{"id":24412,"date":"2026-07-04T15:48:25","date_gmt":"2026-07-04T19:48:25","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=24412"},"modified":"2026-08-19T15:54:05","modified_gmt":"2026-08-19T19:54:05","slug":"twenty-five-year-single-center-experience-with-aortic-root-replacement-with-a-composite-valve-graft","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/twenty-five-year-single-center-experience-with-aortic-root-replacement-with-a-composite-valve-graft\/","title":{"rendered":"Twenty-five-year single-center experience with aortic root replacement with a composite valve graft"},"content":{"rendered":"<p><strong>Objective<\/strong> \u2014 The study objective was to evaluate the in-hospital and long-term outcomes of aortic root replacement (Bentall procedure) from a single institution.<\/p>\n<p><strong>Methods<\/strong> \u2014 All patients who underwent the Bentall procedure from 1990 to 2014 were included. Aortic valve\u2013sparing root replacement or Ross procedures were excluded. The primary end point was all-cause mortality. The secondary end point was major adverse valve-related events, a composite of death, aortic valve reoperation (surgical or transcatheter), aortic valve endocarditis, major bleeding, and the need for a permanent pacemaker or defibrillator.<\/p>\n<p><strong>Results<\/strong> \u2014 A total of 1332 adults underwent a Bentall procedure during the study period, with 525 (39.4%) undergoing concomitant procedures and 807 (60.6%) undergoing the isolated Bentall. Mean age was 57.6 \u00b1 15.6 years, with 130 patients (9.8%) having endocarditis and 400 patients (30.0%) having a previous cardiac surgery. Isolated aortic insufficiency was present in 600 patients (45%), and a mechanical valve was used in 516 of 1332 patients (38.7%). In-hospital or 30-day death occurred in 65 of 1332 patients (4.9%), which was worse among those undergoing concomitant valve or coronary bypass, 45 of 525 (8.6%) versus 20 of 807 (2.5%) in patients undergoing the isolated Bentall (P &lt; .01). Patients undergoing an elective, first-time isolated Bentall (471 cases) had less than 1% mortality and stroke rates. Overall, 25-year survival was 33.8% (95% CI, 29.9-37.8), worse among those undergoing concomitant procedures (hazard ratio, 2.14; 95% CI, 1.83-2.50). Late survival after an isolated Bentall was worse than in the age- and sex-matched general population (hazard ratio, 1.49; 95% CI, 1.33-1.68).<\/p>\n<p><strong>Conclusions<\/strong> \u2014 Bentall procedures are associated with excellent short-term outcomes in a complex population with a large number of previous operations, endocarditis, and concomitant procedures. Long-term survival is worse than in age- and sex-matched controls, particularly among younger patients.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective \u2014 The study objective was to evaluate the in-hospital and long-term outcomes of aortic root replacement (Bentall procedure) from a single institution. Methods \u2014 All patients who underwent the Bentall procedure from 1990 to 2014 were included. Aortic valve\u2013sparing root replacement or Ross procedures were excluded. The primary end point was all-cause mortality. The [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[40,62,25],"migration-helper-qa-sample-set":[],"class_list":["post-24412","journal_article","type-journal_article","status-publish","hentry","topic-cardiovascular-disease","topic-health-services-research","topic-surgery"],"acf":{"citation":"Rocha RV, David TE, Chu A, Mazine A, Hassan SMA, Vervoort D, Lee DS, Yau TM, Ouzounian M. Twenty-five-year single-center experience with aortic root replacement with a composite valve graft. JTCVS Open. 2026 Jun 4;32:101886. doi: 10.1016\/j.xjon.2026.101886. PMID: 42604165; PMCID: PMC13477101.","source_url":"https:\/\/doi.org\/10.1016\/j.xjon.2026.101886","ices_scientist":[1290],"site":[6733],"research_program":[6742],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Twenty-five-year single-center experience with aortic root replacement with a composite valve graft<\/title>\n<meta name=\"description\" content=\"Objective \u2014 The study objective was to evaluate the in-hospital and long-term outcomes of aortic root replacement (Bentall procedure) from a single\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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