{"id":15392,"date":"2023-05-26T00:00:00","date_gmt":"2023-05-26T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/publications\/journal-articles\/effect-of-free-medicine-distribution-on-health-care-costs-in-canada-over-3-years-a-secondary-analysis-of-the-clean-meds-randomized-clinical-trial\/"},"modified":"2023-07-24T15:37:11","modified_gmt":"2023-07-24T19:37:11","slug":"effect-of-free-medicine-distribution-on-health-care-costs-in-canada-over-3-years-a-secondary-analysis-of-the-clean-meds-randomized-clinical-trial","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/effect-of-free-medicine-distribution-on-health-care-costs-in-canada-over-3-years-a-secondary-analysis-of-the-clean-meds-randomized-clinical-trial\/","title":{"rendered":"Effect of free medicine distribution on healthcare costs in Canada over 3 years: a secondary analysis of the CLEAN Meds randomized clinical trial"},"content":{"rendered":"<p><strong>Importance<\/strong> \u2014 Few interventions are proven to reduce total healthcare costs, and addressing cost-related nonadherence has the potential to do so.<\/p>\n<p><strong>Objective<\/strong> \u2014 To determine the effect of eliminating out-of-pocket medication fees on total healthcare costs.<\/p>\n<p><strong>Design, Setting, and Participants<\/strong> \u2014 This secondary analysis of a multicenter randomized clinical trial using a prespecified outcome took place across 9 primary care sites in Ontario, Canada (6 in Toronto and 3 in rural areas), where healthcare services are generally publicly funded. Adult patients (\u226518 years old) reporting cost-related nonadherence to medicines in the past 12 months were recruited between June 1, 2016, and April 28, 2017, and followed up until April 28, 2020. Data analysis was completed in 2021.<\/p>\n<p><strong>Interventions<\/strong> \u2014 Access to a comprehensive list of 128 medicines commonly prescribed in ambulatory care with no out-of-pocket costs for 3 years vs usual medicine access.<\/p>\n<p><strong>Main Outcome and Measures<\/strong> \u2014 Total publicly funded healthcare costs over 3 years, including costs of hospitalizations. Healthcare costs were determined using administrative data from Ontario\u2019s single-payer healthcare system, and all costs are reported in Canadian dollars with adjustments for inflation.<\/p>\n<p><strong>Results<\/strong> \u2014 A total of 747 participants from 9 primary care sites were included in the analysis (mean [SD] age, 51 [14] years; 421 [56.4%] female). Free medicine distribution was associated with a lower median total healthcare spending over 3 years of $1641 (95% CI, $454-$2792; P = .006). Mean total spending was $4465 (95% CI, \u2212$944 to $9874) lower over the 3-year period.<\/p>\n<p><strong>Conclusions and Relevance<\/strong> \u2014 In this secondary analysis of a randomized clinical trial, eliminating out-of-pocket medication expenses for patients with cost-related nonadherence in primary care was associated with lower healthcare spending over 3 years. These findings suggest that eliminating out-of-pocket medication costs for patients could reduce overall costs of healthcare.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Importance \u2014 Few interventions are proven to reduce total healthcare costs, and addressing cost-related nonadherence has the potential to do so. Objective \u2014 To determine the effect of eliminating out-of-pocket medication fees on total healthcare costs. Design, Setting, and Participants \u2014 This secondary analysis of a multicenter randomized clinical trial using a prespecified outcome took [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[61,66],"migration-helper-qa-sample-set":[],"class_list":["post-15392","journal_article","type-journal_article","status-publish","hentry","topic-health-economics","topic-trials"],"acf":{"citation":"Persaud N, Bedard M, Boozary A, Glazier RH, Gomes T, Hwang SW, J\u00fcni P, Law MR, Mamdani M, Manns B, Martin D, Morgan SG, Oh P, Pinto AD, Shah BR, Sullivan F, Umali N, Thorpe KE, Tu K, Wu F, Laupacis A; CLEAN Meds study team. <em>JAMA Health Forum<\/em>. 2023; 4(5):e231127. Epub 2023 May 26.","source_url":"https:\/\/jamanetwork.com\/journals\/jama-health-forum\/fullarticle\/2805494","ices_scientist":[1250,1252,1271,1325,1361,1293],"site":[6733],"research_program":[6740],"news_release":"","journal_article":"","atlas":"","research_report":"","infographic":"","video":"","downloads":null,"links":null,"sitecore_item_id":"CA57F6A8-03A7-4F4F-BAC9-05FE890BF64C","sitecore_item_name":"Effect-of-free-medicine-distribution-on-health-care-costs-in-Canada-over-3-years","sitecore_field_values":"{\r\n  \"Title\": \"Effect of free medicine distribution on healthcare costs in Canada over 3 years: a secondary analysis of the CLEAN Meds randomized clinical trial\",\r\n  \"Short title\": \"Effect of free medicine distribution on\",\r\n  \"Summary\": \"The study aim was to determine the effect of eliminating out-of-pocket medication fees on total healthcare costs.\",\r\n  \"Citation\": \"<p>Persaud N, Bedard M, Boozary A, Glazier RH, Gomes T, Hwang SW, J&uuml;ni P, Law MR, Mamdani M, Manns B, Martin D, Morgan SG, Oh P, Pinto AD, Shah BR, Sullivan F, Umali N, Thorpe KE, Tu K, Wu F, Laupacis A; CLEAN Meds study team. <em>JAMA Health Forum<\/em>. 2023; 4(5):e231127. Epub 2023 May 26. DOI: <a href=\"https:\/\/doi.org\/10.1001\/jamahealthforum.2023.1127\" title=\"opens external link\">https:\/\/doi.org\/10.1001\/jamahealthforum.2023.1127<\/a><\/p>\",\r\n  \"Abstract\": \"<p><strong>Importance<\/strong> &mdash; Few interventions are proven to reduce total healthcare costs, and addressing cost-related nonadherence has the potential to do so.<\/p>n<p><strong>Objective<\/strong> &mdash; To determine the effect of eliminating out-of-pocket medication fees on total healthcare costs.<\/p>n<p><span class=\"bold\">Design, Setting, and Participants<\/span> &mdash; This secondary analysis of a multicenter randomized clinical trial using a prespecified outcome took place across 9 primary care sites in Ontario, Canada (6 in Toronto and 3 in rural areas), where healthcare services are generally publicly funded. Adult patients (&ge;18 years old) reporting cost-related nonadherence to medicines in the past 12 months were recruited between June 1, 2016, and April 28, 2017, and followed up until April 28, 2020. Data analysis was completed in 2021.<\/p>n<p><strong>Interventions<\/strong> &mdash; Access to a comprehensive list of 128 medicines commonly prescribed in ambulatory care with no out-of-pocket costs for 3 years vs usual medicine access.<\/p>n<p><span class=\"bold\">Main Outcome and Measures<\/span> &mdash; Total publicly funded healthcare costs over 3 years, including costs of hospitalizations. Healthcare costs were determined using administrative data from Ontario&rsquo;s single-payer healthcare system, and all costs are reported in Canadian dollars with adjustments for inflation.<\/p>n<p><strong>Results<\/strong> &mdash; A total of 747 participants from 9 primary care sites were included in the analysis (mean [SD] age, 51 [14] years; 421 [56.4%] female). Free medicine distribution was associated with a lower median total healthcare spending over 3 years of $1641 (95% CI, $454-$2792; P = .006). Mean total spending was $4465 (95% CI, &minus;$944 to $9874) lower over the 3-year period.<\/p>n<p><span class=\"bold\">Conclusions and Relevance<\/span> &mdash; In this secondary analysis of a randomized clinical trial, eliminating out-of-pocket medication expenses for patients with cost-related nonadherence in primary care was associated with lower healthcare spending over 3 years. These findings suggest that eliminating out-of-pocket medication costs for patients could reduce overall costs of healthcare.<\/p>n<p><a href=\"https:\/\/jamanetwork.com\/journals\/jama-health-forum\/fullarticle\/2805494\" title=\"opens external link\">View full text<\/a><\/p>\",\r\n  \"ICES Scientists\": \"{2C81C93C-B401-432B-8741-83841744D4CA}|{1FA4634A-81DF-4A25-8739-98ABF3872B45}|{0C9AB207-93FF-44DC-91F0-579DF3D39255}|{F2F916BC-2EE9-4C65-BCAB-086ED6BB971A}|{4CA3655C-D15C-43EC-8F5D-9FE401C24F27}|{317B49F2-8847-47FC-870B-744C1E01E26F}|{83920C20-06BE-4C6B-9FA7-06B69A509A24}\",\r\n  \"Posted Date\": \"20230526T000000\",\r\n  \"Show on Publications Landing Page\": \"1\"\r\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2023\/May\/Effect-of-free-medicine-distribution-on-health-care-costs-in-Canada-over-3-years"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Effect of free medicine distribution on healthcare costs in Canada over 3 years: a secondary analysis of the CLEAN Meds randomized clinical trial<\/title>\n<meta name=\"description\" content=\"Importance \u2014 Few interventions are proven to reduce total healthcare costs, and addressing cost-related nonadherence has the potential to do so. 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