Forty-one angina patients with coronary disease were interviewed to examine the correlation between prespecified and individualized weights for disease-specific measures of the effects of angina on the patients' well-being. Modifications of the Canadian Cardiovascular Society (CCS) scale for angina and the Duke Activity Specific Index (DASI) were used to rate functional capacity with prespecified items. Disease-specific utilities based on descriptions of functional status were obtained directly, and again indirectly with different anchoring conditions to control for noncardiac comorbidity. Correlations between the functional-capacity measures and the derived utilities were not strong, ranging from -0.25 (p > 0.1) to -0.35 (p = 0.02). Correlation between the two prespecified measures was higher (r = -0.51 or -0.69, both p < 0.01, for DASI versus CCS graded from walking and stair-climbing, respectively). The direct and indirect disease-specific utility scores were similar (r = 0.92, p < 0.01). The method described provides an approach to measuring disease-specific utilities by adapting existing scales for use in a standard gamble. It confirms that prespecified functional status scores inconsistently reflect patients' valuations of functional states. Further investigation should address whether the observed null effect of comorbidity on disease-specific utilities arose from inadequate coverage of the comorbidity issues in patient interviews or from lack of power given the small size of the feasibility study.<\/p>\n","protected":false},"excerpt":{"rendered":"
Forty-one angina patients with coronary disease were interviewed to examine the correlation between prespecified and individualized weights for disease-specific measures of the effects of angina on the patients' well-being. Modifications of the Canadian Cardiovascular Society (CCS) scale for angina and the Duke Activity Specific Index (DASI) were used to rate functional capacity with prespecified items. […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[40],"migration-helper-qa-sample-set":[],"class_list":["post-4478","journal_article","type-journal_article","status-publish","hentry","topic-cardiovascular-disease"],"acf":{"citation":"Nichol G, Llewellyn-Thomas HA, Thiel EC, Naylor CD. Med Decis Making<\/em>. 1996; 16(1):78-85.","source_url":"","ices_scientist":[1304],"site":[6733],"research_program":[],"news_release":[],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"E96B335E-491A-4ED1-B693-CAA6F4FE026A","sitecore_item_name":"The-relationship-between-cardiac-functional-capacity-and-patients-symptom-specific-utilities","sitecore_field_values":"{\n \"Title\": \"The relationship between cardiac functional capacity and patients' symptom-specific utilities for angina: some findings and methodologic lessons\",\n \"Citation\": \" Nichol G, Llewellyn-Thomas HA, Thiel EC, Naylor CD. Med Decis Making<\/em>. 1996; 16(1):78-85.<\/p>\",\n \"Abstract\": \" Forty-one angina patients with coronary disease were interviewed to examine the correlation between prespecified and individualized weights for disease-specific measures of the effects of angina on the patients' well-being. Modifications of the Canadian Cardiovascular Society (CCS) scale for angina and the Duke Activity Specific Index (DASI) were used to rate functional capacity with prespecified items. Disease-specific utilities based on descriptions of functional status were obtained directly, and again indirectly with different anchoring conditions to control for noncardiac comorbidity. Correlations between the functional-capacity measures and the derived utilities were not strong, ranging from -0.25 (p > 0.1) to -0.35 (p = 0.02). Correlation between the two prespecified measures was higher (r = -0.51 or -0.69, both p < 0.01, for DASI versus CCS graded from walking and stair-climbing, respectively). The direct and indirect disease-specific utility scores were similar (r = 0.92, p < 0.01). The method described provides an approach to measuring disease-specific utilities by adapting existing scales for use in a standard gamble. It confirms that prespecified functional status scores inconsistently reflect patients' valuations of functional states. Further investigation should address whether the observed null effect of comorbidity on disease-specific utilities arose from inadequate coverage of the comorbidity issues in patient interviews or from lack of power given the small size of the feasibility study.<\/p>\",\n \"Keywords\": \"{92E2791D-5DAB-4244-8A85-434D524D9A12}|{4C3C4666-4DC7-433A-A6A3-753D35441055}\",\n \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n \"ICES Scientists\": \"{545C70EB-0A3F-4646-A0F5-509EB7E15CF6}\",\n \"Posted Date\": \"19960101T000000\",\n \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/1996\/January\/The-relationship-between-cardiac-functional-capacity-and-patients-symptom-specific-utilities"},"yoast_head":"\n