{"id":6182,"date":"2008-09-13T00:00:00","date_gmt":"2008-09-13T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/bleeding-and-perforation-after-outpatient-colonoscopy-and-their-risk-factors-in-usual-clinical-practice\/"},"modified":"2023-06-14T19:53:26","modified_gmt":"2023-06-14T23:53:26","slug":"bleeding-and-perforation-after-outpatient-colonoscopy-and-their-risk-factors-in-usual-clinical-practice","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/bleeding-and-perforation-after-outpatient-colonoscopy-and-their-risk-factors-in-usual-clinical-practice\/","title":{"rendered":"Bleeding and perforation after outpatient colonoscopy and their risk factors in usual clinical practice"},"content":{"rendered":"<p><span class=\"bold\">Background and Aims<\/span> &#x2014; The most widely quoted complication rates for colonoscopy are from case series performed by expert endoscopists. Our objectives were to evaluate the rates of bleeding, perforation, and death associated with outpatient colonoscopy and their risk factors in a population-based study.<\/p>\n<p><strong>Methods<\/strong> &#x2014; We identified all individuals 50 to 75 years old who underwent an outpatient colonoscopy during April 1, 2002, to March 31, 2003, in British Columbia, Alberta, Ontario, and Nova Scotia, Canada. Using administrative data, we identified all individuals who were admitted to hospital with bleeding or perforation within 30 days following the colonoscopy in each province. We calculated the pooled rates of bleeding and perforation from the 4 provinces. In Ontario, we abstracted the hospital charts of all deaths that occurred within 30 days following the procedure. We used generalized estimating equations models to evaluate factors associated with bleeding and perforation.<\/p>\n<p><strong>Results<\/strong> &#x2014; We identified 97,091 persons who had an outpatient colonoscopy. The pooled rates of colonoscopy-related bleeding and perforation were 1.64\/1000 and 0.85\/1000, respectively. The death rate was 0.074\/1000 or approximately 1\/14,000. Older age, male sex, having a polypectomy, and having the colonoscopy performed by a low-volume endoscopist were associated with increased odds of bleeding or perforation.<\/p>\n<p><strong>Conclusions<\/strong> &#x2014; Although colonoscopy has established benefits for the detection of colorectal cancer and adenomatous polyps, the procedure is associated with risks of serious complications, including death. Older age, male sex, having a polypectomy, and having the procedure done by a low-volume endoscopist were independently associated with colonoscopy-related bleeding and perforation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background and Aims &#x2014; The most widely quoted complication rates for colonoscopy are from case series performed by expert endoscopists. Our objectives were to evaluate the rates of bleeding, perforation, and death associated with outpatient colonoscopy and their risk factors in a population-based study. Methods &#x2014; We identified all individuals 50 to 75 years old [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[38],"migration-helper-qa-sample-set":[],"class_list":["post-6182","journal_article","type-journal_article","status-publish","hentry","topic-cancer-and-cancer-screening"],"acf":{"citation":"Rabeneck L, Paszat LF, Hilsden RJ, Saskin R, Leddin D, Grunfeld E, Wai E, Goldwasser M, Sutradhar R, Stukel TA.<em> Gastroenterology<\/em>. 2008; 135(6):1899-1906. Epub 2008 Sep 13.","source_url":"http:\/\/www.gastrojournal.org\/article\/S0016-5085(08)01673-9\/fulltext","ices_scientist":[1342,1099,1370,1372,1360],"site":[6733],"research_program":[6741,6740],"news_release":[7279],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"87E90FA4-4EDD-46E4-A9A1-A17F6A8A6047","sitecore_item_name":"Bleeding-and-perforation-after-outpatient-colonoscopy-and-their-risk-factors","sitecore_field_values":"{\n  \"Title\": \"Bleeding and perforation after outpatient colonoscopy and their risk factors in usual clinical practice\",\n  \"Short title\": \"Bleeding and perforation after\",\n  \"Citation\": \"<p>Rabeneck L, Paszat LF, Hilsden RJ, Saskin R, Leddin D, Grunfeld E, Wai E, Goldwasser M, Sutradhar R, Stukel TA.<em> Gastroenterology<\/em>. 2008; 135(6):1899-1906. Epub 2008 Sep 13.<\/p>\",\n  \"Abstract\": \"<p><span class=\"bold\">Background and Aims<\/span> &mdash; The most widely quoted complication rates for colonoscopy are from case series performed by expert endoscopists. Our objectives were to evaluate the rates of bleeding, perforation, and death associated with outpatient colonoscopy and their risk factors in a population-based study.<\/p>n<p><strong>Methods<\/strong> &mdash; We identified all individuals 50 to 75 years old who underwent an outpatient colonoscopy during April 1, 2002, to March 31, 2003, in British Columbia, Alberta, Ontario, and Nova Scotia, Canada. Using administrative data, we identified all individuals who were admitted to hospital with bleeding or perforation within 30 days following the colonoscopy in each province. We calculated the pooled rates of bleeding and perforation from the 4 provinces. In Ontario, we abstracted the hospital charts of all deaths that occurred within 30 days following the procedure. We used generalized estimating equations models to evaluate factors associated with bleeding and perforation.<\/p>n<p><strong>Results<\/strong> &mdash; We identified 97,091 persons who had an outpatient colonoscopy. The pooled rates of colonoscopy-related bleeding and perforation were 1.64\/1000 and 0.85\/1000, respectively. The death rate was 0.074\/1000 or approximately 1\/14,000. Older age, male sex, having a polypectomy, and having the colonoscopy performed by a low-volume endoscopist were associated with increased odds of bleeding or perforation.<\/p>n<p><strong>Conclusions<\/strong> &mdash; Although colonoscopy has established benefits for the detection of colorectal cancer and adenomatous polyps, the procedure is associated with risks of serious complications, including death. Older age, male sex, having a polypectomy, and having the procedure done by a low-volume endoscopist were independently associated with colonoscopy-related bleeding and perforation.<\/p>n<p><a href=\"http:\/\/www.gastrojournal.org\/article\/S0016-5085(08)01673-9\/fulltext\" title=\"External link opens\">View full text<\/a><\/p>\",\n  \"Keywords\": \"{98717EF3-BD0D-4962-A644-46468661884A}|{B7EC787E-A528-4EE1-8BF8-487379BE5217}|{EDACCF0C-A0D0-4496-9216-D3055A23BC38}\",\n  \"Related Products\": \"<h2>News Release<\/h2>rn<h3><a href=\"~\/link.aspx?_id=8CE5CF8B7B2F494D883EFF81E230943F&amp;_z=z\">First-ever large-scale study of colonoscopy complications identifies those Canadians at greatest risk from the procedure<\/a><\/h3>\",\n  \"Research Programs\": \"{85DE96A6-4C96-40C7-8E6D-7597A0EB5F80}|{46DF28D2-EDE8-4DF2-8CC0-87CEF464E435}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{D58A8993-4C34-4C55-8F94-717F6C1FDD31}|{F137150D-7BD5-4368-8FCC-FAF6D82891C4}|{8ADC61A9-9EB9-4E91-90E5-6F4E48B97BD5}|{56BF24FA-D81E-4114-BF1F-4715A424E26C}|{A0978F87-1C10-4E62-A833-89616146CA59}|{826B4C0C-81D4-49A9-837F-DB6413A32E7C}\",\n  \"Posted Date\": \"20080913T000000\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2008\/January\/Bleeding-and-perforation-after-outpatient-colonoscopy-and-their-risk-factors"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Bleeding and perforation after outpatient colonoscopy and their risk factors in usual clinical practice<\/title>\n<meta name=\"description\" content=\"Background and Aims &#x2014; The most widely quoted complication rates for colonoscopy are from case series performed by expert endoscopists. 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