{"id":1531,"date":"2014-05-29T00:00:00","date_gmt":"2014-05-29T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/greater-mortality-risk-among-patients-with-delayed-follow-up-after-implantable-cardioverter-defibrillator-procedures\/"},"modified":"2023-06-14T19:39:14","modified_gmt":"2023-06-14T23:39:14","slug":"greater-mortality-risk-among-patients-with-delayed-follow-up-after-implantable-cardioverter-defibrillator-procedures","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/greater-mortality-risk-among-patients-with-delayed-follow-up-after-implantable-cardioverter-defibrillator-procedures\/","title":{"rendered":"Greater mortality risk among patients with delayed follow-up after implantable cardioverter defibrillator procedures"},"content":{"rendered":"<p><strong>Background<\/strong> &#x2014; Substantial numbers of deaths occur among implantable cardioverter defibrillator (ICD) recipients. Timely follow-up after ICD implantation may improve patient outcomes. The researchers&apos; objective was to examine follow-up care and outcomes among patients undergoing ICD implantation. <\/p>\n<p><strong>Methods<\/strong> &#x2014;&#xa0;The researchers&#xa0;compared patient characteristics and outcomes of those with late (&gt;12 weeks) vs. early defibrillator clinic follow-up after ICD implantation in the Ontario ICD Database from 2007-2011. The researchers examined the impact of post-implant ICD clinic follow-up visits compared with primary care physician tracer on mortality outcomes using time-varying covariate analysis. <\/p>\n<p><strong>Results <\/strong>&#x2014; Among 8096 ICD recipients (age 64.6 &#xb1; 12.6 years), 1145 (14%) received delayed follow-up. Patients with early ICD clinic follow-up experienced reduced risk of all-cause mortality, with hazards ratio [HR] 0.69 (95%CI; 0.50&#x2013;0.95, p=0.023) adjusted for clinical factors, post-discharge primary care visits, and distance to follow-up center. Early ICD clinic follow-up was associated with a reduction in out-of-hospital death with adjusted HR 0.52 (95%CI; 0.36&#x2013;0.76, p=0.001) but not with a significant change in cardiovascular hospitalizations. In a tracer analysis, early primary care physician follow-up was associated with a nonsignificant trend towards increased mortality with adjusted HR 1.48 (95%CI; 0.97&#x2013;2.25, p=0.072). Reduced eGFR, secondary prevention or replacement devices, myocardial ischemia, smoking, and greater geographic distance to the implanting center increased the odds of delayed follow-up.<\/p>\n<p><strong>Conclusions<\/strong> &#x2014; After device implantation, early defibrillator clinic follow-up was associated with reduced risk of all-cause and out-of-hospital death compared to those experiencing delayed follow-up. This study examines the relationship between delayed follow-up (&gt;12 weeks) at a specialized implantable cardioverter defibrillator (ICD) clinic and outcomes in patients receiving ICDs. Among 8096 ICD recipients, 1145 patients (14%) received delayed follow-up. Patients experiencing early follow-up after ICD implantation exhibited reduced risk of all cause mortality, and reduced out-of-hospital death without a significant change in cardiovascular hospitalizations.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background &#x2014; Substantial numbers of deaths occur among implantable cardioverter defibrillator (ICD) recipients. Timely follow-up after ICD implantation may improve patient outcomes. The researchers&apos; objective was to examine follow-up care and outcomes among patients undergoing ICD implantation. Methods &#x2014;&#xa0;The researchers&#xa0;compared patient characteristics and outcomes of those with late (&gt;12 weeks) vs. early defibrillator clinic follow-up [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[24,40],"migration-helper-qa-sample-set":[],"class_list":["post-1531","journal_article","type-journal_article","status-publish","hentry","topic-acute-and-emergency-services","topic-cardiovascular-disease"],"acf":{"citation":"Laksman ZW, Krahn AD, Dorian P, Simpson CS, Crystal E,&#xa0;Healey JS, Khaykin Y, Wang X, Lee DS. <em>Can J Cardiol.<\/em> 2014; 30(6):598&#x2013;605.","source_url":"","ices_scientist":[1290,1363],"site":[6733],"research_program":[6742],"news_release":[7332],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"7FE0FE7D-6EF2-43D6-9E11-610075BE5197","sitecore_item_name":"Greater-mortality-risk-among-patients-with-delayed-follow-up-after-ICD","sitecore_field_values":"{\n  \"Title\": \"Greater mortality risk among patients with delayed follow-up after implantable cardioverter defibrillator procedures\",\n  \"Short title\": \"Greater mortality risk among patients\",\n  \"Summary\": \"Substantial numbers of deaths occur among implantable cardioverter defibrillator (ICD) recipients. Timely follow-up after ICD implantation may improve patient outcomes.\",\n  \"Citation\": \"<p>Laksman ZW, Krahn AD, Dorian P, Simpson CS, Crystal E,&nbsp;Healey JS, Khaykin Y, Wang X, Lee DS. <em>Can J Cardiol.<\/em> 2014; 30(6):598&ndash;605.<\/p>\",\n  \"Abstract\": \"<p><strong>Background<\/strong> &mdash; Substantial numbers of deaths occur among implantable cardioverter defibrillator (ICD) recipients. Timely follow-up after ICD implantation may improve patient outcomes. The researchers' objective was to examine follow-up care and outcomes among patients undergoing ICD implantation. <\/p>n<p><strong>Methods<\/strong> &mdash;&nbsp;The researchers&nbsp;compared patient characteristics and outcomes of those with late (&gt;12 weeks) vs. early defibrillator clinic follow-up after ICD implantation in the Ontario ICD Database from 2007-2011. The researchers examined the impact of post-implant ICD clinic follow-up visits compared with primary care physician tracer on mortality outcomes using time-varying covariate analysis. <\/p>n<p><strong>Results <\/strong>&mdash; Among 8096 ICD recipients (age 64.6 &plusmn; 12.6 years), 1145 (14%) received delayed follow-up. Patients with early ICD clinic follow-up experienced reduced risk of all-cause mortality, with hazards ratio [HR] 0.69 (95%CI; 0.50&ndash;0.95, p=0.023) adjusted for clinical factors, post-discharge primary care visits, and distance to follow-up center. Early ICD clinic follow-up was associated with a reduction in out-of-hospital death with adjusted HR 0.52 (95%CI; 0.36&ndash;0.76, p=0.001) but not with a significant change in cardiovascular hospitalizations. In a tracer analysis, early primary care physician follow-up was associated with a nonsignificant trend towards increased mortality with adjusted HR 1.48 (95%CI; 0.97&ndash;2.25, p=0.072). Reduced eGFR, secondary prevention or replacement devices, myocardial ischemia, smoking, and greater geographic distance to the implanting center increased the odds of delayed follow-up.<\/p>n<p><strong>Conclusions<\/strong> &mdash; After device implantation, early defibrillator clinic follow-up was associated with reduced risk of all-cause and out-of-hospital death compared to those experiencing delayed follow-up. This study examines the relationship between delayed follow-up (&gt;12 weeks) at a specialized implantable cardioverter defibrillator (ICD) clinic and outcomes in patients receiving ICDs. Among 8096 ICD recipients, 1145 patients (14%) received delayed follow-up. Patients experiencing early follow-up after ICD implantation exhibited reduced risk of all cause mortality, and reduced out-of-hospital death without a significant change in cardiovascular hospitalizations.<\/p>\",\n  \"Keywords\": \"{92E2791D-5DAB-4244-8A85-434D524D9A12}|{8DA96C16-E06B-4D90-802D-73D8A7C9612E}|{E93E0287-ACCB-4952-BB98-00EF52815525}\",\n  \"Related Products\": \"<h2>News Release<\/h2>rn<h3><a href=\"~\/link.aspx?_id=CEEB40045AB44D5685976889200CD561&amp;_z=z\">Early followup care after ICD procedure associated with 31 per cent reduction in death: ICES study<\/a><\/h3>rn<h2><a href=\"~\/link.aspx?_id=2F3FF37C088747AA987C04BA1C142AE9&amp;_z=z\">IN THE NEWS<\/a><\/h2>rn<h3><a href=\"http:\/\/www.medscape.com\/viewarticle\/825879\" title=\"TheHeart.org\" target=\"_blank\">Delaying Follow-up With ICD Patients Is Associated With Increased Mortality Risks <\/a><\/h3>\",\n  \"Research Programs\": \"{BEC72DE0-BA8C-42B8-ACE5-EE29FFB2CB3B}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}\",\n  \"ICES Scientists\": \"{CEEE13AD-C7DE-455F-ACF8-AAD7D27BB178}|{3837E208-A045-4A55-9113-CA067609FCF2}\",\n  \"Posted Date\": \"20140529T000000\",\n  \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/Publications\/Journal-Articles\/2014\/January\/Greater-mortality-risk-among-patients-with-delayed-follow-up-after-ICD"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | Greater mortality risk among patients with delayed follow-up after implantable cardioverter defibrillator procedures<\/title>\n<meta name=\"description\" content=\"Background &#x2014; Substantial numbers of deaths occur among implantable cardioverter defibrillator (ICD) recipients. 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