{"id":22049,"date":"2025-07-01T11:00:01","date_gmt":"2025-07-01T15:00:01","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&p=22049"},"modified":"2025-07-03T11:32:33","modified_gmt":"2025-07-03T15:32:33","slug":"covid-19-vaccine-uptake-in-a-retrospective-population-based-cohort-of-people-living-with-and-without-hiv-in-ontario-canada","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/covid-19-vaccine-uptake-in-a-retrospective-population-based-cohort-of-people-living-with-and-without-hiv-in-ontario-canada\/","title":{"rendered":"COVID-19 vaccine uptake in a retrospective population-based cohort of people living with and without HIV in Ontario, Canada"},"content":{"rendered":"

Introduction<\/strong> \u2014 COVID-19 vaccination significantly reduces COVID-19-related hospitalization and mortality and is important for those who may be at increased risk of SARS-CoV-2 infection, including people living with HIV. Using a population-based approach, we examined COVID-19 vaccine uptake among people living with and without HIV in Ontario, Canada.<\/p>\n

Methods<\/strong> \u2014 A retrospective population-based matched cohort study was conducted using provincial clinical and health administrative data from December 14, 2020 to August 31, 2022. Community-dwelling adults living with HIV aged \u226519 years were matched one-to-one with a person without a diagnosis of HIV based on age, sex, geography, and immigration status. To identify predictors of vaccine uptake, modified Poisson regression with robust standard errors accounting for geographical clustering was used. To estimate vaccine uptake comparing the HIV and non-HIV cohorts, conditional Poisson regression with robust error variance was used to estimate crude and adjusted risk ratios with 95 % confidence intervals (CI).<\/p>\n

Results<\/strong> \u2014 Among 20,903 people living with HIV, most (85.4%) had received \u22652 COVID-19 vaccine doses, with 64.7% receiving a third dose and 24.3% receiving a fourth dose. Disparities in uptake of \u22653 doses by sex were observed (males vs females: 68.5% vs 50.9%). Predictors of receiving \u22653 doses among people living with HIV included older age, male sex, and receipt of a recent influenza vaccine. Men living with HIV were more likely to receive \u22653 doses compared with men living without HIV, whereas women living with HIV were less likely than women living without HIV to receive \u22653 doses.<\/p>\n

Conclusions<\/strong> \u2014 Uptake of the first two doses of COVID-19 vaccine was high among people living with HIV in Ontario, Canada, however, disparities in uptake of \u22653 doses remain, especially by sex. Continued monitoring of COVID-19 vaccine uptake is crucial to informing immunization programs, policies and guidelines for people living with HIV in Canada.<\/p>\n","protected":false},"excerpt":{"rendered":"

Introduction \u2014 COVID-19 vaccination significantly reduces COVID-19-related hospitalization and mortality and is important for those who may be at increased risk of SARS-CoV-2 infection, including people living with HIV. Using a population-based approach, we examined COVID-19 vaccine uptake among people living with and without HIV in Ontario, Canada. Methods \u2014 A retrospective population-based matched cohort […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[39,56,35],"migration-helper-qa-sample-set":[],"class_list":["post-22049","journal_article","type-journal_article","status-publish","hentry","topic-infectious-diseases","topic-pharmacoepidemiology-and-drug-safety","topic-public-health"],"acf":{"citation":"Freitas C, Cooper CL, Kroch AE, Moineddin R, Arbess G, Benoit AC, Buchan SA, Chambers C, Habanyama M, Kendall CE, Kwong JC, Mbuagbaw L, McCullagh J, Moqueet N, Nambiar D, Rueda S, Tran V, Walmsley S, Burchell AN; CHESS Study Team. Vaccine<\/em>. 2025; 61:127422. Epub 2025 Jul 1.","source_url":"https:\/\/doi.org\/10.1016\/j.vaccine.2025.127422","ices_scientist":[1327,1161,1157,1149,1171,22730],"site":[6733],"research_program":[6745],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"\nICES | COVID-19 vaccine uptake in a retrospective population-based cohort of people living with and without HIV in Ontario, Canada<\/title>\n<meta name=\"description\" content=\"Introduction \u2014 COVID-19 vaccination significantly reduces COVID-19-related hospitalization and mortality and is important for those who may be at\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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