{"id":19916,"date":"2024-07-01T15:35:40","date_gmt":"2024-07-01T19:35:40","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=19916"},"modified":"2024-07-25T15:40:19","modified_gmt":"2024-07-25T19:40:19","slug":"prescription-medication-use-in-pregnancy-in-people-with-disabilities","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/prescription-medication-use-in-pregnancy-in-people-with-disabilities\/","title":{"rendered":"Prescription medication use in pregnancy in people with disabilities: a population-based cohort study"},"content":{"rendered":"<p><strong>Background<\/strong> \u2014 Individuals with disabilities may require specific medications in pregnancy. The prevalence and patterns of medication use, overall and for medications with known teratogenic risks, are largely unknown.<\/p>\n<p><strong>Methods<\/strong> \u2014 This population-based cohort study in Ontario, Canada, 2004-2021, comprised all recognized pregnancies among individuals eligible for public drug plan coverage. Included were those with a physical (n = 44,136), sensory (n = 13,633), intellectual or developmental (n = 2,446) disability, or multiple disabilities (n = 5,064), compared with those without a disability (n = 299,944). Prescription medication use in pregnancy, overall and by type, was described. Modified Poisson regression generated relative risks (aRR) for the use of medications with known teratogenic risks and use of \u22652 and \u22655 medications concurrently in pregnancy, comparing those with versus without a disability, adjusting for sociodemographic and clinical factors.<\/p>\n<p><strong>Results<\/strong> \u2014 Medication use in pregnancy was more common in people with intellectual or developmental (82.1%), multiple (80.4%), physical (73.9%), and sensory (71.9%) disabilities, than in those with no known disability (67.4%). Compared with those without a disability (5.7%), teratogenic medication use in pregnancy was especially higher in people with multiple disabilities (14.2%; aRR 2.03, 95% confidence interval [CI]: 1.88-2.20). Furthermore, compared with people without a disability (3.2%), the use of \u22655 medications concurrently was more common in those with multiple disabilities (13.4%; aRR 2.21, 95% CI: 2.02-2.41) and an intellectual or developmental disability (9.3%; aRR 2.13, 95% CI: 1.86-2.45).<\/p>\n<p><strong>Interpretation<\/strong> \u2014 Among people with disabilities, medication use in pregnancy is prevalent, especially for potentially teratogenic medications and polypharmacy, highlighting the need for preconception counseling\/monitoring to reduce medication-related harm in pregnancy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background \u2014 Individuals with disabilities may require specific medications in pregnancy. The prevalence and patterns of medication use, overall and for medications with known teratogenic risks, are largely unknown. Methods \u2014 This population-based cohort study in Ontario, Canada, 2004-2021, comprised all recognized pregnancies among individuals eligible for public drug plan coverage. Included were those with [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[19,26,56],"migration-helper-qa-sample-set":[],"class_list":["post-19916","journal_article","type-journal_article","status-publish","hentry","topic-marginalized-populations","topic-maternity-and-neonatal-care","topic-pharmacoepidemiology-and-drug-safety"],"acf":{"citation":"Camden A, Grandi SM, Lunsky Y, Ray JG, Sharpe I, Lu H, Guttmann A, Tailor L, Vigod S, De Vera MA, Brown HK. <em>J Womens Health (Larchmt)<\/em>. 2024; Jul 1 [Epub ahead of print].","source_url":"https:\/\/doi.org\/10.1089\/jwh.2023.1138","ices_scientist":[1236,1296,1338,1238,1116,1164],"site":[6733],"research_program":[6744],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Prescription medication use in pregnancy in people with disabilities: a population-based cohort study<\/title>\n<meta name=\"description\" content=\"Background \u2014 Individuals with disabilities may require specific medications in pregnancy. The prevalence and patterns of medication use, overall and for\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/prescription-medication-use-in-pregnancy-in-people-with-disabilities\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | Prescription medication use in pregnancy in people with disabilities: a population-based cohort study\" \/>\n<meta property=\"og:description\" content=\"Background \u2014 Individuals with disabilities may require specific medications in pregnancy. 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