{"id":17380,"date":"2024-02-08T13:03:36","date_gmt":"2024-02-08T18:03:36","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=17380"},"modified":"2024-02-09T16:05:12","modified_gmt":"2024-02-09T21:05:12","slug":"sex-based-disparities-in-acute-myocardial-infarction-treatment-patterns-and-outcomes-in-older-adults-hospitalized-across-6-high-income-countries-an-analysis-from-the-international-health-systems-rese","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/sex-based-disparities-in-acute-myocardial-infarction-treatment-patterns-and-outcomes-in-older-adults-hospitalized-across-6-high-income-countries-an-analysis-from-the-international-health-systems-rese\/","title":{"rendered":"Sex-based disparities in acute myocardial infarction treatment patterns and outcomes in older adults hospitalized across 6 high-income countries: an analysis from the international health systems research collaborative"},"content":{"rendered":"<p><strong>Background<\/strong> \u2014 Sex differences in acute myocardial infarction treatment and outcomes are well documented, but it is unclear whether differences are consistent across countries. The objective of this study was to investigate the epidemiology, use of interventional procedures, and outcomes for older females and males hospitalized with ST-segment\u2013elevation myocardial infarction (STEMI) and non\u2013ST-segment\u2013elevation myocardial infarction (NSTEMI) in 6 diverse countries.<\/p>\n<p><strong>Methods<\/strong> \u2014 We conducted a serial cross-sectional cohort study of 1 508 205 adults aged \u226566 years hospitalized with STEMI and NSTEMI between 2011 and 2018 in the United States, Canada, England, the Netherlands, Taiwan, and Israel using administrative data. We compared females and males within each country with respect to age-standardized hospitalization rates, rates of cardiac catheterization, percutaneous coronary intervention, and coronary artery bypass graft surgery within 90 days of hospitalization, and 30-day age- and comorbidity-adjusted mortality.<\/p>\n<p><strong>Results<\/strong> \u2014 Hospitalization rates for STEMI and NSTEMI decreased between 2011 and 2018 in all countries, although the hospitalization rate ratio (rate in males\/rate in females) increased in virtually all countries (eg, US STEMI ratio, 1.58:1 in 2011 and 1.73:1 in 2018; Israel NSTEMI ratio, 1.71:1 in 2011 and 2.11:1 in 2018). Rates of cardiac catheterization, percutaneous coronary intervention, and coronary artery bypass graft surgery were lower for females than males for STEMI in all countries and years (eg, US cardiac catheterization in 2018, 88.6% for females versus 91.5% for males; Israel percutaneous coronary intervention in 2018, 76.7% for females versus 84.8% for males) with similar findings for NSTEMI. Adjusted mortality for STEMI in 2018 was higher for females than males in 5 countries (the United States, Canada, the Netherlands, Israel, and Taiwan) but lower for females than males in 5 countries for NSTEMI.<\/p>\n<p><strong>Conclusions<\/strong> \u2014 We observed a larger decline in acute myocardial infarction hospitalizations for females than males between 2011 and 2018. Females were less likely to receive cardiac interventions and had higher mortality after STEMI. Sex disparities seem to transcend borders, raising questions about the underlying causes and remedies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background \u2014 Sex differences in acute myocardial infarction treatment and outcomes are well documented, but it is unclear whether differences are consistent across countries. The objective of this study was to investigate the epidemiology, use of interventional procedures, and outcomes for older females and males hospitalized with ST-segment\u2013elevation myocardial infarction (STEMI) and non\u2013ST-segment\u2013elevation myocardial infarction [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[40,20,25,21],"migration-helper-qa-sample-set":[],"class_list":["post-17380","journal_article","type-journal_article","status-publish","hentry","topic-cardiovascular-disease","topic-health-and-health-care-inequality","topic-surgery","topic-women-or-gender-based-research"],"acf":{"citation":"Lu H, Hatfield LA, Al-Azazi S, Bakx P, Banerjee A, Burrack N, Chen YC, Fu C, Gordon M, Heine R, Huang N, Ko DT, Lix LM, Novack V, Pasea L, Qiu F, Stukel TA, Uyl-de Groot C, Weinreb G, Landon BE, Cram P. <em>Circ Cardiovasc Qual Outcomes<\/em>. 2024; Feb 8 [Epub ahead of print].","source_url":"https:\/\/doi.org\/10.1161\/circoutcomes.123.010144","ices_scientist":[1187,1372,1146],"site":[6733],"research_program":[6742],"news_release":[17381],"journal_article":"","atlas":"","research_report":"","infographic":[17378],"video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Sex-based disparities in acute myocardial infarction treatment patterns and outcomes in older adults hospitalized across 6 high-income countries: an analysis from the international health systems research collaborative<\/title>\n<meta name=\"description\" content=\"Background \u2014 Sex differences in acute myocardial infarction treatment and outcomes are well documented, but it is unclear whether differences are\" \/>\n<meta name=\"robots\" content=\"index, follow, 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