{"id":2409,"date":"2021-01-20T00:00:00","date_gmt":"2021-01-20T05:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/immigration-status-ethnicity-and-long-term-outcomes-following-ischemic-stroke\/"},"modified":"2023-06-14T19:59:45","modified_gmt":"2023-06-14T23:59:45","slug":"immigration-status-ethnicity-and-long-term-outcomes-following-ischemic-stroke","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/immigration-status-ethnicity-and-long-term-outcomes-following-ischemic-stroke\/","title":{"rendered":"Immigration status, ethnicity, and long-term outcomes following ischemic stroke"},"content":{"rendered":"<p><strong>Objective <\/strong>&#x2014; To assess the association between immigration status and ethnicity and the outcomes of mortality and vascular event recurrence following ischemic stroke in Ontario, Canada.<\/p>\n<p><strong>Methods <\/strong>&#x2014; We conducted a retrospective cohort study using linked administrative and clinical registry-based data from 2002 to 2018 and compared hazards of all-cause mortality and vascular event recurrence in immigrants and long-term residents using inverse probability of treatment weighting accounting for age, sex, income and comorbidities. We stratified analyses by age (&#x2264; 75 and &gt; 75 years) and used interaction terms to evaluate if the association between immigration status and outcomes varied with age or ethnicity.<\/p>\n<p><strong>Results <\/strong>&#x2014; We followed 31,918 adult patients, of whom 2740 (8.6%) were immigrants, for a median follow-up of 5 years. Immigrants had a lower mortality than long-term residents (46.1% vs. 64.5%) which was attenuated after adjustment (hazard ratio 0.94; 95% confidence interval 0.88-1.00), but persisted in those aged under 75 years (HR 0.82; 0.74-0.91). Compared to their respective ethnic long-term resident counterparts, the adjusted hazard of death was higher in South Asian immigrants, similar in Chinese immigrants, and lower in other immigrants (P value for interaction = 0.003). The adjusted hazard of vascular event recurrence (HR 1.01; 0.92-1.11) was similar in immigrants and long-term residents, and this observation persisted across all age and ethnic groups.<\/p>\n<p><strong>Conclusions <\/strong>&#x2014; Long-term mortality following ischemic stroke is lower in immigrants and long-term residents, but is similar after adjustment of baseline characteristics, and it is modified by age at the time of stroke and by ethnicity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective &#x2014; To assess the association between immigration status and ethnicity and the outcomes of mortality and vascular event recurrence following ischemic stroke in Ontario, Canada. Methods &#x2014; We conducted a retrospective cohort study using linked administrative and clinical registry-based data from 2002 to 2018 and compared hazards of all-cause mortality and vascular event recurrence [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[],"migration-helper-qa-sample-set":[],"class_list":["post-2409","journal_article","type-journal_article","status-publish","hentry"],"acf":{"citation":"Vyas MV, Austin PC, Fang J, Laupacis A, Silver FL, Kapral MK. <em>Neurology<\/em>. 2021; 96(8):e1145-55. Epub 2021 Jan 20.","source_url":"https:\/\/doi.org\/10.1212\/WNL.0000000000011451","ices_scientist":[1385,1293,1375,1150,1118],"site":[6733],"research_program":[6742],"news_release":[],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"21F96747-5330-43CB-8281-BC869C2D42BA","sitecore_item_name":"Immigration-status-ethnicity-and-long-term-outcomes-following-ischemic-stroke","sitecore_field_values":"{\n  \"Title\": \"Immigration status, ethnicity, and long-term outcomes following ischemic stroke\",\n  \"Short title\": \"Immigration status, ethnicity, and\",\n  \"Summary\": \"This study aimed to assess the association between immigration status and ethnicity and the outcomes of mortality and vascular event recurrence following ischemic stroke in Ontario, Canada.\",\n  \"Citation\": \"<p>Vyas MV, Austin PC, Fang J, Laupacis A, Silver FL, Kapral MK. <em>Neurology<\/em>. 2021; 96(8):e1145-55. Epub 2021 Jan 20. DOI: <a href=\"https:\/\/doi.org\/10.1212\/WNL.0000000000011451\" title=\"opens external link\">nhttps:\/\/doi.org\/10.1212\/WNL.0000000000011451<\/a><\/p>\",\n  \"Abstract\": \"<p><strong>Objective <\/strong>&mdash; To assess the association between immigration status and ethnicity and the outcomes of mortality and vascular event recurrence following ischemic stroke in Ontario, Canada.<\/p>n<p><strong>Methods <\/strong>&mdash; We conducted a retrospective cohort study using linked administrative and clinical registry-based data from 2002 to 2018 and compared hazards of all-cause mortality and vascular event recurrence in immigrants and long-term residents using inverse probability of treatment weighting accounting for age, sex, income and comorbidities. We stratified analyses by age (&le; 75 and &gt; 75 years) and used interaction terms to evaluate if the association between immigration status and outcomes varied with age or ethnicity.<\/p>n<p><strong>Results <\/strong>&mdash; We followed 31,918 adult patients, of whom 2740 (8.6%) were immigrants, for a median follow-up of 5 years. Immigrants had a lower mortality than long-term residents (46.1% vs. 64.5%) which was attenuated after adjustment (hazard ratio 0.94; 95% confidence interval 0.88-1.00), but persisted in those aged under 75 years (HR 0.82; 0.74-0.91). Compared to their respective ethnic long-term resident counterparts, the adjusted hazard of death was higher in South Asian immigrants, similar in Chinese immigrants, and lower in other immigrants (P value for interaction = 0.003). The adjusted hazard of vascular event recurrence (HR 1.01; 0.92-1.11) was similar in immigrants and long-term residents, and this observation persisted across all age and ethnic groups.<\/p>n<p><strong>Conclusions <\/strong>&mdash; Long-term mortality following ischemic stroke is lower in immigrants and long-term residents, but is similar after adjustment of baseline characteristics, and it is modified by age at the time of stroke and by ethnicity.<\/p>\",\n  \"Research Programs\": \"{BEC72DE0-BA8C-42B8-ACE5-EE29FFB2CB3B}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{7D498E8B-5801-4F9E-AC41-11ED50F3C34E}|{83920C20-06BE-4C6B-9FA7-06B69A509A24}|{BA7F184D-0B54-4C38-827F-77223D5A2AC7}|{85A20A85-A5DB-4EC9-A9C2-DDBB2DEDBF72}|{A427077E-906B-463B-8DC1-8DB109670483}\",\n  \"Posted Date\": \"20210120T000000\",\n  \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2021\/January\/Immigration-status-ethnicity-and-long-term-outcomes-following-ischemic-stroke"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Immigration status, ethnicity, and long-term outcomes following ischemic stroke<\/title>\n<meta name=\"description\" content=\"Objective &#x2014; 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