{"id":20621,"date":"2024-10-21T16:57:32","date_gmt":"2024-10-21T20:57:32","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=20621"},"modified":"2024-11-01T17:04:14","modified_gmt":"2024-11-01T21:04:14","slug":"high-cost-users-after-sepsis","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/high-cost-users-after-sepsis\/","title":{"rendered":"High-cost users after sepsis: a population-based observational cohort study"},"content":{"rendered":"<p><strong>Background <\/strong>\u2014\u00a0High-cost users (HCU) represent important targets for health policy interventions. Sepsis is a life-threatening syndrome that is associated with high morbidity, mortality, and economic costs to the healthcare system. We sought to estimate the effect of sepsis on being a subsequent HCU.<\/p>\n<p><strong>Methods <\/strong>\u2014\u00a0Using linked health-administrative databases, we conducted a population-based, propensity score-weighted cohort study of adults who survived a hospitalization in Ontario, Canada between January 2016 and December 2017. Sepsis was identified using a validated algorithm. The primary outcome was being a persistent HCU after hospital discharge (in the top 5% or 1% of total health care spending for 90 consecutive days), and the proportion of follow-up time since discharge as a HCU.<\/p>\n<p><strong>Results <\/strong>\u2014\u00a0We identified 927,057 hospitalized individuals, of whom 79,065 had sepsis. Individuals who had sepsis were more likely to be a top 5% HCU for 90 consecutive days at any time after discharge compared to those without sepsis (OR 2.24; 95% confidence interval [CI] 2.04\u20132.46) and spent on average 42.3% of their follow up time as a top 5% HCU compared to 28.9% of time among those without sepsis (RR 1.46; 95% CI 1.45\u20131.48). Individuals with sepsis were more likely to be a top 1% HCU for 90 consecutive days compared to those without sepsis (10% versus 5.1%, OR 2.05 [95% CI 1.99\u20132.11]), and spent more time as a top 1% HCU (18.5% of time versus 10.8% of time, RR 1.68 [95% CI 1.65\u20131.70]).<\/p>\n<p><strong>Conclusions<\/strong> \u2014\u00a0The sequelae of sepsis result in higher healthcare costs with important economic implications. After discharge, individuals who experienced sepsis are more likely to be a HCU and spend more time as a HCU compared to individuals who did not experience sepsis during hospitalization.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background \u2014\u00a0High-cost users (HCU) represent important targets for health policy interventions. Sepsis is a life-threatening syndrome that is associated with high morbidity, mortality, and economic costs to the healthcare system. We sought to estimate the effect of sepsis on being a subsequent HCU. Methods \u2014\u00a0Using linked health-administrative databases, we conducted a population-based, propensity score-weighted cohort [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[61],"migration-helper-qa-sample-set":[],"class_list":["post-20621","journal_article","type-journal_article","status-publish","hentry","topic-health-economics"],"acf":{"citation":"Barrett KA, Sheikh F, Chechulina V, Chung H, Dodek P, Rosella L, Thavorn K, Scales DC; Sepsis Canada. <em>Crit Care<\/em>. 2024; 28(1):338.","source_url":"https:\/\/doi.org\/10.1186\/s13054-024-05108-6","ices_scientist":[1339,1105,1364],"site":[6733],"research_program":[6747],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | High-cost users after sepsis: a population-based observational cohort study<\/title>\n<meta name=\"description\" content=\"Background \u2014\u00a0High-cost users (HCU) represent important targets for health policy interventions. Sepsis is a life-threatening syndrome that is associated\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/high-cost-users-after-sepsis\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | High-cost users after sepsis: a population-based observational cohort study\" \/>\n<meta property=\"og:description\" content=\"Background \u2014\u00a0High-cost users (HCU) represent important targets for health policy interventions. 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