{"id":17354,"date":"2024-02-05T18:30:00","date_gmt":"2024-02-05T23:30:00","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=17354"},"modified":"2024-03-25T14:33:17","modified_gmt":"2024-03-25T18:33:17","slug":"development-of-an-anxiety-disorder-following-an-emergencydepartment-visit-due-to-cannabis-use","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/development-of-an-anxiety-disorder-following-an-emergencydepartment-visit-due-to-cannabis-use\/","title":{"rendered":"Development of an anxiety disorder following an emergency department visit due to cannabis use: a population-based cohort study"},"content":{"rendered":"<p><strong>Background<\/strong> \u2014 There is ongoing uncertainty about whether cannabis use increases the risk of developing an anxiety disorder. In this study we estimated the risk of having an incident healthcare visit for an anxiety disorder following an emergency department (ED) visit for cannabis use and explored factors associated with increased risk.<\/p>\n<p><strong>Methods<\/strong> \u2014 We used health administrative data to perform a population-based cohort study of all individuals aged 10\u2013105 years with no previous healthcare visits for anxiety disorders in Ontario, Canada, between January 2008 and March 2019. We compared the risk of having an incident healthcare visit for an anxiety disorder in the ED or hospital (primary analysis) or additionally in an outpatient setting (secondary analysis) for individuals with an incident ED visit for cannabis to members of the general population using cumulative incidence functions and cause-specific hazard models adjusted for relevant confounders.<\/p>\n<p><strong>Findings<\/strong> \u2014 Our study included 12,099,144 individuals aged 10\u2013105 without prior care for an anxiety disorder in the ED or hospital, of which 34,822 (0.29%) had an incident ED visit due to cannabis. Within 3-years of an incident ED visit due to cannabis, 12.3% (n = 4294) of individuals had an incident ED visit or hospitalization for an anxiety disorder\u2014a 3.7-fold (adjusted Hazard Ratio [aHR] 3.69 95% CI 3.57\u20133.82) increased risk relative to the general population (1.2%). In secondary analysis, further excluding individuals with prior outpatient care for anxiety disorders, 23.6% of individuals with an ED visit due to cannabis had an incident outpatient visit, ED visit, or hospitalization for an anxiety disorder within 3-years compared to 5.6% of individuals in the general population (aHR 3.88 95% CI 3.77\u20132.99). The risk of having an incident healthcare visit for an anxiety disorder was higher in individuals with ED visits for cannabis use compared to the general population across all age and sex strata. However, younger males with ED visits for cannabis use (aHR 5.67 95% CI 5.19\u20136.21) had a greater risk relative to the general population than younger women with cannabis use (aHR 3.22 95% CI 2.95\u20133.52).<\/p>\n<p><strong>Interpretation<\/strong> \u2014 ED visits for cannabis use were associated with an increased risk of having an incident healthcare visit for an anxiety disorder, particularly in young males. These findings have important clinical and policy implications given the increasing use of cannabis over time and trend towards legalization of cannabis.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background \u2014 There is ongoing uncertainty about whether cannabis use increases the risk of developing an anxiety disorder. In this study we estimated the risk of having an incident healthcare visit for an anxiety disorder following an emergency department (ED) visit for cannabis use and explored factors associated with increased risk. Methods \u2014 We used [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[24,16,34,56],"migration-helper-qa-sample-set":[],"class_list":["post-17354","journal_article","type-journal_article","status-publish","hentry","topic-acute-and-emergency-services","topic-children-and-young-people","topic-mental-health-and-addictions","topic-pharmacoepidemiology-and-drug-safety"],"acf":{"citation":"Myran DT, Harrison LD, Pugliese M, Tanuseputro P, Gaudreault A, Fiedorowicz JG, Solmi M. <em>EClinicalMedicine.<\/em> 2024; Feb 5 [Epub ahead of print].","source_url":"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102455","ices_scientist":[1107,17551],"site":[6734],"research_program":[6740],"news_release":[17355],"journal_article":"","atlas":"","research_report":"","infographic":[17356],"video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Development of an anxiety disorder following an emergency department visit due to cannabis use: a population-based cohort study<\/title>\n<meta name=\"description\" content=\"Background \u2014 There is ongoing uncertainty about whether cannabis use increases the risk of developing an anxiety disorder. 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