{"id":5429,"date":"2002-09-01T00:00:00","date_gmt":"2002-09-01T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/quantification-of-the-risk-of-corticosteroid-induced-diabetes-mellitus-among-the-elderly\/"},"modified":"2023-06-14T20:03:08","modified_gmt":"2023-06-15T00:03:08","slug":"quantification-of-the-risk-of-corticosteroid-induced-diabetes-mellitus-among-the-elderly","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/quantification-of-the-risk-of-corticosteroid-induced-diabetes-mellitus-among-the-elderly\/","title":{"rendered":"Quantification of the risk of corticosteroid-induced diabetes mellitus among the elderly"},"content":{"rendered":"<p>We conducted a population-based cohort study using administrative databases to quantify the association between oral and inhaled corticosteroid use and onset of diabetes mellitus in the elderly. Proton pump inhibitor (PPI) users were used as a control group. Relative to PPI users (N = 53,845), oral corticosteroid users (N = 31,864) were more likely to develop diabetes (adjusted rate ratio [aRR], 2.31; 95% confidence interval [95% CI], 2.11 to 2.54); however, inhaled corticosteroid users (N = 38,441) were not (aRR, 1.03; 95% CI, 0.93 to 1.14). The estimated number needed to harm for continuous use of oral corticosteroids relative to PPIs over 1, 2, and 3 years of use were 41, 23, and 16, respectively.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We conducted a population-based cohort study using administrative databases to quantify the association between oral and inhaled corticosteroid use and onset of diabetes mellitus in the elderly. Proton pump inhibitor (PPI) users were used as a control group. Relative to PPI users (N = 53,845), oral corticosteroid users (N = 31,864) were more likely to [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[50,17,56],"migration-helper-qa-sample-set":[],"class_list":["post-5429","journal_article","type-journal_article","status-publish","hentry","topic-endocrinology","topic-older-people","topic-pharmacoepidemiology-and-drug-safety"],"acf":{"citation":"Blackburn D, Hux J, Mamdani M. <em>J Gen Intern Med<\/em>. 2002; 17(9):717-20.","source_url":"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1495107\/","ices_scientist":[1268,1325],"site":[6735,6733],"research_program":[6746],"news_release":[],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"E7B34AB4-A0FD-43F6-B808-CBEEB4BC8DC1","sitecore_item_name":"Quantification-of-the-risk-of-corticosteroid-induced-diabetes-mellitus-among-the-elderly","sitecore_field_values":"{\n  \"Title\": \"Quantification of the risk of corticosteroid-induced diabetes mellitus among the elderly\",\n  \"Short title\": \"Quantification of the risk of\",\n  \"Citation\": \"<p>Blackburn D, Hux J, Mamdani M. <em>J Gen Intern Med<\/em>. 2002; 17(9):717-20.<\/p>\",\n  \"Abstract\": \"<p>We conducted a population-based cohort study using administrative databases to quantify the association between oral and inhaled corticosteroid use and onset of diabetes mellitus in the elderly. Proton pump inhibitor (PPI) users were used as a control group. Relative to PPI users (N = 53,845), oral corticosteroid users (N = 31,864) were more likely to develop diabetes (adjusted rate ratio [aRR], 2.31; 95% confidence interval [95% CI], 2.11 to 2.54); however, inhaled corticosteroid users (N = 38,441) were not (aRR, 1.03; 95% CI, 0.93 to 1.14). The estimated number needed to harm for continuous use of oral corticosteroids relative to PPIs over 1, 2, and 3 years of use were 41, 23, and 16, respectively.<\/p>n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1495107\/\" title=\"External link opens\">View full text<\/a><\/p>\",\n  \"Keywords\": \"{26EB1DB1-6793-4CB3-9CFB-DFF37E09FB5A}|{2B682F78-2DBB-4427-B98D-1FF13AE60514}|{AD1C8354-D3A0-4679-8E69-7A79EFFE3607}\",\n  \"Research Programs\": \"{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}\",\n  \"ICES Locations\": \"{FBE2D1B1-C0BA-423F-8D16-39466B6C1424}|{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{4C08D086-0DAC-4164-B8DF-54317B959A2C}|{F2F916BC-2EE9-4C65-BCAB-086ED6BB971A}\",\n  \"Posted Date\": \"20020901T000000\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2002\/January\/Quantification-of-the-risk-of-corticosteroid-induced-diabetes-mellitus-among-the-elderly"},"yoast_head":"<!-- This site is optimized with the 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