{"id":22268,"date":"2025-03-31T16:04:43","date_gmt":"2025-03-31T20:04:43","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=22268"},"modified":"2025-08-18T16:09:24","modified_gmt":"2025-08-18T20:09:24","slug":"clinical-characteristics-of-inpatients-with-schizophrenia-spectrum-disorder-treated-with-electroconvulsive-therapy","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/clinical-characteristics-of-inpatients-with-schizophrenia-spectrum-disorder-treated-with-electroconvulsive-therapy\/","title":{"rendered":"Clinical characteristics of inpatients with schizophrenia spectrum disorder treated with electroconvulsive therapy: a population-level cross-sectional study"},"content":{"rendered":"<p><strong>Objective<\/strong> \u2014 Electroconvulsive therapy (ECT) is an evidence-based treatment for schizophrenia when anti-psychotic medications do not sufficiently control symptoms of psychosis or rapid response is required. Little is known about how it is used in routine clinical practice. The aim of this study was to identify the association of demographic and clinical characteristics with administration of ECT for schizophrenia spectrum disorders (SSD).<\/p>\n<p><strong>Methods<\/strong> \u2014 Among psychiatric inpatients with a diagnosis of SSD in Ontario, Canada (2006\u20132023), patient-level socio-demographic and clinical characteristics were described in those who did and did not receive ECT. We used multi-variable logistic regression to assess the association between patient-level characteristics and administration of ECT during index hospitalization.<\/p>\n<p><strong>Results<\/strong> \u2014 From 164,632 admissions, 2,168 (1.3%) involved exposure to \u22651 inpatient ECT procedure. Compared to those not receiving ECT, those receiving ECT were older, had higher rates of pre-admission medication use, medical and psychiatric comorbidities, outpatient mental health service use, but lower rates of substance use disorders. In the multi-variable logistic regression model, patient-level characteristics most strongly associated with receiving inpatient ECT were the presence of catatonia (odds ratio [OR]: 5.83; 95% confidence interval [95% CI]: 4.01\u20138.46), comorbid depression (OR: 2.49; 95% CI: 2.07\u20132.98), obsessive-compulsive disorder (OR: 2.16; 95% CI: 1.55\u20133.00), while characteristics most strongly associated with not receiving inpatient ECT were myocardial infarction (OR: 0.44; 95% CI: 0.20\u20130.95) and family conflict towards patient (OR: 0.47; 95% CI: 0.31\u20130.71). Neither severity of psychotic symptoms, non-command auditory hallucinations nor delusions were associated with administration of ECT.<\/p>\n<p><strong>Conclusions<\/strong> \u2014 While characteristics associated with the use of ECT are generally consistent with the indications for ECT (e.g., catatonia, mood disorders), ECT is rarely used amongst individuals with SSD. Severity of psychotic symptoms was not associated with the use of inpatient ECT suggesting an opportunity to increase the use of ECT in this population.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective \u2014 Electroconvulsive therapy (ECT) is an evidence-based treatment for schizophrenia when anti-psychotic medications do not sufficiently control symptoms of psychosis or rapid response is required. Little is known about how it is used in routine clinical practice. The aim of this study was to identify the association of demographic and clinical characteristics with administration [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[34],"migration-helper-qa-sample-set":[],"class_list":["post-22268","journal_article","type-journal_article","status-publish","hentry","topic-mental-health-and-addictions"],"acf":{"citation":"Kaster TS, Babujee A, Sharpe I, Rhee TG, Gomes T, Kurdyak P, Foussias G, Wijeysundera D, Blumberger DM, Vigod SN. <em>Can J Psychiatry<\/em>. 2025; 70(3):194-208. Epub 2024 Nov 11.","source_url":"https:\/\/doi.org\/10.1177\/07067437241290181","ices_scientist":[17098,1252,1152,1132,1116],"site":[6733],"research_program":[6744],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Clinical characteristics of inpatients with schizophrenia spectrum disorder treated with electroconvulsive therapy: a population-level cross-sectional study<\/title>\n<meta name=\"description\" content=\"Objective \u2014 Electroconvulsive therapy (ECT) is an evidence-based treatment for schizophrenia when anti-psychotic medications do not sufficiently control\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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