{"id":24218,"date":"2026-06-10T16:05:02","date_gmt":"2026-06-10T20:05:02","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&p=24218"},"modified":"2026-06-26T16:09:05","modified_gmt":"2026-06-26T20:09:05","slug":"impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/","title":{"rendered":"Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study"},"content":{"rendered":"

Objectives<\/strong> \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\u00ab\u00a0ON-Marg\u00a0\u00bb), and overall survival (OS) in epithelial ovarian cancer (EOC).<\/p>\n

Methods<\/strong> \u2014 This was a population-based retrospective cohort study using linked administrative data in Ontario, Canada, including adults \u2265 18 years diagnosed with stage II-IV EOC (2010-2022). ON-Marg dimensions included Material Resources (economic disadvantage), Households and Dwellings (housing type\/density), Age and Labour Force (workforce participation), and Racialized and Newcomer Populations (recent immigrants\/visible minorities), and were categorized into quintiles (Q1 least marginalized, Q5 most marginalized). The primary outcome was OS. Multivariable Cox models estimated adjusted hazard ratios (aHR) for each ON-Marg dimension. Wald \u03c72 statistics identified the dimension most strongly associated with OS.<\/p>\n

Results<\/strong> \u2014 Material Resources was most strongly associated with OS. Compared with Q1 (least marginalized), higher mortality was observed in Q3 (aHR 1.10; 95%CI 1.02-1.19), Q4 (aHR 1.13, 95%CI 1.05-1.22), and Q5 (aHR 1.25, 95%CI 1.15-1.35). Greater marginalization in the Racialized and Newcomer Populations dimension was associated with improved OS (Q5 aHR 0.87, 95%CI 0.80-0.94). The association between Material Resources and OS persisted in patients undergoing cytoreductive surgery with chemotherapy, but not among those receiving chemotherapy alone or no treatment.<\/p>\n

Conclusions<\/strong> \u2014 Material Resources is an independent predictor of survival in EOC within a universal, publicly funded healthcare system, with greatest impact among patients undergoing multimodal oncologic care. Residence in highly racialized or newcomer communities was associated with improved survival. Material marginalization is highlighted as a key driver of inequity, supporting targeted system-level interventions to address financial and logistical barriers to care.<\/p>\n","protected":false},"excerpt":{"rendered":"

Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\u00ab\u00a0ON-Marg\u00a0\u00bb), and overall survival (OS) in epithelial ovarian cancer (EOC). Methods \u2014 This was a population-based retrospective cohort study using linked administrative data in Ontario, Canada, including adults \u2265 18 years diagnosed with stage II-IV EOC (2010-2022). ON-Marg dimensions […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[38,20],"migration-helper-qa-sample-set":[],"class_list":["post-24218","journal_article","type-journal_article","status-publish","hentry","topic-cancer-and-cancer-screening","topic-health-and-health-care-inequality"],"acf":{"citation":"Lim JW, Gien LT, Ante Z, Liu N, Philp L, Grewal K, Bouchard-Fortier G. Cancers (Basel)<\/em>. 2026; 18(12): 1892.","source_url":"https:\/\/doi.org\/10.3390\/cancers18121892","ices_scientist":[1247,1237,20864],"site":[6733],"research_program":[6741],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"\nICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study<\/title>\n<meta name=\"description\" content=\"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index ("ON-Marg"), and overall\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study\" \/>\n<meta property=\"og:description\" content=\"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index ("ON-Marg"), and overall\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"ICES\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ICESOntario\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-26T20:09:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2024\/11\/ic-es-data-discovery-better-health-logo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\\\/\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\\\/\",\"name\":\"ICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#website\"},\"datePublished\":\"2026-06-10T20:05:02+00:00\",\"dateModified\":\"2026-06-26T20:09:05+00:00\",\"description\":\"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\\\"ON-Marg\\\"), and overall\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Journal Articles\",\"item\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/publications\\\/journal-articles\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\",\"name\":\"ICES\",\"description\":\"POPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#organization\"},\"alternateName\":\"Institute for Clinical Evaluative Sciences\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#organization\",\"name\":\"ICES\",\"alternateName\":\"Institute for Clinical Evaluative Sciences\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.ices.on.ca\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/ices-logo.png\",\"contentUrl\":\"https:\\\/\\\/www.ices.on.ca\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/ices-logo.png\",\"width\":\"676\",\"height\":\"618\",\"caption\":\"ICES\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ices.on.ca\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/ICESOntario\\\/\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/ices-research-institute\\\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"ICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study","description":"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\"ON-Marg\"), and overall","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/","og_locale":"fr_FR","og_type":"article","og_title":"ICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study","og_description":"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\"ON-Marg\"), and overall","og_url":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/","og_site_name":"ICES","article_publisher":"https:\/\/www.facebook.com\/ICESOntario\/","article_modified_time":"2026-06-26T20:09:05+00:00","og_image":[{"width":1200,"height":675,"url":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2024\/11\/ic-es-data-discovery-better-health-logo.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/","url":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/","name":"ICES | Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study","isPartOf":{"@id":"https:\/\/www.ices.on.ca\/fr\/#website"},"datePublished":"2026-06-10T20:05:02+00:00","dateModified":"2026-06-26T20:09:05+00:00","description":"Objectives \u2014 We aimed to examine associations between social marginalization, defined by the Ontario Marginalization Index (\"ON-Marg\"), and overall","breadcrumb":{"@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/impact-of-marginalization-dimensions-on-survival-disparities-in-epithelial-ovarian-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.ices.on.ca\/fr\/"},{"@type":"ListItem","position":2,"name":"Journal Articles","item":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/"},{"@type":"ListItem","position":3,"name":"Impact of marginalization dimensions on survival disparities in epithelial ovarian cancer: an Ontario population-based study"}]},{"@type":"WebSite","@id":"https:\/\/www.ices.on.ca\/fr\/#website","url":"https:\/\/www.ices.on.ca\/fr\/","name":"ICES","description":"POPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE","publisher":{"@id":"https:\/\/www.ices.on.ca\/fr\/#organization"},"alternateName":"Institute for Clinical Evaluative Sciences","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ices.on.ca\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.ices.on.ca\/fr\/#organization","name":"ICES","alternateName":"Institute for Clinical Evaluative Sciences","url":"https:\/\/www.ices.on.ca\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.ices.on.ca\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/04\/ices-logo.png","contentUrl":"https:\/\/www.ices.on.ca\/wp-content\/uploads\/2023\/04\/ices-logo.png","width":"676","height":"618","caption":"ICES"},"image":{"@id":"https:\/\/www.ices.on.ca\/fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ICESOntario\/","https:\/\/www.linkedin.com\/company\/ices-research-institute\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/journal_article\/24218","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/journal_article"}],"about":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/types\/journal_article"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/research_program\/6741"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/site\/6733"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/ices_scientist\/20864"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/ices_scientist\/1237"},{"embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/ices_scientist\/1247"}],"wp:attachment":[{"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/media?parent=24218"}],"wp:term":[{"taxonomy":"migration-helper-automated","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-helper-automated?post=24218"},{"taxonomy":"migration-manual","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-manual?post=24218"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/topic?post=24218"},{"taxonomy":"migration-helper-qa-sample-set","embeddable":true,"href":"https:\/\/www.ices.on.ca\/fr\/wp-json\/wp\/v2\/migration-helper-qa-sample-set?post=24218"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}