{"id":16146,"date":"2023-06-20T11:06:50","date_gmt":"2023-06-20T15:06:50","guid":{"rendered":"https:\/\/www.ices.on.ca\/?post_type=journal_article&p=16146"},"modified":"2023-06-26T11:32:52","modified_gmt":"2023-06-26T15:32:52","slug":"comparison-of-medical-and-mental-health-sequelae-following-hospitalization-for-covid-19-influenza-and-sepsis","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/comparison-of-medical-and-mental-health-sequelae-following-hospitalization-for-covid-19-influenza-and-sepsis\/","title":{"rendered":"Comparison of medical and mental health sequelae following hospitalization for COVID-19, influenza, and sepsis"},"content":{"rendered":"

Importance<\/strong> – People who survive hospitalization for COVID-19 are at risk for developing new cardiovascular, neurological, mental health, and inflammatory autoimmune conditions. It is unclear how posthospitalization risks for COVID-19 compare with those for other serious infectious illnesses.<\/p>\n

Objective<\/strong> – To compare risks of incident cardiovascular, neurological, and mental health conditions and rheumatoid arthritis in 1 year following COVID-19 hospitalization against 3 comparator groups: prepandemic hospitalization for influenza and hospitalization for sepsis before and during the COVID-19 pandemic.<\/p>\n

Design, Setting, and Participants<\/strong> – This population-based cohort study included all adults hospitalized for COVID-19 between April 1, 2020, and October 31, 2021, historical comparator groups for people hospitalized for influenza or sepsis, and a contemporary comparator group of people hospitalized for sepsis in Ontario, Canada.<\/p>\n\n\n

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\n\t\t\tInfographic\t\t<\/h2>\n\t\t\n\t\t\t<\/div>\n\t
\n\t\t\t\t\t\t\n\t\t\tDownload infographic\t\t\t\n\n<\/svg>\n\t\t<\/a>\n\t\t\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\tClick here\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\n\t<\/div>\n\n\n

Exposure<\/strong> – Hospitalization for COVID-19, influenza, or sepsis.<\/p>\n

Results<\/strong> – Of 379 366 included adults (media [IQR] age, 75[63-85] years; 54% female), there were 26 499 people who survived hospitalization for COVID-19, 299 989 historical controls (17 516 for influenza and 282 473 for sepsis), and 52 878 contemporary controls hospitalized for sepsis. Hospitalization for COVID-19 was associated with an increased 1-year risk of venous thromboembolic disease compared with influenza (adjusted hazard ratio, 1.77; 95% CI, 1.36-2.31) but with no increased risks of developing selected ischemic and nonischemic cerebrovascular and cardiovascular disorders, neurological disorders, rheumatoid arthritis, or mental health conditions compared with influenza or sepsis cohorts.<\/p>\n

Conclusions and Relevance<\/strong> – In this cohort study, apart from an elevated risk of venous thromboembolism within 1 year, the burden of postacute medical and mental health conditions among those who survived hospitalization for COVID-19 was comparable with other acute infectious illnesses. This suggests that many of the postacute consequences of COVID-19 may be related to the severity of infectious illness necessitating hospitalization rather than being direct consequences of infection with SARS-CoV-2.<\/p>","protected":false},"excerpt":{"rendered":"

Importance – People who survive hospitalization for COVID-19 are at risk for developing new cardiovascular, neurological, mental health, and inflammatory autoimmune conditions. It is unclear how posthospitalization risks for COVID-19 compare with those for other serious infectious illnesses. Objective – To compare risks of incident cardiovascular, neurological, and mental health conditions and rheumatoid arthritis in […]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[42,62,39],"migration-helper-qa-sample-set":[],"class_list":["post-16146","journal_article","type-journal_article","status-publish","hentry","topic-chronic-diseases-and-multimorbidity","topic-health-services-research","topic-infectious-diseases"],"acf":{"citation":"Quinn KL, Stukel TA, Huang A, Abdel-Qadir H, Altaf A, Bell CM, Cheung AM, Detsky AS, Goulding S, Herridge M, Ivers N, Lapointe-Shaw L, Lapp J, McNaughton CD, Raissi A, Rosella LC, Warda N, Razak F, Verma AA. JAMA Intern Med<\/em>. 2023; e232228. Epub 2023 Jun 20.","source_url":"https:\/\/doi.org\/10.1001\/jamainternmed.2023.2228","ices_scientist":[1104,1372,1287,1273,1339,21862],"site":[6733],"research_program":[6747],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":[16147],"video":"","downloads":null,"links":null,"sitecore_item_id":"","sitecore_item_name":"","sitecore_field_values":"","previous_url":""},"yoast_head":"\nICES | Comparison of medical and mental health sequelae following hospitalization for COVID-19, influenza, and sepsis<\/title>\n<meta name=\"description\" content=\"Importance - People who survive hospitalization for COVID-19 are at risk for developing new cardiovascular, neurological, mental health, and inflammatory\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/comparison-of-medical-and-mental-health-sequelae-following-hospitalization-for-covid-19-influenza-and-sepsis\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | Comparison of medical and mental health sequelae following hospitalization for COVID-19, influenza, and sepsis\" \/>\n<meta property=\"og:description\" content=\"Importance - 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