834-A8AC-A7271C6E48F5}|{A3F02DC0-F8AB-4534-90F5-16B3339AA3D0}\",\n  \"Posted Date\": \"20160711T120100\",\n  \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2016\/January\/The-temporal-relationship-between-diabetes-and-cancer-a-population-based-study"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | The temporal relationship between diabetes and cancer: a population-based study<\/title>\n<meta name=\"description\" content=\"Background &#x2014; 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