{"id":3149,"date":"2020-08-18T00:00:00","date_gmt":"2020-08-18T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\/"},"modified":"2023-06-14T19:23:15","modified_gmt":"2023-06-14T23:23:15","slug":"association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\/","title":{"rendered":"Association between bariatric surgery and all-cause mortality: a population-based matched cohort study in a universal healthcare system"},"content":{"rendered":"<p><strong>Background <\/strong>&#x2014; Mortality after bariatric surgery has been previously studied, but cohort selection bias, completeness of follow-up, and collection of confounders have limited the inference of results.<\/p>\n<p><strong>Objective <\/strong>&#x2014; To determine the association between bariatric surgery and all-cause mortality.<\/p>\n<p><strong>Design <\/strong>&#x2014; Population-based matched cohort study.<\/p>\n<p><strong>Setting <\/strong>&#x2014; Ontario, Canada.<\/p>\n<p><strong>Participants <\/strong>&#x2014; 13 679 patients who underwent bariatric surgery from January 2010 to December 2016 and 13 679 matched nonsurgical patients.<\/p>\n<p><strong>Intervention <\/strong>&#x2014; Bariatric surgery.<\/p>\n<p><strong>Measurements <\/strong>&#x2014; The primary outcome was all-cause mortality, with cause-specific mortality as the secondary outcome. Patients were matched according to age, sex, body mass index, and diabetes duration.<\/p>\n<p><strong>Results <\/strong>&#x2014; 13 679 patients who underwent bariatric surgery were matched to 13 679 nonsurgical patients. After a median follow-up of 4.9 years, the overall mortality rate was 1.4% (n = 197) in the surgery group and 2.5% (n = 340) in the nonsurgery group, with a lower adjusted hazard ratio (HR) of overall all-cause mortality (HR, 0.68 [95% CI, 0.57 to 0.81]). Patients aged 55 years or older had an absolute risk reduction of 3.3% (CI, 2.3% to 4.3%), with a lower HR of mortality in the surgery group (HR, 0.53 [CI, 0.41 to 0.69]). Observed relative effects were similar across sex; however, the observed association in absolute terms was greater in men. Surgery also was associated with lower cardiovascular mortality (HR, 0.53 [CI, 0.34 to 0.84]) and lower cancer mortality (HR, 0.54 [CI, 0.36 to 0.80]).<\/p>\n<p><strong>Limitation <\/strong>&#x2014; The observational design limits causal inference.<\/p>\n<p><strong>Conclusion <\/strong>&#x2014; Bariatric surgery was associated with substantially lower all-cause, cardiovascular, and cancer mortality. The lowered observed mortality of surgery was significant across most subgroups. The largest absolute effects were for men and patients aged 55 years or older.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background &#x2014; Mortality after bariatric surgery has been previously studied, but cohort selection bias, completeness of follow-up, and collection of confounders have limited the inference of results. Objective &#x2014; To determine the association between bariatric surgery and all-cause mortality. Design &#x2014; Population-based matched cohort study. Setting &#x2014; Ontario, Canada. Participants &#x2014; 13 679 patients who [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[],"migration-helper-qa-sample-set":[],"class_list":["post-3149","journal_article","type-journal_article","status-publish","hentry"],"acf":{"citation":"Doumouras AG, Hong D, Lee Y, Tarride J, Paterson JM, Anvari M. <em>Ann Intern Med<\/em>. 2020; 173(9):694-703. Epub 2020 Aug 18.","source_url":"https:\/\/doi.org\/10.7326\/M19-3925","ices_scientist":[1100,1257,1209,1376],"site":[6737],"research_program":[6746],"news_release":[],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"14ECE0C9-E9C6-4A78-9343-172F9E064EBF","sitecore_item_name":"Association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort","sitecore_field_values":"{\n  \"Title\": \"Association between bariatric surgery and all-cause mortality: a population-based matched cohort study in a universal healthcare system\",\n  \"Short title\": \"Association between bariatric surgery\",\n  \"Summary\": \"The objective of this study was to determine the association between bariatric surgery and all-cause mortality.\",\n  \"Citation\": \"<p>Doumouras AG, Hong D, Lee Y, Tarride J, Paterson JM, Anvari M. <em>Ann Intern Med<\/em>. 2020; 173(9):694-703. Epub 2020 Aug 18. DOI: <a href=\"https:\/\/doi.org\/10.7326\/M19-3925\" title=\"Opens external link\">https:\/\/doi.org\/10.7326\/M19-3925<\/a><\/p>\",\n  \"Abstract\": \"<p><strong>Background <\/strong>&mdash; Mortality after bariatric surgery has been previously studied, but cohort selection bias, completeness of follow-up, and collection of confounders have limited the inference of results.<\/p>n<p><strong>Objective <\/strong>&mdash; To determine the association between bariatric surgery and all-cause mortality.<\/p>n<p><strong>Design <\/strong>&mdash; Population-based matched cohort study.<\/p>n<p><strong>Setting <\/strong>&mdash; Ontario, Canada.<\/p>n<p><strong>Participants <\/strong>&mdash; 13 679 patients who underwent bariatric surgery from January 2010 to December 2016 and 13 679 matched nonsurgical patients.<\/p>n<p><strong>Intervention <\/strong>&mdash; Bariatric surgery.<\/p>n<p><strong>Measurements <\/strong>&mdash; The primary outcome was all-cause mortality, with cause-specific mortality as the secondary outcome. Patients were matched according to age, sex, body mass index, and diabetes duration.<\/p>n<p><strong>Results <\/strong>&mdash; 13 679 patients who underwent bariatric surgery were matched to 13 679 nonsurgical patients. After a median follow-up of 4.9 years, the overall mortality rate was 1.4% (n = 197) in the surgery group and 2.5% (n = 340) in the nonsurgery group, with a lower adjusted hazard ratio (HR) of overall all-cause mortality (HR, 0.68 [95% CI, 0.57 to 0.81]). Patients aged 55 years or older had an absolute risk reduction of 3.3% (CI, 2.3% to 4.3%), with a lower HR of mortality in the surgery group (HR, 0.53 [CI, 0.41 to 0.69]). Observed relative effects were similar across sex; however, the observed association in absolute terms was greater in men. Surgery also was associated with lower cardiovascular mortality (HR, 0.53 [CI, 0.34 to 0.84]) and lower cancer mortality (HR, 0.54 [CI, 0.36 to 0.80]).<\/p>n<p><strong>Limitation <\/strong>&mdash; The observational design limits causal inference.<\/p>n<p><strong>Conclusion <\/strong>&mdash; Bariatric surgery was associated with substantially lower all-cause, cardiovascular, and cancer mortality. The lowered observed mortality of surgery was significant across most subgroups. The largest absolute effects were for men and patients aged 55 years or older.<\/p>\",\n  \"Research Programs\": \"{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}\",\n  \"ICES Locations\": \"{D88BC40D-6453-47B1-9A95-3AC57728064D}\",\n  \"ICES Scientists\": \"{4A1034A0-5248-46A2-805E-20FBC57B1237}|{A5D3FE82-5E8C-4627-9B2C-3FCDF5720931}|{8565BB6A-1F14-45AC-BB2B-54DF951D37C0}|{4691B7EB-74E3-4E39-B997-17A2A8B30B08}\",\n  \"Posted Date\": \"20200818T000000\",\n  \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2020\/August\/Association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Association between bariatric surgery and all-cause mortality: a population-based matched cohort study in a universal healthcare system<\/title>\n<meta name=\"description\" content=\"Background &#x2014; Mortality after bariatric surgery has been previously studied, but cohort selection bias, completeness of follow-up, and collection of\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | Association between bariatric surgery and all-cause mortality: a population-based matched cohort study in a universal healthcare system\" \/>\n<meta property=\"og:description\" content=\"Background &#x2014; Mortality after bariatric surgery has been previously studied, but cohort selection bias, completeness of follow-up, and collection of\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\/\" \/>\n<meta property=\"og:site_name\" content=\"ICES\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ICESOntario\/\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-14T23:23:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2024\/11\/ic-es-data-discovery-better-health-logo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\\\/\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/association-between-bariatric-surgery-and-all-cause-mortality-a-population-based-matched-cohort-study-in-a-universal-health-care-system\\\/\",\"name\":\"ICES | Association between bariatric surgery and all-cause mortality: a population-based matched cohort study in a universal healthcare system\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#website\"},\"datePublished\":\"2020-08-18T04:00:00+00:00\",\"dateModified\":\"2023-06-14T23:23:15+00:00\",\"description\":\"Background &#x2014; 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