{"id":3289,"date":"2010-01-28T00:00:00","date_gmt":"2010-01-28T05:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/non-invasive-cardiac-stress-testing-before-elective-major-non-cardiac-surgery-population-based-cohort-study\/"},"modified":"2023-06-14T20:05:03","modified_gmt":"2023-06-15T00:05:03","slug":"non-invasive-cardiac-stress-testing-before-elective-major-non-cardiac-surgery-population-based-cohort-study","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/non-invasive-cardiac-stress-testing-before-elective-major-non-cardiac-surgery-population-based-cohort-study\/","title":{"rendered":"Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study"},"content":{"rendered":"<p><strong>Objective<\/strong> &#x2014; To determine the association of non-invasive cardiac stress testing before elective intermediate to high risk non-cardiac surgery with survival and hospital stay.<\/p>\n<p><strong>Design<\/strong> &#x2014; Population based retrospective cohort study.<\/p>\n<p><strong>Setting<\/strong> &#x2014; Acute care hospitals in Ontario, Canada, between 1 April 1994 and 31 March 2004.<\/p>\n<p><strong>Participants<\/strong> &#x2014; Patients aged 40 years or older who underwent specific elective intermediate to high risk non-cardiac surgical procedures.<\/p>\n<p><strong>Interventions<\/strong> &#x2014; Non-invasive cardiac stress testing performed within six months before surgery.<\/p>\n<p><strong>Main Outcome Measures<\/strong> &#x2014; Postoperative one year survival and length of stay in hospital.<\/p>\n<p><strong>Results<\/strong> &#x2014; Of the 271 082 patients in the entire cohort, 23 991 (8.9%) underwent stress testing. After propensity score methods were used to reduce important differences between patients who did or did not undergo preoperative stress testing and assemble a matched cohort (n=46 120), testing was associated with improved one year survival (hazard ratio (HR) 0.92, 95% CI 0.86 to 0.99; P=0.03) and reduced mean hospital stay (difference -0.24 days, 95% CI -0.07 to -0.43; P&lt;0.001). In an analysis of subgroups defined by Revised Cardiac Risk Index (RCRI) class, testing was associated with harm in low risk patients (RCRI 0 points: HR 1.35, 95% CI 1.05 to 1.74), but with benefit in patients who were at intermediate risk (RCRI 1-2 points: 0.92, 95% CI 0.85 to 0.99) or high risk (RCRI 3-6 points: 0.80, 95% CI 0.67 to 0.97).<\/p>\n<p><strong>Conclusions<\/strong> &#x2014; Preoperative non-invasive cardiac stress testing is associated with improved one year survival and length of hospital stay in patients undergoing elective intermediate to high risk non-cardiac surgery. These benefits principally apply to patients with risk factors for perioperative cardiac complications.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective &#x2014; To determine the association of non-invasive cardiac stress testing before elective intermediate to high risk non-cardiac surgery with survival and hospital stay. Design &#x2014; Population based retrospective cohort study. Setting &#x2014; Acute care hospitals in Ontario, Canada, between 1 April 1994 and 31 March 2004. Participants &#x2014; Patients aged 40 years or older [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[40,35,25],"migration-helper-qa-sample-set":[],"class_list":["post-3289","journal_article","type-journal_article","status-publish","hentry","topic-cardiovascular-disease","topic-public-health","topic-surgery"],"acf":{"citation":"Wijeysundera DN, Beattie WS, Austin PC, Hux JE, Laupacis A. <em>BMJ<\/em>. 2010; 340:b5526.","source_url":"http:\/\/www.bmj.com\/content\/340\/bmj.b5526?view=long&pmid=20110306","ices_scientist":[1132,1385,1268,1293],"site":[6733],"research_program":[6742,6746],"news_release":[7767],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"248107BB-5A23-497C-94E7-D4997A588FD9","sitecore_item_name":"Non-invasive-cardiac-stress-testing-before-elective-major-non-cardiac-surgery-population-based","sitecore_field_values":"{\n  \"Title\": \"Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study\",\n  \"Short title\": \"Non-invasive cardiac stress testing\",\n  \"Citation\": \"<p>Wijeysundera DN, Beattie WS, Austin PC, Hux JE, Laupacis A. <em>BMJ<\/em>. 2010; 340:b5526.<\/p>\",\n  \"Abstract\": \"<p><strong>Objective<\/strong> &mdash; To determine the association of non-invasive cardiac stress testing before elective intermediate to high risk non-cardiac surgery with survival and hospital stay.<\/p>n<p><strong>Design<\/strong> &mdash; Population based retrospective cohort study.<\/p>n<p><strong>Setting<\/strong> &mdash; Acute care hospitals in Ontario, Canada, between 1 April 1994 and 31 March 2004.<\/p>n<p><strong>Participants<\/strong> &mdash; Patients aged 40 years or older who underwent specific elective intermediate to high risk non-cardiac surgical procedures.<\/p>n<p><strong>Interventions<\/strong> &mdash; Non-invasive cardiac stress testing performed within six months before surgery.<\/p>n<p><strong>Main Outcome Measures<\/strong> &mdash; Postoperative one year survival and length of stay in hospital.<\/p>n<p><strong>Results<\/strong> &mdash; Of the 271 082 patients in the entire cohort, 23 991 (8.9%) underwent stress testing. After propensity score methods were used to reduce important differences between patients who did or did not undergo preoperative stress testing and assemble a matched cohort (n=46 120), testing was associated with improved one year survival (hazard ratio (HR) 0.92, 95% CI 0.86 to 0.99; P=0.03) and reduced mean hospital stay (difference -0.24 days, 95% CI -0.07 to -0.43; P&lt;0.001). In an analysis of subgroups defined by Revised Cardiac Risk Index (RCRI) class, testing was associated with harm in low risk patients (RCRI 0 points: HR 1.35, 95% CI 1.05 to 1.74), but with benefit in patients who were at intermediate risk (RCRI 1-2 points: 0.92, 95% CI 0.85 to 0.99) or high risk (RCRI 3-6 points: 0.80, 95% CI 0.67 to 0.97).<\/p>n<p><strong>Conclusions<\/strong> &mdash; Preoperative non-invasive cardiac stress testing is associated with improved one year survival and length of hospital stay in patients undergoing elective intermediate to high risk non-cardiac surgery. These benefits principally apply to patients with risk factors for perioperative cardiac complications.<\/p>n<p><a href=\"http:\/\/www.bmj.com\/content\/340\/bmj.b5526?view=long&amp;pmid=20110306\" title=\"External link to full text\">View full text<\/a><\/p>\",\n  \"Keywords\": \"{92E2791D-5DAB-4244-8A85-434D524D9A12}|{9F514AF9-2526-48FE-8414-54C443CF99AD}|{D41CE091-DCDC-475E-9E15-4BC16AEE1D81}\",\n  \"Related Products\": \"<h2>News Release<\/h2>rn<h3><a href=\"~\/link.aspx?_id=F747B2D155D74ECB8D8680D52E519F78&amp;_z=z\">High risk patients less likely to die if they undergo stress testing before surgery but low risk patients may be harmed<\/a><\/h3>\",\n  \"Research Programs\": \"{BEC72DE0-BA8C-42B8-ACE5-EE29FFB2CB3B}|{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{22E01D03-965E-4F09-9CC2-6BC40EC9403D}|{7D498E8B-5801-4F9E-AC41-11ED50F3C34E}|{4C08D086-0DAC-4164-B8DF-54317B959A2C}|{83920C20-06BE-4C6B-9FA7-06B69A509A24}\",\n  \"Posted Date\": \"20100128T000000\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2010\/January\/Non-invasive-cardiac-stress-testing-before-elective-major-non-cardiac-surgery-population-based"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study<\/title>\n<meta name=\"description\" content=\"Objective &#x2014; 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