{"id":1401,"date":"2014-08-22T00:00:00","date_gmt":"2014-08-22T04:00:00","guid":{"rendered":"https:\/\/icesontario.wpengine.com\/journal-articles\/a-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention\/"},"modified":"2023-06-14T19:22:54","modified_gmt":"2023-06-14T23:22:54","slug":"a-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention","status":"publish","type":"journal_article","link":"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/a-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention\/","title":{"rendered":"A prescription at discharge improves long-term adherence for secondary stroke prevention"},"content":{"rendered":"<p><strong>Background<\/strong> &#x2014; Medication adherence is important for optimal secondary stroke prevention. We evaluated short-term adherence to antihypertensive and lipid-lowering agents after a new ischemic stroke, as predictor of adherence at 1 and 2 years. <\/p>\n<p><strong>Methods<\/strong> &#x2014; A 5-year cohort of patients from 11 institutions in the Registry of the Canadian Stroke Network was linked to population-based administrative health records. Patients diagnosed with acute ischemic stroke and discharged home were included. Medication adherence was assessed through documented prescription filling at 7 days, 1 year, and 2 years.<\/p>\n<p><strong>Results<\/strong> &#x2014; From 2003 to 2008, 6437 ischemic stroke patients were discharged home from hospital, and 1126 patients filled a prescription for antihypertensive and lipid-lowering agents within 7 days of discharge. Patients provided with a prescription at discharge were more likely to show adherence at 7 days. Adherence at 1 year remains higher in these patients for antihypertensive (93.8% vs. 87.7%; odds ratio [OR], 2.31; 95% confidence interval [CI], 1.69-3.16), lipid-lowering agents (88% vs. 81.6%; OR, 1.77; 95% CI, 1.36-2.32), or both (85.8% vs. 79.9%; OR, 1.72; 95% CI, 1.32-2.25). Findings are similar at 2 years for antihypertensive (92.2% vs. 87.7%; OR, 1.78; 95% CI, 1.3-2.43), lipid-lowering agents (82.6% vs. 79.0%; OR, 1.31; 95% CI, 1.01-1.69), or both (81.1% vs. 77.0%; OR, 1.4; 95% CI, 1.09-1.82).<\/p>\n<p><strong>Conclusions<\/strong> &#x2014; Provision of a prescription strengthens adherence at 1 week from discharge for both prior and new users of antihypertensive and lipid-lowering drugs. Medication adherence at 1 week after discharge for acute ischemic stroke predicts adherence for secondary preventive therapies at 1 and 2 years.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background &#x2014; Medication adherence is important for optimal secondary stroke prevention. We evaluated short-term adherence to antihypertensive and lipid-lowering agents after a new ischemic stroke, as predictor of adherence at 1 and 2 years. Methods &#x2014; A 5-year cohort of patients from 11 institutions in the Registry of the Canadian Stroke Network was linked to [&hellip;]<\/p>\n","protected":false},"template":"","migration-helper-automated":[],"migration-manual":[],"topic":[40,56,35],"migration-helper-qa-sample-set":[87],"class_list":["post-1401","journal_article","type-journal_article","status-publish","hentry","topic-cardiovascular-disease","topic-pharmacoepidemiology-and-drug-safety","topic-public-health","migration-helper-qa-sample-set-journal-articles-set-a"],"acf":{"citation":"Tsai JP, Rochon PA, Raptis S, Bronskill SE, Bell CM, Saposnik G. <em>J Stroke Cerebrovasc Dis<\/em>. 2014; 23(9):2308-15. Epub 2014 Aug 22.","source_url":"","ices_scientist":[1340,1159,1172,1365,17132],"site":[6733,6735],"research_program":[6746,6742,6740],"news_release":[7318],"journal_article":[],"atlas":[],"research_report":[],"infographic":[],"video":[],"downloads":null,"links":null,"sitecore_item_id":"2B7A16C8-BC25-4042-8172-150D3B657739","sitecore_item_name":"A-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention","sitecore_field_values":"{\n  \"Title\": \"A prescription at discharge improves long-term adherence for secondary stroke prevention\",\n  \"Short title\": \"A prescription at discharge improves\",\n  \"Summary\": \"The researchers evaluated short-term adherence to antihypertensive and lipid-lowering agents after a new ischemic stroke, as predictor of adherence at 1 and 2 years. rn\",\n  \"Citation\": \"<p>Tsai JP, Rochon PA, Raptis S, Bronskill SE, Bell CM, Saposnik G. <em>J Stroke Cerebrovasc Dis<\/em>. 2014; 23(9):2308-15. Epub 2014 Aug 22.<\/p>\",\n  \"Abstract\": \"<p><strong>Background<\/strong> &mdash; Medication adherence is important for optimal secondary stroke prevention. We evaluated short-term adherence to antihypertensive and lipid-lowering agents after a new ischemic stroke, as predictor of adherence at 1 and 2 years. <\/p>rn<p><strong>Methods<\/strong> &mdash; A 5-year cohort of patients from 11 institutions in the Registry of the Canadian Stroke Network was linked to population-based administrative health records. Patients diagnosed with acute ischemic stroke and discharged home were included. Medication adherence was assessed through documented prescription filling at 7 days, 1 year, and 2 years.<\/p>rn<p><strong>Results<\/strong> &mdash; From 2003 to 2008, 6437 ischemic stroke patients were discharged home from hospital, and 1126 patients filled a prescription for antihypertensive and lipid-lowering agents within 7 days of discharge. Patients provided with a prescription at discharge were more likely to show adherence at 7 days. Adherence at 1 year remains higher in these patients for antihypertensive (93.8% vs. 87.7%; odds ratio [OR], 2.31; 95% confidence interval [CI], 1.69-3.16), lipid-lowering agents (88% vs. 81.6%; OR, 1.77; 95% CI, 1.36-2.32), or both (85.8% vs. 79.9%; OR, 1.72; 95% CI, 1.32-2.25). Findings are similar at 2 years for antihypertensive (92.2% vs. 87.7%; OR, 1.78; 95% CI, 1.3-2.43), lipid-lowering agents (82.6% vs. 79.0%; OR, 1.31; 95% CI, 1.01-1.69), or both (81.1% vs. 77.0%; OR, 1.4; 95% CI, 1.09-1.82).<\/p>rn<p><strong>Conclusions<\/strong> &mdash; Provision of a prescription strengthens adherence at 1 week from discharge for both prior and new users of antihypertensive and lipid-lowering drugs. Medication adherence at 1 week after discharge for acute ischemic stroke predicts adherence for secondary preventive therapies at 1 and 2 years.<\/p>\",\n  \"Keywords\": \"{F98C94A2-8572-460A-BAB2-70B54560A83C}|{E35EA75E-2C35-42CC-90D1-00302436CB1C}|{D130ADD9-0370-4BF6-9BBB-7379AF0263F0}\",\n  \"Related Products\": \"<h2>News release<\/h2>rn<h3><a href=\"~\/link.aspx?_id=0831536EEE204811999037B39373711F&amp;_z=z\">A prescription for better stroke care<\/a><\/h3>\",\n  \"Research Programs\": \"{CFE36C89-C969-4C23-B5E4-1BA9E5BDC273}|{BEC72DE0-BA8C-42B8-ACE5-EE29FFB2CB3B}|{46DF28D2-EDE8-4DF2-8CC0-87CEF464E435}\",\n  \"ICES Locations\": \"{4FCAABBA-14A5-42E6-8F33-BC6C2F1D9908}|{FBE2D1B1-C0BA-423F-8D16-39466B6C1424}\",\n  \"ICES Scientists\": \"{14B76C34-3A35-4785-86C4-9B1633E28765}|{68FD9EE5-974B-4CED-A597-82186232FF1D}|{9F60496B-63FD-4BE5-A7EF-C4969D7AACB3}|{9F556094-95ED-4001-9E45-0094CCC54588}\",\n  \"Posted Date\": \"20140822T000000\",\n  \"Show on Publications Landing Page\": \"1\"\n}","previous_url":"https:\/\/www.ices.on.ca\/publications\/journal-articles\/a-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention\/"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ICES | A prescription at discharge improves long-term adherence for secondary stroke prevention<\/title>\n<meta name=\"description\" content=\"Background &#x2014; Medication adherence is important for optimal secondary stroke prevention. We evaluated short-term adherence to antihypertensive and\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ices.on.ca\/fr\/publications\/journal-articles\/a-prescription-at-discharge-improves-long-term-adherence-for-secondary-stroke-prevention\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ICES | A prescription at discharge improves long-term adherence for secondary stroke prevention\" \/>\n<meta property=\"og:description\" content=\"Background &#x2014; Medication adherence is important for optimal secondary stroke prevention. 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