Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated with NTM-PD and NTM-PI and differences in survival between them, we conducted a population-based cohort study of persons with microbiologically defined NTM-PD or NTM-PI diagnosed during 2001-2013 in Ontario, Canada. We used propensity score matching and Cox proportional hazards models to compare survival. Among 9,681 NTM-PD patients and 10,936 NTM-PI patients, 87% and 91%, respectively, were successfully matched with unexposed controls. Both NTM-PD and NTM-PI were associated with higher rates of death for all species combined and for most individual species. Compared with NTM-PI, NTM-PD was associated with higher death rates for all species combined, Mycobacterium avium complex, and M. xenopi. NTM-PD and NTM-PI were significantly associated with death, NTM-PD more so than NTM-PI.<\/p>\n","protected":false},"excerpt":{"rendered":"
Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated with NTM-PD and NTM-PI and differences in survival between them, we conducted a population-based cohort study of persons with microbiologically defined NTM-PD or NTM-PI diagnosed during 2001-2013 in Ontario, Canada. We used propensity score […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[39],"migration-helper-qa-sample-set":[],"class_list":["post-3736","journal_article","type-journal_article","status-publish","hentry","topic-infectious-diseases"],"acf":{"citation":"Marras TK, Campitelli MA, Lu H, Chung H, Brode SK, Marchand-Austin A, Winthrop KL, Gershon AS, Kwong JC, Jamieson FB. Emerg Infect Dis<\/em>. 2017; 23(3):468-76.","source_url":"https:\/\/wwwnc.cdc.gov\/eid\/article\/23\/3\/16-1927_article","ices_scientist":[1207,1244,1149,1158],"site":[6733],"research_program":[],"news_release":[],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"686FF6E0-8B6B-4581-BD46-2F465C6B4197","sitecore_item_name":"Pulmonary-nontuberculous-mycobacteria-associated-deaths-Ontario-Canada-2001-2013","sitecore_field_values":"{\n \"Title\": \"Pulmonary nontuberculous mycobacteria-associated deaths, Ontario, Canada, 2001-2013\",\n \"Short title\": \"Pulmonary nontuberculous\",\n \"Summary\": \"This study examined deaths associated with nontuberculous mycobacterial pulmonary disease in Ontario, Canada.\",\n \"Citation\": \"