{"id":16488,"date":"2023-05-29T10:33:00","date_gmt":"2023-05-29T14:33:00","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&#038;p=16488"},"modified":"2023-07-28T10:39:48","modified_gmt":"2023-07-28T14:39:48","slug":"serum-urate-monitoring-among-older-adults-with-gout","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/serum-urate-monitoring-among-older-adults-with-gout\/","title":{"rendered":"Serum urate monitoring among older adults with gout: initiating urate-lowering therapy in Ontario, Canada"},"content":{"rendered":"<p><strong>Objective<\/strong> \u2014 To assess the proportion of, and factors associated with, older adults with gout receiving a serum urate (SUA) test after starting urate-lowering therapy (ULT).<\/p>\n<p><strong>Methods<\/strong> \u2014 We performed a population-based retrospective cohort study in Ontario, Canada in patients ages \u226566\u2009years with gout, newly dispensed ULT between 2010 and 2019. We characterized patients with SUA testing within 6 and 12 months after ULT dispensation. Multilevel logistic regression clustered by ULT prescriber evaluated the factors associated with SUA monitoring within 6 months.<\/p>\n<p><strong>Results<\/strong> \u2014 We included 44,438 patients with a mean \u00b1 SD age of 76.0 \u00b1\u20097.3\u2009years and 64.4% male. Family physicians prescribed 79.1% of all ULTs. SUA testing was lowest in 2010 (56.4% at 6 months) and rose over time to 71.3% in 2019 (P &lt;\u20090.0001). Compared with rheumatologists, family physicians (odds ratio [OR] 0.26 [95% confidence interval (95% CI) 0.23\u20130.29]), internists (OR 0.34 [95% CI 0.29\u20130.39]), nephrologists (OR 0.37 [95% CI 0.30\u20130.45]), and other specialties (OR 0.25 [95% CI 0.21\u20130.29]) were less likely to test SUA, as were male physicians (OR 0.87 [95% CI 0.83\u20130.91]). Patient factors associated with lower odds of SUA monitoring included rural residence (OR 0.81 [95% CI 0.77\u20130.86]), lower socioeconomic status (OR 0.91 [95% CI 0.85\u20130.97]), and patient comorbidities. Chronic kidney disease, hypertension, diabetes mellitus, and coprescription of colchicine\/oral corticosteroids (OR 1.31 [95% CI 1.23\u20131.40]) were correlated with increased SUA testing.<\/p>\n<p><strong>Conclusion<\/strong> \u2014 SUA testing is suboptimal among older adults with gout initiating ULT but is improving over time. ULT prescriber, patient, and prescription characteristics were correlated with SUA testing.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective \u2014 To assess the proportion of, and factors associated with, older adults with gout receiving a serum urate (SUA) test after starting urate-lowering therapy (ULT). Methods \u2014 We performed a population-based retrospective cohort study in Ontario, Canada in patients ages \u226566\u2009years with gout, newly dispensed ULT between 2010 and 2019. We characterized patients with [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[51,17],"migration-helper-qa-sample-set":[],"class_list":["post-16488","journal_article","type-journal_article","status-publish","hentry","topic-musculoskeletal-diseases-and-disorders","topic-older-people"],"acf":{"citation":"Kwok TSH, Kuriya B, Hawker G, Li P, Choy G, Widdifield J. <em>Arthritis Care Res (Hoboken)<\/em>. 2023; May 29 [Epub ahead of print].","source_url":"https:\/\/doi.org\/10.1002\/acr.25167","ices_scientist":[1267,1122],"site":[6733],"research_program":[6746],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | 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