{"id":24335,"date":"2026-07-22T09:17:12","date_gmt":"2026-07-22T13:17:12","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&p=24335"},"modified":"2026-07-30T09:57:12","modified_gmt":"2026-07-30T13:57:12","slug":"cardiovascular-disease-in-males-with-breast-cancer","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/","title":{"rendered":"Cardiovascular disease in males with breast cancer: a population-based cohort study"},"content":{"rendered":"

Background<\/strong> \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC).<\/p>\n

Objectives<\/strong> \u2014 The objective of the study was to describe CVD risk in males with BC compared to females with BC and cancer-free males.<\/p>\n

Methods<\/strong> \u2014 Population-based cohort study using linked administrative databases. We identified males diagnosed with BC in Ontario, Canada (1998-2021). Male BC patients were age-matched to 3 female BC and 3 male cancer-free controls. The primary outcome was hospitalization or emergency department visits for CVD. Cause-specific mortality was a secondary outcome. Cause-specific hazards regression was used to estimate HRs associated with male BC status.<\/p>\n

Results<\/strong> \u2014 We matched 683 males with BC to 2,049 females with BC and 687 males with BC to 2,061 cancer-free males (median age 68 years [IQR: 59-77 years]). Males with BC had more prevalent pre-existing CVD and risk factors than both comparators. After adjusting for baseline characteristics, male BC was associated with a similar risk of CVD hospitalization\/emergency department visits compared to female BC (HR: 1.03; 95% CI: 0.86-1.25) and cancer-free males (HR: 1.00; 95% CI: 0.84-1.19). Male BC was not associated with higher CVD mortality but was associated with higher cancer mortality relative to both comparator groups.<\/p>\n

Conclusions<\/strong> \u2014 Males with BC have greater baseline cardiovascular risk than females with BC and cancer-free males but no increase in future CVD hazard after adjustment. This highlights the need for prioritizing cancer treatment in males with BC, with appropriate attention to CVD risk management.<\/p>\n","protected":false},"excerpt":{"rendered":"

Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to describe CVD risk in males with BC compared to females with BC and cancer-free males. Methods \u2014 Population-based cohort study using linked administrative databases. We identified males diagnosed with BC […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[38,40],"migration-helper-qa-sample-set":[],"class_list":["post-24335","journal_article","type-journal_article","status-publish","hentry","topic-cancer-and-cancer-screening","topic-cardiovascular-disease"],"acf":{"citation":"Chauhan A, Giannakeas V, Thiruchelvam D, Thavendiranathan P, Amir E, Nadler MB, Savard MF, Abdel-Qadir H. JACC Adv<\/em>. 2026; 5(7): 102937.","source_url":"https:\/\/doi.org\/10.1016\/j.jacadv.2026.102937","ices_scientist":[23247,1379],"site":[6735],"research_program":[6742],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"\nICES | Cardiovascular disease in males with breast cancer: a population-based cohort study<\/title>\n<meta name=\"description\" content=\"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | Cardiovascular disease in males with breast cancer: a population-based cohort study\" \/>\n<meta property=\"og:description\" content=\"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"ICES\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ICESOntario\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-30T13:57:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2024\/11\/ic-es-data-discovery-better-health-logo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/cardiovascular-disease-in-males-with-breast-cancer\\\/\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/cardiovascular-disease-in-males-with-breast-cancer\\\/\",\"name\":\"ICES | Cardiovascular disease in males with breast cancer: a population-based cohort study\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#website\"},\"datePublished\":\"2026-07-22T13:17:12+00:00\",\"dateModified\":\"2026-07-30T13:57:12+00:00\",\"description\":\"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/cardiovascular-disease-in-males-with-breast-cancer\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/cardiovascular-disease-in-males-with-breast-cancer\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/cardiovascular-disease-in-males-with-breast-cancer\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Journal Articles\",\"item\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Cardiovascular disease in males with breast cancer: a population-based cohort study\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\",\"name\":\"ICES\",\"description\":\"POPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#organization\"},\"alternateName\":\"Institute for Clinical Evaluative Sciences\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#organization\",\"name\":\"ICES\",\"alternateName\":\"Institute for Clinical Evaluative Sciences\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/ices-logo.png\",\"contentUrl\":\"https:\\\/\\\/www.ices.on.ca\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/ices-logo.png\",\"width\":\"676\",\"height\":\"618\",\"caption\":\"ICES\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/ICESOntario\\\/\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/ices-research-institute\\\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"ICES | Cardiovascular disease in males with breast cancer: a population-based cohort study","description":"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/","og_locale":"fr_FR","og_type":"article","og_title":"ICES | Cardiovascular disease in males with breast cancer: a population-based cohort study","og_description":"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to","og_url":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/","og_site_name":"ICES","article_publisher":"https:\/\/www.facebook.com\/ICESOntario\/","article_modified_time":"2026-07-30T13:57:12+00:00","og_image":[{"width":1200,"height":675,"url":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2024\/11\/ic-es-data-discovery-better-health-logo.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/","url":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/","name":"ICES | Cardiovascular disease in males with breast cancer: a population-based cohort study","isPartOf":{"@id":"https:\/\/www.ices.on.ca\/fr\/#website"},"datePublished":"2026-07-22T13:17:12+00:00","dateModified":"2026-07-30T13:57:12+00:00","description":"Background \u2014 There are scarce data on cardiovascular disease (CVD) risk in male breast cancer (BC). Objectives \u2014 The objective of the study was to","breadcrumb":{"@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/cardiovascular-disease-in-males-with-breast-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.ices.on.ca\/fr\/"},{"@type":"ListItem","position":2,"name":"Journal Articles","item":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/"},{"@type":"ListItem","position":3,"name":"Cardiovascular disease in males with breast cancer: a population-based cohort study"}]},{"@type":"WebSite","@id":"https:\/\/www.ices.on.ca\/fr\/#website","url":"https:\/\/www.ices.on.ca\/fr\/","name":"ICES","description":"POPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE","publisher":{"@id":"https:\/\/www.ices.on.ca\/fr\/#organization"},"alternateName":"Institute for Clinical Evaluative Sciences","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ices.on.ca\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.ices.on.ca\/fr\/#organization","name":"ICES","alternateName":"Institute for Clinical Evaluative Sciences","url":"https:\/\/www.ices.on.ca\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.ices.on.ca\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/04\/ices-logo.png","contentUrl":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/04\/ices-logo.png","width":"676","height":"618","caption":"ICES"},"image":{"@id":"https:\/\/www.ices.on.ca\/fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ICESOntario\/","https:\/\/www.linkedin.com\/company\/ices-research-institute\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/journal_article\/24335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/journal_article"}],"about":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/types\/journal_article"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/research_program\/6742"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/site\/6735"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/ices_scientist\/1379"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/ices_scientist\/23247"}],"wp:attachment":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/media?parent=24335"}],"wp:term":[{"taxonomy":"migration-helper-automated","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-helper-automated?post=24335"},{"taxonomy":"migration-manual","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-manual?post=24335"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/topic?post=24335"},{"taxonomy":"migration-helper-qa-sample-set","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-helper-qa-sample-set?post=24335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}